A5001310642- Microfluidic and Bio-sensing Technologies
- Microfluidic and Capillary Electrophoresis Applications
- Acoustic Wave Resonator Technologies
- Biosensors and Analytical Detection
- Acoustic Wave Phenomena Research
- Music Technology and Sound Studies
- Speech and Audio Processing
- Smart Agriculture and AI
- Electrowetting and Microfluidic Technologies
- Inhalation and Respiratory Drug Delivery
- Breastfeeding Practices and Influences
- Cleft Lip and Palate Research
- Micro and Nano Robotics
- Oral and Craniofacial Lesions
Philips (Netherlands)
2021
University of Glasgow
2010-2014
Ultrasonics offers the possibility of developing sophisticated fluid manipulation tools in lab-on-a-chip technologies. Here we demonstrate ability to shape ultrasonic fields by using phononic lattices, patterned on a disposable chip, carry out complex sequence fluidic manipulations required detect rodent malaria parasite Plasmodium berghei blood. To illustrate different that are available us, used acoustic produce rotational vortices mechanically lyse both red blood cells and parasitic...
The development of microfluidic systems is often constrained both by difficulties associated with the chip interconnection to other instruments and limitations imposed mechanisms that can enable fluid movement processing. Surface acoustic wave (SAW) devices have shown promise in allowing samples be manipulated, although designing complex operations involves using multiple electrode transducers. We now demonstrate a simple interface between piezoelectric SAW device disposable chip, patterned...
Phononic crystals are acoustic metamaterials that used to shape fluid droplets by controlling their interaction with waves in a manner tunable the frequency of excitation. By shaping field generated surface (SAWs), precise control over direction and amplitude interfacial jetting sessile drop liquid on non-piezoelectric materials is demonstrated. Detailed facts importance specialist readers published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset....
We establish a powerful new acoustic technique to programme complex fluidic functions such as droplet movement, merging, mixing and concentration, on disposable superstrate.
The diagnosis of infectious diseases in the Developing World is technologically challenging requiring complex biological assays with a high analytical performance, at minimal cost. By using an opto-acoustic immunoassay technology, integrating components commonly used mobile phone technologies, including surface acoustic wave (SAW) transducers to provide pressure driven flow and CMOS camera enable lensfree detection technique, we demonstrate potential produce such assay. To achieve this,...
Abstract One significant challenge in medical diagnostics lies the development of label‐free methods to separate different cells within complex biological samples. Here we demonstrate a generic, low‐power ultrasonic separation technique, able enrich cell types based upon their physical properties. For malaria, differentiate between infected and non‐infected red blood fingerprick‐sized drop blood. We are achieve an enrichment circulating by ring stage parasite over nonparasitized two three...
We demonstrate the use of a phononic crystal to enable nebulisation liquid droplets from low-cost disposable arrays, using surface acoustic waves (SAW). The SAWs were generated interdigitated transducers (IDT) on piezoelectric (LiNbO3) and coupled into structure, referred as superstrate. Using its excellent reflecting properties, structures confined field within superstrate, resulting in concentration energy, manner controllable by excitation frequency. show that this capability mitigates...
Microactuation of free standing objects in fluids is currently dominated by the rotary propeller, giving rise to a range potential applications military, aeronautic and biomedical fields. Previously, surface acoustic waves (SAWs) have been shown be increasing interest field microfluidics, where refraction SAW into drop fluid creates convective flow, phenomenon generally known as streaming. We now show how SAWs, generated at microelectronic devices, can used an efficient method propulsion...
One significant challenge in medical diagnostics lies the development of label-free methods to separate different cells within complex biological samples. Here we demonstrate a generic, low-power ultrasonic separation technique, able enrich cell types based upon their physical properties. For malaria, differentiate between infected and non-infected red blood fingerprick-sized drop blood. We are achieve an enrichment circulating by ring stage parasite over nonparasitized two three orders...
Microfluidic systems have faced challenges in handling real samples and the chip interconnection to other instruments. Here we present a simple interface, where surface acoustic waves (SAWs) from piezoelectric device are coupled into disposable acoustically responsive microfluidic chip. By manipulating droplets, SAW technologies already shown their potential microfluidics, but it has been limited by need rely upon mixed signal generation at multiple interdigitated electrode transducers...
Infectious diseases cause 10 million deaths each year worldwide, accounting for ~60% of all children aged 5- 14. Although these arise primarily through pneumonia, TB, malaria and HIV, there are also the so called "neglected diseases" such as sleeping sickness bilharzia, which have a devastating impact on rural communities, in sub-Sahara Africa. There, demands successful Developing World diagnostic particularly rigorous, requiring low cost instrumentation with power consumption (there is...
Although science established that breastfeeding is the healthiest option for mother and child, most women are not able to breastfeed exclusively first 6 months, as advised by World Health Organization, mainly due infant physical abilities. In fact, it has been shown issues with tongue movements linked problems. However, there a lack of simple use diagnostic tools characterize movement during breastfeeding. this study, we developed an image-processing algorithm aimed at analyzing from...