A5100686816- Neurobiology and Insect Physiology Research
- Insect-Plant Interactions and Control
- Insect Resistance and Genetics
- Insect and Pesticide Research
- Insect and Arachnid Ecology and Behavior
- Insect Utilization and Effects
- Insect Pest Control Strategies
- Insect behavior and control techniques
- Invertebrate Immune Response Mechanisms
- Aquaculture disease management and microbiota
- Plant Virus Research Studies
- Entomopathogenic Microorganisms in Pest Control
- Viral Infectious Diseases and Gene Expression in Insects
- Aquaculture Nutrition and Growth
- Insect symbiosis and bacterial influences
- Forest Insect Ecology and Management
- Plant biochemistry and biosynthesis
- Identification and Quantification in Food
- Plant and animal studies
- Biochemical Analysis and Sensing Techniques
- Fish Biology and Ecology Studies
- Genomics and Phylogenetic Studies
- CRISPR and Genetic Engineering
- Mosquito-borne diseases and control
- Insect Pheromone Research and Control
Murdoch University
2017-2025
Fujian University of Traditional Chinese Medicine
2024
Tongren Hospital
2024
Shanghai Jiao Tong University
2024
Shandong Provincial QianFoShan Hospital
2023
Shandong First Medical University
2023
Shandong Academy of Pharmaceutical Sciences
2023
Jilin Agricultural University
2007-2023
Chinese Academy of Fishery Sciences
2008-2023
Second Military Medical University
2023
Helicoverpa armigera and zea are major caterpillar pests of Old New World agriculture, respectively. Both, particularly H. armigera, extremely polyphagous, has developed resistance to many insecticides. Here we use comparative genomics, transcriptomics resequencing elucidate the genetic basis for their properties as pests.
Emergence of polyphagous herbivorous insects entails significant adaptation to recognize, detoxify and digest a variety host-plants. Despite its biological practical importance - since eat 20% crops no exhaustive analysis gene repertoires required for adaptations in generalist insect herbivores has previously been performed. The noctuid moth Spodoptera frugiperda ranks as one the world's worst agricultural pests. This is while majority other lepidopteran are specialist. It consists two...
Abstract We present the 1.06 Gb sequenced genome of Gastrodia elata , an obligate mycoheterotrophic plant, which contains 18,969 protein-coding genes. Many genes conserved in other plant species have been deleted from G . genome, including most those for photosynthesis. Additional evidence influence plasticity adaptation this lifestyle is evident large number gene families that are expanded glycoside hydrolases and urease likely facilitate digestion hyphae expanded, as associated with...
Abstract The proper regulation of transcription is essential for maintaining genome integrity and executing other downstream cellular functions 1,2 . Here we identify a stable association between the genome-stability regulator sensor single-stranded DNA (SOSS) 3 Integrator-PP2A (INTAC) 4–6 Through SSB1-mediated recognition DNA, SOSS–INTAC stimulates promoter-proximal termination attenuates R-loops associated with paused RNA polymerase II to prevent R-loop-induced instability....
Synthetic mosquito oviposition attractants are sorely needed for surveillance and control programs Culex species, which major vectors of pathogens causing various human diseases, including filariasis, encephalitis, West Nile encephalomyelitis. We employed novel conventional chemical ecology approaches to identify potential attractants, were demonstrated in field tests be effective monitoring populations Cx. p. quinquefasciatus dwellings. Immunohistochemistry studies showed that an...
Scope This study investigates the ability of preterm milk exosomes to survive gastric/pancreatic digestion, internalization by intestinal epithelia, and microRNAs (miRNAs) contents. Methods results At average infant age 1 week 6 days, is collected from mothers who delivered term infants ( n = 10). Milk exposed conditions simulating gut digestion. Exosomes are isolated lysed, miRNAs sequenced. Preterm in vitro can be taken up epithelia. Three hundred thirty identified as exosome miRNAs,...
Culex mosquitoes introduce the pathogens responsible for filariasis, West Nile virus, St. Louis encephalitis, and other diseases into humans. Currently, traps baited with oviposition semiochemicals play an important role in detection efforts could provide environmentally friendly approach to controlling their populations. The odorant binding proteins (OBPs) female's antenna a crucial, if yet imperfectly understood, sensing cues. Here, we report X-ray crystallography NMR 3D structures of OBP1...
Abstract The Insect taste system plays a central role in feeding behaviours and co-evolution of insect-host interactions. Gustatory receptors form the interface between insect environment. From genome transcriptome sequencing we identified 197 novel gustatory receptor (GR) genes from polyphagous pest Helicoverpa armigera . These GRs include significantly expanded bitter family (180 GRs) that could be further divided into three categories based on polypeptide lengths, gene structure amino...
Abstract Although many studies on lepidopteran pheromone‐binding proteins ( PBPs) / general odorant‐binding GOBPs) have been reported, the functional differentiation within and between two protein OBP) subclasses is still elusive. Here we conducted a comparative study three S exi PBP s GOBP in podoptera exigua . Results showed that all five SexiPBP genes same intron numbers conserved exon/intron splice sites. Reverse transcription PCR results these GOBPs were primarily expressed antennae of...
Whey proteins and caseins in breast milk provide bioactivities also have different amino acid composition. Accurate determination of these two major protein classes provides a better understanding human composition function, further aids developing improved infant formulas based on bovine whey caseins. In this study, we implemented LC-MS/MS quantitative analysis iBAQ label-free quantitation, to estimate absolute concentrations α-casein, β-casein, κ-casein samples (n = 88) collected between...
Background The yellow fever mosquito, Aedes aegypti, is the primary vector for viruses that cause fever, mostly in tropical regions of Africa and parts South America, human dengue, which infects 100 million people yearly tropics subtropics. A better understanding structural biology olfactory proteins may pave way development environmentally-friendly mosquito attractants repellents, ultimately contribute to reduction biting disease transmission. Methodology Previously, we isolated cloned a...
Chemosensory receptors including olfactory (ORs), gustatory (GRs) and ionotropic (IRs) play a central role in sensing chemical signals guiding insect behaviours, are potential target genes pest control. The cotton bollworm Helicoverpa armigera is one of the most destructive species that can feed on over 200 different plant species. This diversity host plants likely linked to complex chemosensory system. Here we built previous work characterize crucial tissues environmental interactions...
Helicoverpa armigera (Hübner) is one of the most polyphagous and cosmopolitan pest species, larvae which feed on numerous important crops. The gustatory system critical in guiding insect feeding behavior. Here, we identified a receptor from H. armigera, HaGR9, shows high levels identity to DmGR43a Drosophila melanogaster BmGR9 Bombyx mori. Reverse transcriptase PCR (RT-PCR) revealed HaGR9 highly expressed larval foregut, with little or no expression other chemosensory tissues. Membrane...
The navel orangeworm, Amyelois transitella (Walker), is an agricultural insect pest that can be controlled by disrupting male−female communication with sex pheromones, a technique known as mating disruption. Insect pheromone-binding proteins (PBPs) provide fast transport of hydrophobic pheromones through the aqueous sensillar lymph and promote sensitive delivery to receptors. Here we present three-dimensional structure PBP from A. (AtraPBP1) in solution at pH 4.5 determined nuclear magnetic...
Abstract The Oriental tobacco budworm ( H elicoverpa assulta ) is a specialist herbivore moth and its larvae feed on Solanaceous plants. Z )‐9‐hexadecenal 9‐16: A ld) the major sex pheromone component in . but specific receptor PR against Ald has not yet been identified. In present study, we integrated transcriptomic, bioinformatic functional characterization approaches to investigate chemosensory genes of We identified seven potential PRs with 44 olfactory receptors, 18 gustatory receptors...