A5103023308- Malaria Research and Control
- Mosquito-borne diseases and control
- Insect Pest Control Strategies
- Insect Resistance and Genetics
- Agriculture and Rural Development Research
- African Botany and Ecology Studies
- Parasites and Host Interactions
- Travel-related health issues
- Prenatal Screening and Diagnostics
- Zoonotic diseases and public health
- Parasite Biology and Host Interactions
- Genomics and Rare Diseases
- Yersinia bacterium, plague, ectoparasites research
- Fish Biology and Ecology Studies
- Species Distribution and Climate Change
- Vector-borne infectious diseases
- BRCA gene mutations in cancer
- Vibrio bacteria research studies
- Viral Infections and Vectors
- Biomedical Ethics and Regulation
- Identification and Quantification in Food
Institut Pasteur de Madagascar
2019-2024
Institut Pasteur de la Guyane
2008-2022
Institut Pasteur
2010
Institut de Médecine Tropicale du Service de Santé des Armées
2006
Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale
2005
Institut de Recherche pour le Développement
2005
French Guiana is one of the areas in South America most affected by malaria and where disease has become a serious public health problem. In spite this situation, little recent entomological data are available from main localities occurs, even though they crucial for development an effective vector control strategy. A longitudinal survey was carried out March 2000-February 2002 three Amerindian villages, namely Twenké, Taluène Cayodé, located Amazonian forest Upper-Maroni area, to assess...
Malaria is a major health issue in French Guiana. Amerindian communities remain the most affected. A previous study Camopi highlighted predominant role of environmental factors occurrence malaria. However, all parameters involved transmission were not clearly identified. new survey was conducted order to clarify risk for presence malaria cases Camopi.An open cohort children under seven years age set up on basis biologically confirmed period 2001-2009. Epidemiological and observational data...
Polymorphism at nine microsatellite loci was examined to assess the level of genetic differentiation between four Anopheles arabiensis populations from Senegal, high plateau Madagascar, and Reunion Mauritius islands. Eight showed great polymorphism (2-16 alleles/locus) significant revealed all by F- R-statistics, with Fst estimates ranging 0.080 0.215 equivalent Rst values 0.022 0.300. These amounts are discussed in relation geographic distance including large bodies water, history mosquito...
With an Annual Parasite Incidence (API) of 132.1, in the high and moderate risks zones, Maroni area French Guiana has second highest malaria incidence South-America after Guyana (API = 183.54) far above Brazil 28.25). Malaria transmission is occurring despite strong medical assistance active vector control, based on general WHO recommendations. This situation generated by two main factors that are social cultural characteristics this border area, where several ethnic groups living, lack...
Abstract Background Malaria is still a heavy public health concern in Madagascar. Few studies combining parasitology and entomology have been conducted despite the need for accurate information to design effective vector control measures. In Malagasy region of moderate intense transmission both Plasmodium falciparum P. vivax , combined survey malaria two nearby villages. Methods Community-based surveys were villages Ambohitromby Miarinarivo at three time points (T1, T2 T3) during single...
Malaria remains one of the most common vector-borne diseases in world and definition novel control strategies can benefit from modeling transmission processes. However, data-driven models are often difficult to build, as data very incomplete, heterogeneous nature quality, and/or biased. In this context, a knowledge-based approach is proposed build robust general landscape-based hazard index for malaria that tailored Amazonian region. A partial model risk region, based on landscape features...
The National Malaria Control Program (NMCP) in Madagascar classifies Malagasy districts into two malaria situations: the pre-elimination phase and control phase. Indoor residual spraying (IRS) is identified as main intervention means to Central Highlands. However, it involves an important logistical mobilization thus necessitates prioritization of interventions according magnitude risks. Our objectives were map transmission risk develop a tool support Ministry Public Health (MoH) for...
An important vector control program is ongoing to lower the risk of malaria transmission in French military camp Port-Bouët, Abidjan (Côte d'Ivoire). However, some autochthonous cases are regularly suspected. entomological survey was conducted June 2004 assess and evaluate pyrethroid organophosphate resistance vectors. The average mosquito biting rate 178.0 bites per person night. Mosquitoes belonging Anopheles gambiae (Diptera: Culicidae) complex funestus group were collected. An. s.s....
Anopheles arabiensis, together with gambiae sensu stricto, are the most important vectors of human malaria in sub-Saharan Africa. The situation keeps worsening, 1 to 3 million deaths a year, and alternative strategies needed decrease transmission intensity. In this paper, we studied population structure An. arabiensis from three sample sites on remote Indian Ocean island La Réunion. Our results showed strong genetic structuring between populations Réunion, indicating presence barriers gene...
Abstract Precise identification of anopheline species is paramount for incrimination malaria vectors and implementation a sustainable control program. Anopheline mosquitoes are routinely identified morphologically, technique that time-consuming, needs high level expertise, prone to misidentifications especially when considering Amazonian species. The aim this study was therefore develop DNA-based supplement traditional morphological methods the discrimination collected in French Guiana....
Abstract Background Malaria is still a heavy public health concern in Madagascar. Few studies combining parasitology and entomology have been recently conducted despite the need for such information to design proper vector control measures. In region of moderate intense transmission both Plasmodium falciparum vivax , we combined survey two nearby villages, across malaria season from December 2016 April 2017. Methodology/Principal findings Community-based surveys were close by villages at...
Abstract In French Guiana, the malaria, a parasitic infection transmitted by Anopheline mosquitoes, remains disease of public health importance. To prevent malaria transmission, main effective way Anopheles control. For an control, accurate species identification is indispensable to distinguish vectors from non-vectors. Although, morphological and molecular methods are largely used, innovative tool, based on protein pattern comparisons, Matrix Assisted Laser Desorption / Ionization...
Abstract Anopheles coustani has long be recognized as a secondary malaria vector in Africa. It recently been involved the transmission of both Plasmodium falciparum and vivax Madagascar. As most vector, An. is mainly biting outdoor, which renders control this mosquito species difficult by classical measures use bed nets or indoor residual spraying insecticides. The absence colony hinders better understanding its biology competence towards development adapted strategies. Here, we report first...
Anopheles darlingi is the main vector of malaria in South America. In French Guiana, transmission occurs inland and along rivers with a regular reemergence lower Oyapock area. Control against vectors includes indoor residual spraying deltamethrin distribution long-lasting impregnated bednets. this context, level resistance to pyrethroids was monitored for 4 years using CDC bottle tests An. populations. A loss susceptibility recorded 30-minute knock-down measured as low 81%. However, no...