A5041886510- Enzyme-mediated dye degradation
- Biochemical and biochemical processes
- Lignin and Wood Chemistry
- Natural Fiber Reinforced Composites
- Analytical Chemistry and Chromatography
- Biological Activity of Diterpenoids and Biflavonoids
- Plant Gene Expression Analysis
- Wood Treatment and Properties
- Pharmaceutical and Antibiotic Environmental Impacts
- Plant-derived Lignans Synthesis and Bioactivity
- Microbial Metabolism and Applications
- Legume Nitrogen Fixing Symbiosis
- Enzyme Production and Characterization
- Microbial Metabolic Engineering and Bioproduction
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Plant biochemistry and biosynthesis
- Natural product bioactivities and synthesis
- Dye analysis and toxicity
- Embedded Systems Design Techniques
- Synthesis and Reactions of Organic Compounds
- Biofuel production and bioconversion
- Spine and Intervertebral Disc Pathology
- Fermentation and Sensory Analysis
- Oral microbiology and periodontitis research
- Environmental Toxicology and Ecotoxicology
Keio University
2020-2025
Tokyo University of Agriculture and Technology
1993-2024
Shizuoka University
2006-2024
Keio University Shonan Fujisawa
2020
Ryukoku University
2020
Yokohama Rosai Hospital
2019
Yokohama City University
2019
Yokohama City University Medical Center
2019
Kanagawa Prefectural Hospital Organization
2019
Chigasaki Rehabilitation College
2019
Few studies have been conducted on patterns of recurrence after resection for distal cholangiocarcinoma (DCC). The aim this study was to investigate the incidence and pattern DCC, evaluate prognostic factors time recurrence-free survival (RFS).Patients who underwent pancreatoduodenectomy with curative intent DCC between 2001 2010 at one 30 hospitals in Japan were reviewed retrospectively, special attention patterns. Cox proportional hazards model used multivariable analysis.In interval, 389...
Peroxidase/H2O2-mediated radical coupling of 4-hydroxycinnamaldehydes produces 8–O–4-, 8–5-, and 8–8-coupled dehydrodimers as has been documented earlier, well the 5–5-coupled dehydrodimer. The 8–5-dehydrodimer is however produced kinetically in its cyclic phenylcoumaran form at neutral pH. Synthetic polymers from mixtures hydroxycinnamaldehydes normal monolignols provide next level complexity. Spectral data dimers, oligomers, synthetic have allowed a more substantive assignment aldehyde...
Vol. 62, no. 10, p. 3684, column 2, line 16: "Tri(methylsilyl)" should read "Tri(trimethylsilyl)." Line 17: "Di(methylsilyl)" "Di(trimethylsilyl)." 20: "Trimethylsilyl." Page 3686, 1, reference 12: The journal be Dokl. Akad. Nauk Belarusi. [This corrects the article on 3679 in vol. 62.].
Many ligninolytic fungi appear to lack lignin peroxidase (LiP), the enzyme generally thought cleave major, recalcitrant, nonphenolic structures in lignin. At least one such fungus, Ceriporiopsis subvermispora, is nevertheless able degrade these structures. Experiments showed that wood block cultures and defined liquid medium of C. subvermispora rapidly depolymerized mineralized a (sup14)C-labeled, polyethylene glycol-linked, high-molecular-weight (beta)-O-4 model compound (model I)...
It was found that 2,4‐di( tert ‐butyl)‐4‐(methoxycarbonylmethyl)‐2‐buten‐4‐olide (II) formed as an aromatic ring cleavage product of a phenolic lignin model compound, 4,6‐di( ‐butyl)guaiacol (I), by laccase Coriolus versicolor . Based on isotopic experiments with 18 O 2 H O, the mechanism formation II from I is discussed.
Weexamined the distribution of mercury and selenium in fifteen tissues striped dolphins (Stenella coeruleoalba). The total level mature showeddifferences among was highest liver. concentration most increased with age, reached a constant at 20 to 25 years age. not appreciably different males, pregnant females, lactating females resting females. In muscle individuals, collected 1977 1980 higher than that those 1978 1979. Methylmercury showed less variation amongthe tissues. ratio methylmercury...
Effective household hygiene measures require that sources of bacterial contamination and the places to which spreads be carefully identified. Therefore, a study was performed examine distribution microorganisms throughout ordinary households in Japan, has its own unique customs daily life food preparation.Using stamping method, samples were taken from 100 different items each 86 households. This found kitchens/dining rooms have greatest level microbial bathrooms, next highest level. Toilets...
Abstract Background Little is known about the value of portal vein (PV) resection in distal cholangiocarcinoma. The aim this study was to evaluate clinical significance PV Methods Patients who underwent pancreatoduodenectomy (PD) for cholangiocarcinoma between 2001 and 2010 at one 31 hospitals Japan were reviewed retrospectively with special attention resection. Short- long-term outcomes evaluated. Results In interval, 453 consecutive patients PD, whom (6·8 per cent) had combined duration...
The structure and function of the N-linked carbohydrate chains in laccase III, one ligninolytic glycoenzymes from white-rot fungus Coriolus versicolor, have been partially characterized using endoglycosidases (Endo F Endo H) N-asparagine-specific inhibitor, tunicamycin. In presence 10 μg tunicamycin ml−1 proteinase activities culture filtrates C. versicolor were measured over 3 weeks. Laccase activity was slightly decreased by addition tunicamycin, whereas increased. not necessary for...
A gene for alkaline cellulase from the alkalophilic Bacillus sp. KSM-635 was cloned into HindIII site of pBR322 and expressed in Escherichia coli HB101. Although recombinant plasmid contained two inserts 2.6 kb 4.0 kb, were found to be contiguous genome by hybridization analysis. Nucleotide sequences a 2.4 region which indispensable production cellulase, flanking, 1.1 region, determined. There an open reading frame (ORF) 2823 bp 3498 sequence determined, encoded 941 amino acid residues. Two...
Periodontitis, a chronic inflammatory disease driven by oral microbiota dysbiosis, is associated with systemic diseases; however, the mechanisms remain poorly understood. Using silk-ligation-induced periodontitis mouse model, we investigated changes in microbiota, immune responses, and effects, including respiratory disease. Oral dysbiosis persisted for five weeks was characterized an increased abundance of genera Enterococcus, Proteus, Escherichia_Shigella, decrease Lactococcus. Antibiotic...