A5012045686- Meningioma and schwannoma management
- Glioma Diagnosis and Treatment
- Chromatin Remodeling and Cancer
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Hearing, Cochlea, Tinnitus, Genetics
- Vestibular and auditory disorders
- Moyamoya disease diagnosis and treatment
- Teratomas and Epidermoid Cysts
- Folate and B Vitamins Research
- Cancer Genomics and Diagnostics
- Ear and Head Tumors
- Fetal and Pediatric Neurological Disorders
Fondazione IRCCS Istituto Neurologico Carlo Besta
1995-2024
Abstract Background We applied the strategy for M+ medulloblastoma across all high-risk subgroups, including LC/A histology, TP53 mutations, and MYC/MYCN amplification. Methods Patients over 3 years old received, after surgery, staging histo-biological analysis, sequential high-dose-methotrexate(HD-MTX), high-dose-etoposide(HD-VP16), high-dose-cyclophosphamide(HD-Cyclo), high-dose-carboplatin(HD-Carbo). Hyperfractionated-accelerated-radiotherapy–craniospinal(HART-CSI), administered twice...
Neurofibromatosis type-1 (NF1) is a monogenic tumor-predisposition syndrome creating wide variety of cognitive and behavioral abnormalities, such as decrease in functioning, deficits visuospatial processing, attention, social functioning. NF1 patients are at risk to develop neurofibromas other tumors, optic pathway gliomas tumors the central nervous system. Few studies have investigated impact an additional diagnosis brain tumor on outcome children with NF1, showing unclear results without...
The time course of socio-communicative disturbances in children after posterior fossa tumor resection is variable clinical reports, and its assessment may help to understand the role cerebellum pathogenesis disorders improve rehabilitation plans. We report 3-year cognitive-behavioral follow-up a female patient (LZ) who underwent surgical ablation vermis due medulloblastoma at age 9. LZ developed severe post-operative Cerebellar Cognitive Affective Syndrome (CCAS) with cognitive-executive...
Elevati livelli di omocisteinemia hanno un effetto citotossico sull'endotelio vasale e interagiscono con le piastrine proteine della coagulazione in senso pro-aggregante. Numerosi deficit enzimatici congeniti del metabolismo metionina possono causare elevati omocisteina nel plasma determinare numerose sindromi cliniche dell'omocistinuria associate frequentemente a lesioni vascolari ischemiche bambino giovane adulto. Anche una lieve iperomocisteinemia, causata da folati, vitamina B12 o B6...