A5019849042- Plant nutrient uptake and metabolism
- Crop Yield and Soil Fertility
- Land Use and Ecosystem Services
- Berry genetics and cultivation research
- Plant Molecular Biology Research
- CRISPR and Genetic Engineering
- Plant Virus Research Studies
- Cytomegalovirus and herpesvirus research
- Legume Nitrogen Fixing Symbiosis
- Plant Stress Responses and Tolerance
- Plant Genetic and Mutation Studies
- Cocoa and Sweet Potato Agronomy
- Herpesvirus Infections and Treatments
- Soybean genetics and cultivation
- Genetic Mapping and Diversity in Plants and Animals
- Urban Heat Island Mitigation
- Biofuel production and bioconversion
- Agronomic Practices and Intercropping Systems
- Environmental Quality and Pollution
- interferon and immune responses
- Water Resources and Sustainability
- Viral Infections and Immunology Research
- Plant Micronutrient Interactions and Effects
- Spatial and Panel Data Analysis
- Sugarcane Cultivation and Processing
Sichuan Academy of Agricultural Sciences
2014-2025
Roslin Institute
2021-2024
University of Edinburgh
2021-2024
Wuhan University
2023
Sweetpotato (Ipomoea batatas (L.) Lam.) is the seventh most important crop in world and mainly cultivated for its underground storage root (SR). The genetic studies of this species have been hindered by a lack high-quality reference sequence due to complex genome structure. Diploid Ipomoea trifida closest relative putative progenitor sweetpotato, which considered model including genetic, cytological, physiological analyses.Here, we generated chromosome-scale SR-forming diploid I. var. Y22...
Wheat (Triticum aestivum L.) is a major cereal crop that grown worldwide, and it highly dependent on sufficient N supply. The molecular mechanisms associated with nitrate uptake assimilation are still poorly understood in wheat. In plants, NRT2 family proteins play crucial role NO3- acquisition translocation under limited conditions. However, the biological functions of these genes wheat unclear, especially their roles assimilation.In this study, comprehensive analysis TaNRT2 was conducted...
As one of three essential nutrients, potassium is regarded as a main limiting factor for growth and development in plant. Sweet potato (Ipomoea batatas L.) seven major food crops grown worldwide, both nutrient-rich bioenergy crop. It typical 'K-favoring' crop, the level ion (K+) supplementation directly influences its production. However, little known about transcriptional changes sweet genes under low-K+ conditions. Here, we analyzed transcriptomic profiles roots response to K+ deficiency...
In late 2023, H5N1 high pathogenicity avian influenza (HPAIV) started circulating in dairy cattle the USA. High viral titres were detected milk from infected cows, raising concerns about onwards human infections. Although pasteurisation was shown to effectively inactivate viruses milk, unpasteurised still poses a risk of infection, both occupational exposure dairies and consumption raw milk. We therefore assessed how long could remain infectious for without heat inactivation. examined...
DNA methylation is a conserved and vital epigenetic modification that plays essential roles in plant growth, development, responses to environmental stress. Cytosine-5 methyltransferases (C5-MTases) demethylases (dMTases) are key regulators of dynamics. However, comprehensive characterization these gene families sweet potato has remained elusive. In this study, we systematically identified analyzed eight C5-MTase five dMTase genes the genomes diploid (Ipomoea trifida, 2n = 2x 30)...
The advances in gene editing bring unprecedented opportunities high throughput functional genomics to animal research. Here we describe a genome wide CRISPR knockout library, btCRISPRko.v1, targeting all protein coding genes the cattle genome. Using it, conducted screens during Bovine Herpes Virus type 1 (BoHV-1) replication and compiled list of pro-viral anti-viral candidates. These candidates might influence multiple aspects BoHV-1 biology such as viral entry, transcription, trafficking...
Abstract Background: Wheat ( Triticum aestivum L.) is a major crop that grown worldwide, but it highly dependent on sufficient N supply. The molecular mechanisms associated with nitrate uptake and assimilation are still poorly understood in wheat. In plants, NRT2 family proteins play crucial role NO 3 – acquisition translocation under limited conditions. However, the biological functions of these genes wheat unclear, especially their roles assimilation. Results: this study, comprehensive...
Bovine herpesvirus type 1 (BoHV-1) causes severe diseases in bovine species and great economic burden to the cattle industry worldwide. Due its complex life cycle, many host factors that affect BoHV-1 replication remain be explored. To understand possible roles Oct1 cellular protein could play this process, we first created Oct1-deficient MDBK cells using CRISPR/Cas9-mediated genome editing. Upon infection, absence of significantly impacted replication, a phenotype rescued by over-expressing...
DNA methylation, a highly conserved epigenetic modification, plays an essential role in regulating gene expression and maintaining genome stability. Aberrations methylation patterns can significantly disrupt plant developmental processes, often leading to abnormal phenotypes. These states are governed by dynamic interplay of de novo maintenance active demethylation, mediated suite specialized enzymes operating under distinct regulatory pathways. This review explores the multifaceted roles...
DNA methylation, an evolutionarily conserved epigenetic mechanism, is crucial for controlling gene activity and ensuring genomic integrity. Altered methylation patterns can profoundly affect plant development, often resulting in atypical phenotypes. The regulation of these states relies on the coordinated actions de novo maintenance, active demethylation, orchestrated by specialized enzymes within distinct pathways. This review delves into diverse roles plants, offering in-depth analysis...
Abstract Background: Potassium is one of the three essential nutrients and regarded as a main limited factor for growth development in plant. Sweet potato ( Ipomoea batatas L.) seven major food crops grown worldwide, it both nutrient-rich bioenergy crop. typical “K-favoring” crop, level potassium ion (K + ) supplementation directly influences its production. However, little known about transcriptional changes sweet genes under low-K condition. To uncover effect stress, we analyzed...
Hexaploid Ipomoea trifida ( I.trifida ), a wild relative of sweetpotato[ batatas (L.) Lam.], has plentiful superior genes and variety anti-adversity characteristics genetically, used as distant hybridization materials in sweetpotato breeding. However, insufficient transcriptomic genomic resources hexaploid are available for understanding the molecular mechanism underlying drought tolerance. In this study, we first to report reference transcriptome using leaf, stem root tissues under...