A5039949041- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Curcumin's Biomedical Applications
- Nanoplatforms for cancer theranostics
- Characterization and Applications of Magnetic Nanoparticles
- Nanoparticles: synthesis and applications
- Iron oxide chemistry and applications
- Magnetic Properties and Synthesis of Ferrites
- RNA Interference and Gene Delivery
- biodegradable polymer synthesis and properties
- Wastewater Treatment and Nitrogen Removal
- Advanced Drug Delivery Systems
- Polysaccharides and Plant Cell Walls
- Lanthanide and Transition Metal Complexes
- Supramolecular Self-Assembly in Materials
- Advanced Nanomaterials in Catalysis
- Nanomaterials for catalytic reactions
- Nanocomposite Films for Food Packaging
- Microbial Community Ecology and Physiology
- Constructed Wetlands for Wastewater Treatment
- Advanced biosensing and bioanalysis techniques
- Electrospun Nanofibers in Biomedical Applications
- Microplastics and Plastic Pollution
- Microfluidic and Bio-sensing Technologies
- Retinoids in leukemia and cellular processes
Vietnam Academy of Science and Technology
2016-2025
Institute of Materials Science
2012-2024
Hanoi University of Mining and Geology
2022
VNU University of Science
2022
Vietnam National University, Hanoi
2021
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2005
CEA Paris-Saclay
2005
Centre National de la Recherche Scientifique
2005
Theranostics, which is the combination of both therapeutic and diagnostic capacities in one dose, a promising tool for clinical application research. Although there are many chromophores available optical imaging, their applications limited due to photobleaching property or intrinsic toxicity. Curcumin, natural compound extracted from rhizome curcuma longa, well known thanks its bio-pharmaceutical activities strong fluorescence as biocompatible probe bio-imaging. In this study, we aimed...
Silver nanoparticle (AgNP) has a wide range antibacterial effect and is extensively used in different aspects of medicine, food storage, household products, disinfectants, biomonitoring environmental remediation etc. In the present study, we examined growth inhibition engineered silver nanoparticles against bloom forming cyanobacterial M. aeruginosa strain. AgNPs were synthesized by chemical reduction method at room temperature UV–Vis spectroscopy, scanning electron microscopy (SEM),...
(1) Background: Magnetite (Fe3O4) nanoparticles have great potential for biomedical applications, including hyperthermia and magnetic resonance imaging. In this study, we aimed to identify the biological activity of nanoconjugates composed superparamagnetic Fe3O4 coated with alginate curcumin (Fe3O4/Cur@ALG) in cancer cells. (2) Methods: The were evaluated biocompatibility toxicity on mice. MRI enhancement capacities Fe3O4/Cur@ALG determined both vitro vivo sarcoma models. (3) Results:...
Background: Despite medicinal advances, cancer is still a big problem requiring better diagnostic and treatment tools. Magnetic nanoparticle (MNP)-based nanosystems for multiple-purpose applications were developed these unmet needs. Methods: This study fabricated novel trifunctional MNPs of Fe3O4@PLA-PEG drug release, MRI magnetic fluid hyperthermia. Result: The provided significant loading curcumin (∼11%) with controllable release ability, high specific absorption rate 82.2 W/g...
Paclitaxel is one of the most effective chemotherapeutic agents for treating various types cancer. However, clinical application paclitaxel in cancer treatment considerably limited due to its poor water solubility and low therapeutic index. Thus, it requires an urgent solution improve efficacy paclitaxel. In this study, folate decorated loaded PLA-TPGS nanoparticles were prepared by a modified emulsification/solvent evaporation method. The obtained characterized Field Emission Scanning...
Multifunctional nanosystems help to control drug release and highly improve the cancer treatment efficacy in <italic>in vivo</italic> models.
Abstract In this study magnetic fluids were manufactured by the adsorption of chitosan (CS) and O-carboxymethyl (OCMCS) on Fe 3 O 4 nanoparticles to be used as hyperthermic thermoseeds. particles characterized physico-chemical methods such as: thermogravimetry analysis (TGA), x-ray diffraction (XRD), Raman spectrum, Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM) vibrating sample magnetometer (VSM). The SEM images XRD patterns showed that synthesized single...
Doxorubicin (DOX) is one of the most effective anticancer drugs for treating many types cancer. However, clinical applications DOX were hindered because serious side-effects resulting from unselective delivery to cancer cell including congestive heart failure, chronic cardiomyopathy and drug resistance. Recently, it has been demonstrated that loading anti-cancer onto nanosystems helps maximize therapeutic efficiency minimize unwanted via passive active targeting mechanisms. In this study we...
Radiotherapy side-effects present serious problems in cancer treatment. Melanin, a natural polymer with low toxicity, is considered as potential radio-protector; however, its application an agent against irradiation during treatment has still received little attention. In this study, nanomelanin particles were prepared, characterized and applied protecting the spleens of tumor-bearing mice irradiated X-rays. These nanoparticles had sizes varying range 80–200 nm contained several important...
Fe 3 O 4 and Dox do not affect the fluorescence of Cyanine 5.5 A3 conjugate can be effectively used in MR NIR-fluorescence tumor imaging.
Abstract The clinical application of curcumin in cancer treatment is considerably limited due to its serious poor delivery characteristics. In order increase the hydrophilicity and drug capability, we encapsulated into 1,3-β-glucan isolated from Vietnam medicinal mushroom Hericium erinaceum. 1,3-β-glucan-encapsulated nanoparticles (Cur–Glu) were found be spherical with an average size 50 nm, being suitable for applications. They much more soluble water not only than free but also other...
Curcumin (Cur) is a yellow compound isolated from rhizome of the herb curcuma longa. possesses antioxidant, anti-inflammatory, anti-carcinogenic and antimicrobial properties, suppresses proliferation many tumor cells. However, clinical application curcumin in cancer treatment considerably limited due to its serious poor delivery characteristics. In order increase hydrophilicity drug capability, we encapsulated into copolymer PLA-TPGS, 1,3-beta-glucan (Glu), O-carboxymethyl chitosan (OCMCs)...
Abstract This paper presents an overview of syntheses and applications magnetic nanoparticles (MNPs) at the Institute Materials Science, Vietnam Academy Science Technology. Three families oxide MNPs, magnetite, manganite spinel ferrite materials, were prepared in various ways: coprecipitation, sol–gel high energy mechanical milling. Basic properties MNPs characterized by Vibrating Sample Magnetometer (VSM) Physical Properties Measurement Systems (PPMS). As for biomedical application, aim was...
Along with the development of nanotechnology, drug delivery nanosystems (DDNSs) have attracted a great deal concern among scientists over world, especially in cancer treatment. DDNSs not only improve water solubility anticancer drugs but also increase therapeutic efficacy and minimize side effects treatment methods through targeting mechanisms including passive active targeting. Passive is based on nano-size systems while specific bindings between ligands attached unique receptors cell...
The use of naturally occurring materials with antibacterial properties has gained a great interest in infected wound management. Despite being an abundant resource Vietnam, chitosan and its derivatives have not yet been intensively explored for their potential such application. Here, we utilized local source to synthesize oligomers (OCS) using hydrogen peroxide (H