A5047236122- Medical Imaging Techniques and Applications
- Radioactive element chemistry and processing
- Advanced MRI Techniques and Applications
- Groundwater flow and contamination studies
- CO2 Sequestration and Geologic Interactions
- Hydraulic Fracturing and Reservoir Analysis
- Atomic and Subatomic Physics Research
- Neuroscience and Neuropharmacology Research
- Neurotransmitter Receptor Influence on Behavior
- Advanced X-ray and CT Imaging
- earthquake and tectonic studies
- Seismic Imaging and Inversion Techniques
- Hydrology and Watershed Management Studies
- Radiation Dose and Imaging
- Advanced X-ray Imaging Techniques
- Lichen and fungal ecology
- Biotin and Related Studies
- Soil erosion and sediment transport
- Advanced Neuroimaging Techniques and Applications
- Radioactive Decay and Measurement Techniques
- Mine drainage and remediation techniques
- Lanthanide and Transition Metal Complexes
- Radiopharmaceutical Chemistry and Applications
- Chemical Synthesis and Characterization
- NMR spectroscopy and applications
Lawrence Berkeley National Laboratory
2010-2016
University of Wisconsin–Madison
2005-2012
University of California, San Francisco
2010
HighlY constrained backPRojection (HYPR) is a promising image-processing strategy with widespread application in time-resolved MRI that also well suited for PET applications requiring time series data. The HYPR technique involves the creation of composite image from entire series. individual frames then provide basis weighting matrices composite. signal-to-noise ratio (SNR) can be dramatically improved using high SNR image. In this study, we introduced modified algorithm (the method...
(18)F-Fallypride and (11)C-FLB457 are commonly used PET radioligands for imaging extrastriatal dopamine D(2)/D(3) receptors, but differences in their vivo kinetics may affect the sensitivity measuring subtle changes receptor binding. Focusing on regions of low binding, a direct comparison (18)F-fallypride was made using MI protocol. Injection protocols were designed to estimate K(1), k(2), f(ND)k(on), B(max), k(off) midbrain cortical rhesus monkey. cleared from arterial plasma faster yielded...
We report results of an experimental investigation into the effects small-scale (mm–cm) heterogeneities on solute spreading and mixing in a Berea sandstone core. Pulse-tracer tests have been carried out Péclet number regime $Pe=6{-}40$ are supplemented by unique combination two imaging techniques. X-ray computed tomography (CT) is used to quantify subcore-scale terms permeability contrasts at spatial resolution approximately $10~\text{mm}^{3}$ , while [11C] positron emission (PET) applied...
We demonstrate the utility of nuclear medical imaging technologies and a readily available radiotracer, [99mTc]TcO4–, for noninvasive monitoring Fe(II) production in acetate-stimulated sediments from Old Rifle, CO, USA. Microcosms consisting sediment artificial groundwater media amended with acetate were probed by repeated injection radiotracer over three weeks. Gamma camera was used to noninvasively quantify rate extent [99mTc]TcO4– partitioning solution sediment. Aqueous...
The performance of a SPECT imaging system for vertically oriented glass columns (10 cm diameter x 30 long) has been evaluated in terms spatial resolution, image uniformity, and linearity. This was developed to support research environmental geosciences by determining flow patterns heterogeneous porous media (e.g., sediment) through simultaneous monitoring sediment chemistry parameters. Using Derenzo-like hot-rod phantom, rods down 7.9 mm were resolved. Flood images had an integral uniformity...
Biological soil crusts (BSCs) are critical contributors to the biogeochemistry of ecosystems in arid and semi-arid regions worldwide. Photosynthetic microorganisms such as cyanobacteria often predominant primary producers, fixing both carbon nitrogen producing polysaccharides that aid stabilization. Here, we exposed BSCs 11CO2 quantified spatial distribution fixation on a millimeter scale using positron emission tomography (PET). These experiments showed live fixed up 20 times more than...
In an effort to more quickly evaluate the conditioning of our 18F-fluorine target and determine amount F2 that is released with each unload, a simple spectrophotometer was fabricated aids in quantifying I2 produced as result bubbling gas into solution potassium iodide. A narrow range LED (470 ± 10 nm), combined wide photodiode (320-1100 nm) were used construct device. We able use this device quantitate obtained good correlation (R2>0.991) values by "traditional" titration method.
This paper describes the modifications made to a BioRad EM-1 UV detector for use in radioactive material handling hot cell. A 5m cable has been built allow control unit remain outside of cell while optics resides inside USB data acquisition and device also added unit, allowing PC instrument reading signals without need choose pre-determined absorbance range, maximizing dynamic range measured absorbance.
This paper presents imaging and modeling aspects of an interdisciplinary study subsurface pollution environmental remediation. F18 — FDG PET Tc99m NaTcO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</inf> SPECT studie s were performed to follow dynamic changes in the radiotracer distribution model systems. Radioisotope solution was pumped through test columns filled with sand or sediment order reproduce conditions groundwater flow satu rated...