A5004951824- Lysosomal Storage Disorders Research
- Cerebrovascular and genetic disorders
- Advanced Radiotherapy Techniques
- Antibiotic Resistance in Bacteria
- Acupuncture Treatment Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Cancer Studies
- Moyamoya disease diagnosis and treatment
- Traditional Chinese Medicine Studies
- Healthcare and Venom Research
- Pharmaceutical and Antibiotic Environmental Impacts
- AI in cancer detection
- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Hearing Loss and Rehabilitation
- Neurological Disease Mechanisms and Treatments
- Nanoplatforms for cancer theranostics
- Radiation Therapy and Dosimetry
- Speech and Audio Processing
- Medical Research and Treatments
- Oral health in cancer treatment
- Postharvest Quality and Shelf Life Management
- Nanocomposite Films for Food Packaging
- Botulinum Toxin and Related Neurological Disorders
- Mycobacterium research and diagnosis
Hebei University of Science and Technology
2023-2025
Linyi University
2024-2025
Guangzhou Medical University
2015-2025
Guangzhou Medical University Cancer Hospital
2015-2025
State Forestry and Grassland Administration
2025
Shandong Agricultural University
2025
Shanxi Normal University
2024
Affiliated Hospital of North Sichuan Medical College
2024
Zhujiang Hospital
2021-2023
Heilongjiang University of Chinese Medicine
2017-2023
The utilization of functional cling films presents a promising approach to alleviate post-harvest spoilage caused by microbial activity, oxidative metabolism, and moisture loss in agricultural products. To overcome the environmental problems conventional packaging materials, this study, we developed fruit vegetable based on glycidyltrimethylammonium chloride rosemarinic acid cross-linked gelatin (RQ-GEL). results indicate that prepared RQ-GEL film possesses excellent UV light barrier...
Traditional petroleum-based food-packaging materials have poor permeability, limited active packaging properties, and difficulty in biodegradation, limiting their application. We developed a carboxymethylated tamarind seed polysaccharide composite film incorporated with ε-polylysine (CTPε) for better application fresh-cut agricultural products. The CTPε films exhibit excellent water vapor barrier but the mechanical properties are slightly reduced. Fourier transform infrared spectroscopy...
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Radio- and chemo-resistance represent major obstacles in the therapy of non-small-cell lung cancer (NSCLC) underlying molecular mechanisms are not known. In present study, during induction radio- or NSCLC cells, dynamic analyses revealed that decreased expression let-7 induced by irradiation cisplatin resulted increased its target gene LIN28, LIN28 then contributed to further inhibiting maturation biogenesis. Moreover, we showed down-regulation up-regulation promoted resistance regulating...
In this study, a sensitive diagnosis and spontaneously photocatalytic therapy of cancer based on chemiluminescence (CL) nanozyme was studied. Briefly, carbon nitride-supported copper nanoparticles (CuCNs) loaded with luminol (CuCN-L) were utilized to develop microneedle patch (CuCN-L/MN). The CuCN-L probe could target overexpressed H2O2 in the TME actively emit CL achieve cell imaging for diagnosis. addition, 425 nm blue-violet photocatalyze CuCN reduce dioxide (CO2) monoxide (CO) gas (GT)....
ABSTRACT Salt stress is a major abiotic restrict plant growth and distribution. In our previous study, we found the ABI5‐BINDING PROTEIN 2a ( PagAFP2a ) gene was rapidly significantly induced by salt in hybrid poplar Populus alba × glandulosa ), however, its function responses unclear. this further demonstrated that expression ABA treatments. Additionally, ABA‐responsive element (ABRE) binding proteins (PagAREB1s) directly bind to promoter activate expression. Physiological analysis showed...
A novel localized surface plasmon resonance (LSPR) light-scattering sensor for Ag+ was developed with unmodified gold nanoparticles (AuNPs), based upon the specific recognition property of a cytosine–cytosine mismatched base pair. The addition induced oligonucleotide 5′-TAC ATA CAT ACT ATC TAT CTA-3′ to be desorbed from AuNPs, resulting in aggregation accompanied by dramatic enhancement LSPR intensity. intensity proportional concentration range 0.13–1.12 μM, limit detection 62.0 nM. results...
With the widespread use of antibiotics in medicine and agriculture, spread antibiotic resistance genes （ARGs） environment has become a serious threat to ecological balance human health, particularly for its role facilitating emergence multidrug-resistant pathogens. The study riverine environments as major transmission route ARGs closely related mobile genetic elements （MGEs） is great importance. MGEs exacerbate by horizontal transfer bacterial populations. Although studies have been...
Purpose: Acute ischemic stroke (AIS) is a leading health problem caused by cerebral ischemia/reperfusion (CI/R). This study aimed to unveil the potential clinical value and mechanism of lncRNA CASC15. Patients Methods: The expression CASC15, miR-338-3p was detected quantitative real-time PCR (qRT-PCR). correlations between CASC15 national institutes scale (NIHSS) scores or were evaluated Pearson correlation. A receiver operating characteristic (ROC) curve performed provide diagnostic Cell...
This study was to explore the most appropriate radiomics modeling method predict progression-free survival of EGFR-TKI treatment in advanced non-small cell lung cancer with EGFR mutations. Different machine learning methods may vary considerably and selection a proper model is essential for accurate outcome prediction. Our were established 176 discrimination models constructed 22 feature 8 classifiers. The predictive performance each evaluated using AUC, ACC, sensitivity specificity, where...
As a potential "Superbug," Pseudomonas aeruginosa remains the leading concern in antimicrobial resistance. In this study, emergence of clinical P. isolate was found to carry crpP and blaGES-5 on chromosome blaKPC-2 plasmid. A strain Guangzhou-PaeC79 with an extensively drug-resistant phenotype isolated, which resistant all classes commonly used antibiotics. It contains one chromosomal DNA plasmid, seven acquired resistance genes identified chromosome, including carbapenem gene...
Rats were divided into six groups: sham/control, Dl-3-n-butylphthalide, P1 (low phenytoin, 100 mg/kg), P2 (high 200 NP1 (Dl-3-n-butylphthalide 80 mg/kg, phenytoin NP2 mg/kg). Hematoxylin/eosin and Nissl staining showed that, compared to the sham/control group, Dl-3-n-butylphthalide group had no obvious hippocampal cerebellar neuron loss, but there was a significant loss in groups (P < 0.05), which more 0.05). The positive expression of Bax Bcl-2 proteins neurons not significantly...
Pyruvate kinase I (PykF) is one of the key enzymes glycolysis and plays a crucial role in bacterial metabolism. Several acetylation sites Vibrio alginolyticus PykF were reported previous studies then 11 first verified this study, however, specific roles remains unclear. Overlap-PCR homologous recombination implied to delete V. pykF gene constructed complementary strains site-directed mutagenesis for further research focus on deacetylation regulation PykF. The results showed that pyruvate...
Microbial communities play an important role in water quality regulation and biogeochemical cycles lakes, their community structure function are affected by environmental factors. Therein, antibiotics affect the abundance, diversity, composition, of microbial communities. In this study, Baiyangdian Lake was selected as study area. Sediment samples 16 sites were collected August 2018 April 2019, respectively. Ultra-high performance liquid chromatography-mass spectrometry （HPLC-MS/MS） used to...
Increasing attention has been paid to the heavy metal pollution in groundwater. The source analysis and risk assessment of metals will provide data method support for targeted control In this study, 20 sampling sites were selected Shijiazhuang City. APCS-MLR model health applied analyze evaluate sources risks 10 types groundwater Shijiazhuang. results showed that ① mean concentration followed order Fe>Zn>Mn>Cu>Al>Pb>Cr>As>Cd>Hg, ρ(Fe) ρ(Pb) 260.3 μg·L-1 10.01 μg·L-1, respectively. According...
Abstract Objective. To develop and evaluate a multi-path synergic fusion (MSF) deep neural network model for breast mass classification using digital tomosynthesis (DBT). Methods. We retrospectively collected 441 patients who had undergone DBT in which the regions of interest (ROIs) covering malignant/benign were extracted training validation. In proposed MSF framework, three multifaceted representations (gross mass, overview, background) are from ROIs independently processed by multi-scale...