A5001167426- Bee Products Chemical Analysis
- melanin and skin pigmentation
- Silymarin and Mushroom Poisoning
- Neuropeptides and Animal Physiology
- Drug Transport and Resistance Mechanisms
- Wound Healing and Treatments
- Liver Disease and Transplantation
- Biochemical Analysis and Sensing Techniques
- Skin Protection and Aging
- Mesenchymal stem cell research
- Phosphodiesterase function and regulation
- Nitric Oxide and Endothelin Effects
- Garlic and Onion Studies
- Advanced ceramic materials synthesis
- Drug-Induced Hepatotoxicity and Protection
- Carbon Nanotubes in Composites
- Fiber-reinforced polymer composites
- Phytochemicals and Antioxidant Activities
- Toxoplasma gondii Research Studies
- Ginger and Zingiberaceae research
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects of Natural Compounds
- Nanoparticles: synthesis and applications
- Sperm and Testicular Function
- Sulfur Compounds in Biology
Ministry of Health and Medical Education
2011-2024
Iran Nanohealth Committee Food and Drug Organization
2014-2022
Islamic Azad University Saveh
2019-2022
Islamic Azad University, Science and Research Branch
2014-2018
Islamic Azad University Pharmaceutical Sciences Branch
2016
Ministry of Health
2003-2012
Tarbiat Modares University
2011
Ministry of Health of the Russian Federation
2010
Ministero della Salute
2010
Shahid Beheshti University of Medical Sciences
2000-2002
Granisetron, a serotonin 5-HT3 receptor antagonist, widely used as an antiemetic drug following chemotherapy, has been found to improve learning and memory. In this study, effects of granisetron on spatial recognition memory fear the involvement nitric oxide (NO) have determined in Y-maze passive avoidance test. Granisetron (3, 10 mg/kg, intraperitoneally) was administered scopolamine-induced memory-impaired mice prior acquisition, consolidation retrieval phases, either presence or absence...
Context: Silymarin, a flavonolignan from Silybum marianum (L.) Gaertn. (Asteraceae), has been reported to have antioxidant and anti-inflammatory properties. Therefore, it may be worthwhile study the effect of silymarin on wound healing.Objective: To evaluate human fibroblast cells in an vitro model healing.Materials methods: Human were treated with different concentrations (4.5, 9, 18, 36 µg/mL) silymarin. The effects cell viability, proliferation, collagen synthesis, expression...
A variety of recombinant protein expression systems have been developed for heterologous genes in both prokaryotic and eukaryotic such as bacteria, yeast, mammals, insects, transgenic animals plants. Also, it has reported that Leishmania tarentolae, a trypanosomatid protozoan parasite the white-spotted wall gecko (Tarentola annularis), capability expressing genes. Trypanosomatidae are rich glycoproteins, which can account more than 10% total protein. The oligosaccharide structures their...
Background: Worldwide, breast cancer is the most common diagnosed among women and a leading cause of deaths. The age onset in Iran has become reduced by decade for unknown reasons. Herceptin, humanized monoclonal antibody, target therapy cells with over expression HER2-neu receptors, but it an expensive drug only 20% beneficial rate survival. This study introduces novel approach to enhance efficacy this through immunoconjugation antibody botulinum toxin. Decreasing cost adverse effects were...
Tyrosinase plays a pivotal role in the hyperpigmentation and enzymatic browning of fruit vegetable. Therefore, tyrosinase inhibitors can be interest industries as depigmentation compounds well anti-browning agents. In present study, series chlorophenylquinazolin-4(3H)-one derivative were rationally designed synthesized. The formation target was confirmed by spectral characterization techniques such IR, 1 H-NMR, 13 C-NMR, elemental analysis. Among synthesized derivatives, compound 8l proved...
The rate and degree of subsensitivity development to morphine (mu-opioid receptor, preferred, but not selective agonist) U50488H (highly kappa-opioid receptor were assessed in vitro on guinea pig ileum (GPI) cholestatic animals 2, 5, 7 days after bile duct ligation. In addition this phenomenon morphine, the effects SNC 80 delta-opioid studied mice vas deferens (MVD) 7, 10, 15 IC(50) for each compound was determined these preparations. ratio duct-ligated sham control provides a quantitative...
Toxoplasma gondii is a widespread protozoan parasite that infects broad range of warm blooded animals as well humans. The present study was investigated to evaluate the effects allium cepa on renal failur in male rats which experimentally infected by gondii, RH strain.Wistar rat (n=40) were allocated into four groups, group one received tachyzoites T. (ip) (n=10), two (ip), plus fresh onion juice gavages method three just (n=10) and control nothing. Animals kept standard condition. In 30 day...
All organisms require an equivalent source for living. Reduced glutathione is the most abundant thiol containing protein in mammalian cells and organs. Glutathione was discovered by Hopkins 1924 who published his findings JBC. It a three peptide glutamic acid, cystein glycin found reduced oxide forms cell. High concentration of its high reduced/oxide potential makes GSH powerful antioxidant first defense line against free radicals. However, efficient tool detoxification xenobiotic. In...