A5049718133- Complex Network Analysis Techniques
- Opinion Dynamics and Social Influence
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Social and Intergroup Psychology
- Social Capital and Networks
- Statistical Methods and Bayesian Inference
- Mental Health Research Topics
- Opioid Use Disorder Treatment
- Health disparities and outcomes
- Homelessness and Social Issues
- Sex work and related issues
- Community Health and Development
- Data Analysis with R
- demographic modeling and climate adaptation
- Frailty in Older Adults
- Pituitary Gland Disorders and Treatments
- Palliative Care and End-of-Life Issues
- Breastfeeding Practices and Influences
- Retinoids in leukemia and cellular processes
- Hormonal Regulation and Hypertension
- Digital Marketing and Social Media
- Urban, Neighborhood, and Segregation Studies
- Adrenal Hormones and Disorders
- Cell death mechanisms and regulation
Duke University
1994-2021
University of Michigan
2017-2021
Social Science Research Council
2021
Deutsche Bank (Germany)
2018
Antibodies to neuropeptide receptors can be used localize and characterize the in tissues cell lines. Two strategies were study rat substance P receptor (SPR, NK-1) by immunological methods. First, a polyclonal antiserum was raised immunizing rabbits with peptide corresponding 15 amino acid residues (KTMTESSSFYSNMLA, SPR393-407) at intracellular C-terminus of SPR coupled bovine thyroglobulin. An obtained titer for half-maximal binding 125I-SPR393-407 1:70,000. Nonradioactive SPR393-407...
We compare the performance of multiple respondent-driven sampling estimators under different sample recruitment conditions in hidden populations female sex workers midst China's ongoing epidemic sexually transmitted infections. first examine empirically calibrated simulations grounded survey data to evaluate relative each estimator ideal consistent with assumptions and that mimic observed processes. One estimator, which incorporates respondents' reports on their network contacts,...
Significance A major focus of social network analysis is attempting to find central “influencers” or “opinion leaders” who can hasten slow the spread a contagion. Using simulation, we demonstrate that most node important only under conventional but implausible scope conditions. We model introduction mass media advertising and show this allows contagions equally fast whether not seed highly network. The loses its relative importance even if influence extremely weak. This implies that, rather...
Respondent-driven sampling (RDS) is a popular method for hard-to-survey populations that leverages social network connections through peer recruitment. Although RDS most frequently applied to estimate the prevalence of infections and risk behaviors interest public health, such as HIV/AIDS or condom use, it rarely used draw inferences about structural properties networks among because does not typically collect necessary data. Drawing on recent advances in computer science, authors introduce...
Prevailing social network frameworks examine the association between peer ties and behaviors, such as smoking, but role of isolates is poorly understood. Some theories predict isolated adolescents are protected from influence that increases while others suggest more likely to initiate smoking because they lack control provided by friendships. Building on a growing literature seeks explain these contradictions moving beyond homogeneous understanding isolation, we identify relationship three...
Virtually all social diffusion work relies on a common formal basis, which predicts that consensus will develop among connected population as the result of diffusion. In spite popularity models predict consensus, few empirical studies examine or clustering attitudes, directly. The do either focus coordinating role strict hierarchies, results online experiments, and not consider how occurs groups in situ. This study uses longitudinal data adolescent networks to show meso-level structures,...
Social networks represent two different facets of social life: (1) stable paths for diffusion, or the spread something through a connected population, and (2) random draws from an underlying space, which indicate relative positions people in network to one another. The dual nature creates challenge: if observed ties are single draw, is it realistic expect that diffusion only follows ties? This study takes first step toward integrating these perspectives by introducing space model. In model,...
Respondent-driven sampling (RDS) is an increasingly popular chain-referral method. Although it has proved effective at generating samples of hard to reach populations—meaning populations for which frames are not available because they hidden or socially stigmatized like sex workers injecting drug users—quickly and cost-effectively, the ease collecting sample comes with a cost: bias inefficiency in estimates population parameters (Gile & Handcock, 2010; Goel Salganik, 2010). One way that...
Clustering coefficient estimation in respondent-driven sampling
Prevailing social network frameworks examine the association between peerties and behaviors like smoking, but role of isolates is poorlyunderstood. Some theories predict isolated adolescents are protected frompeer influence that increases while others suggest aremore likely to initiate smoking because they lack control providedby peer friendships. Building on a growing literature seeks explainthese contradictions by moving beyond homogeneous understanding ofisolation, we identify...
In this issue, Kindel et al. describe a new approach to managing survey data in service of the Fragile Families Challenge, which they call “treating metadata as data.” Although present is good first step, more ambitious proposal could improve analysis even substantially. The author recommends that collection efforts distribute an open-source set tools for working with particular calls data-specific functions. goal these functions codify best practices commonly used statistical software....
Virtually all social diffusion work relies on a common formal basis, whichpredicts that consensus will develop among connected population as theresult of diffusion. In spite the popularity modelsthat predict consensus, few empirical studies examine or aclustering attitudes, directly. Those do either focus thecoordinating role strict hierarchies, results onlineexperiments, and not consider how occurs groups in situ.This study uses longitudinal data adolescent networks to show howmeso-level...
A 65 year old woman with long-standing Addison's disease treated oral glucocorticoid and mineralocorticoid replacement had persistently high ACTH levels, inadequate suppression of on low-dose dexamethasone, sellar enlargement, pigmentation, thus resembled patients alleged to develop corticotropinomas while for adrenal insufficiency. Since animal studies suggested that rapid rises corticosteroids within the physiologic range can inhibit release, we administered brief infusions cortisol every...
Respondent-driven sampling (RDS) is a popular method for hard-to-survey populations that leverages social network connections through peer recruitment. While RDS most frequently applied to estimate the prevalence of infections and risk behaviors interest public health, like HIV/AIDS or condom use, it rarely used draw inferences about structural properties networks among such because does not typically collect necessary data. Drawing on recent advances in computer science, we introduce set...
Virtually all social diffusion work relies on a common formal basis, whichpredicts that consensus will develop among connected population as theresult of diffusion. In spite the popularity modelsthat predict consensus, few empirical studies examine or aclustering attitudes, directly. Those do either focus thecoordinating role strict hierarchies, results onlineexperiments, and not consider how occurs groups in situ.This study uses longitudinal data adolescent networks to show howmeso-level...
Clustering coefficient estimation in respondent-driven sampling
Prevailing social network frameworks examine the association between peerties and behaviors like smoking, but role of isolates is poorlyunderstood. Some theories predict isolated adolescents are protected frompeer influence that increases while others suggest aremore likely to initiate smoking because they lack control providedby peer friendships. Building on a growing literature seeks explainthese contradictions by moving beyond homogeneous understanding ofisolation, we identify...
We have previously identified calpains as important modulators of AML1/MTG8-dependent leukaemogenesis. Like caspases and cathepsins, belong to the family cysteine proteases. By application protease inhibitors siRNAs we investigated individual proteases essential for leukaemic growth, maintenance progression.