A5064899978- Gut microbiota and health
- Animal Nutrition and Physiology
- Wound Healing and Treatments
- Clostridium difficile and Clostridium perfringens research
- Probiotics and Fermented Foods
- Hippo pathway signaling and YAP/TAZ
- Diabetic Foot Ulcer Assessment and Management
- Hydrogen's biological and therapeutic effects
- Analytical chemistry methods development
- Hedgehog Signaling Pathway Studies
- Mesenchymal stem cell research
- Medical Research and Treatments
- Analytical Chemistry and Chromatography
- Effects and risks of endocrine disrupting chemicals
- Viral gastroenteritis research and epidemiology
- Cancer-related molecular mechanisms research
- Heavy Metal Exposure and Toxicity
- Digestive system and related health
- Diet and metabolism studies
- Cancer Research and Treatments
- Epigenetics and DNA Methylation
- Gastrointestinal motility and disorders
- Cancer-related Molecular Pathways
- Thallium and Germanium Studies
- Mitochondrial Function and Pathology
First Affiliated Hospital of Zhengzhou University
2025
Hunan First Normal University
2017-2025
Institute of Subtropical Agriculture
2017-2024
Chinese Academy of Sciences
2017-2024
Beijing Institute of Optoelectronic Technology
2023
Beijing Institute of Technology
2010-2023
Huazhong University of Science and Technology
2004-2023
Gannan Medical University
2018-2022
Zhejiang Chinese Medical University
2022
Hunan Normal University
2009-2019
Essential oils (EO) are promising feed additives for their antibacterial, antioxidant, and immune-enhancing abilities with low toxicity. Carvacrol, thymol, cinnamaldehyde commonly used to synthesize EO. However, few studies focus on combining these three EO in early-weaned piglets. In the present study, 24 piglets weaned at 21 d of age were randomly divided into 2 groups (6 replicate pens per group, pen). The fed a basal diet (the control group) supplemented 400 mg/kg (a blend consisting...
Coronary Artery Calcification (CAC) is a major risk factor for various cardiovascular diseases. Low-Density Lipoprotein Cholesterol (LDL-C) significant in atherosclerotic diseases and usually elevated patients with Type 2 Diabetes Mellitus (T2DM). However, the association between LDL-C levels incident CAC asymptomatic T2DM remains unclear. This study single-center retrospective cohort conducted from January 2018 to December 2023, including 2,631 who underwent regular health screenings. All...
Maternal gut microflora changes dramatically during perinatal period and plays a vital role in animal health reproductive performance. However, little is known about the microbial differences between sows with different productive capacities period. Hence, this study explored fecal diversity, composition, metabolic functions, phenotypes high capacity (HPC, litter size ≥ 15) low (LPC, ≤ 7) late pregnancy (LP, third day before due date) early stage after parturition (EAP, parturition) as well...
Lysozyme has been studied as a potential alternative to antibiotics for animals in recent years. The aim of this study was evaluate the effect dietary lysozyme on growth performance, serum biochemical parameters, immune response and gut health growing pigs.A total 216 pigs (19.81 ± 0.47 kg) were fed diets supplemented with colistin sulfate at 20 mg kg-1 (control), or 50 (L50) 100 (L100) diet 30 days. results showed that L100 control had greater average daily gain gain-to-feed ratio than L50...
Ethanolamine (Etn) contained in milk is the base constituent of phosphatidylethanolamine and required for proliferation intestinal epithelial cells bacteria, which important maintenance gut microbiome development. The present study investigated effect Etn on function using 21-d-old Sprague-Dawley rats treated with 0, 250, 500 1000 μm drinking water 2 weeks immediately after weaning. Growth performance, morphology, antioxidant capacity mucosal immunity, as well microbiota community...
Abstract Folate is increasingly thought to promote gastrointestinal health and regulate the diversity of gut microbiota alleviate weaning stress in piglets. The present study was conducted investigate effects folate on organ weight, digesta pH, short-chain fatty acids (SCFAs) concentration, intestinal weaned A total 28 piglets (6.73 ± 0.62 kg) were allocated four dietary treatments consisting a control group, 3, 9, 18 mg/kg supplementation 14-d feeding trial. results showed that fed with 9...
The aim of current study was to determine variations in sow's gut microbiota, serum immunity, and milk metabolite profile mediated by lysozyme supplementation. Twenty-four pregnant sows were assigned a control group without supplementation two treatments with 0.5 kg/t 1.0 provided formula feed for 21 days (n = 8 per treatment). Microbiota analysis metagenomic predictions based on 16s RNA high-throughput sequencing. Milk metabolome assessed untargeted liquid chromatography tandem mass...
Zearalenone (ZEN), a non-steroidal estrogenic mycotoxin produced by Fusarium graminearum species, poses significant threat to both human food safety and animal feed quality. In this study, we isolated strain, designated as Bacillus licheniformis YJ25, from contaminated moldy corn sample, demonstrating substantial effectiveness in removing ZEN. Our findings revealed that YJ25’s ZEN removal occurs primarily through cell wall adsorption, with enzymatic degradation representing potential...
Abstract Magnetic resonance arthrography, a procedure where contrast agents containing gadolinium are administered intra‐articularly, has become useful tool in musculoskeletal diagnosis. Although considered safe for systemic use, toxicities some tissues have been identified both free ion and the chelates used as contrast. In this study, effects of short‐term exposure articular chondrocytes to were examined by assaying proteoglycan synthesis, cell proliferation, apoptosis. Bovine grown...
Beta-glucan has been shown to have a beneficial effect on gastrointestinal health. This experiment was conducted investigate the effects of β-glucan isolated from Agrobacterium sp. ZX09 growth performance and intestinal health weaning pigs. A total 108 weaned pigs (21 d age; 6.05 ± 0.36 kg) were randomly divided into 3 groups (6 pens/group; 6 pigs/pen), each treated with following diets: 1) basal diet, 2) diet supplemented 20 mg/kg olaquindox, 3) 200 β-glucan, for 21 d. Compared control...
1 alpha, 25-Dihydroxyvitamin D3 [1 25-(OH)2D3], the hormonal form of vitamin D3, is further metabolized in kidney and intestine through carbon 24 (C-24) oxidation pathway initiated by C-24 hydroxylation, 23 (C-23) C-23 hydroxylation. The leading to formation calcitroic acid has been previously reported be present bone cells, but 25-(OH)2D3-26,23-lactone not described even though noted have a significant effect on formation. Therefore, study, we investigated production normal human...
Hydroquinone (HQ) is widely used in food stuffs and an occupational environmental pollutant. Although the hepatotoxicity of HQ has been demonstrated both vitro vivo, prevention HQ‐induced yet to be elucidated. In this study, we focused on intervention effect aqueous extracts Flos lonicerae Japonicae (FLJ) cytotoxicity. We that reduced cell viability a concentration‐dependent manner by administering 160 μ mol/L for 12 h as positive control The FLJ significantly increased decreased LDH...
The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein kinase family. Their functions in regulating animal development have been well studied both invertebrates and vertebrates. However, it remains to be determined whether they play a role sex determination. Here we present first evidence show that expression JNK1 displays distinct patterns during reversal rice-field eel. Molecular cloning reveals is conserved among eel other Both quantitative real-time polymerase...
Diabetic foot ulcers (DFUs) represent a severe complication of diabetes associated with reduced quality life, lower limb amputations, hospitalizations, increased incidence, and mortality. Importantly, significant number pathogenic genes remain unexplored in DFUs.A series bioinformatics analyses were performed on publicly available bulk transcriptome sequencing datasets GSE134431 GSE80178 to explore the transcriptomic changes DFUs select core for vitro functional validation. In focused...