A5026271184- Nanoparticle-Based Drug Delivery
- Dendrimers and Hyperbranched Polymers
- Hydrogels: synthesis, properties, applications
- Advanced Drug Delivery Systems
- Electrospun Nanofibers in Biomedical Applications
- RNA Interference and Gene Delivery
- Wound Healing and Treatments
- Bone Tissue Engineering Materials
- Polymer Surface Interaction Studies
- 3D Printing in Biomedical Research
- Nanoplatforms for cancer theranostics
- Silk-based biomaterials and applications
- Nanoparticles: synthesis and applications
- Curcumin's Biomedical Applications
- Graphene and Nanomaterials Applications
- Advanced Polymer Synthesis and Characterization
- Supramolecular Self-Assembly in Materials
- Advanced Nanomaterials in Catalysis
- Concrete Corrosion and Durability
- Cell Adhesion Molecules Research
- Nanocomposite Films for Food Packaging
- Ferrocene Chemistry and Applications
- Corrosion Behavior and Inhibition
- biodegradable polymer synthesis and properties
- Quantum Dots Synthesis And Properties
Vietnam Academy of Science and Technology
2016-2025
Lentigen Technology (United States)
2024-2025
Ho Chi Minh City University of Science
2010-2025
Ho Chi Minh City University of Technology
2019-2023
Hanoi University of Science and Technology
2022
The Vietnam National Institute of Educational Sciences
2021
Duy Tan University
2015-2019
Vietnam National University Ho Chi Minh City
2019
Trường ĐH Nguyễn Tất Thành
2019
Tra Vinh University
2016-2019
An in situ gel-forming system composed of rutin- and tyramine-conjugated chitosan derivatives, horseradish peroxidase (HRP), hydrogen peroxide (H2O2) was prepared applied to dermal wound repair. Rutin employed enhance production accumulation extracellular matrix the healing process. In vitro study demonstrates that released rutin significantly enhanced cell proliferation as compared with media without rutin. vivo performed by injecting hydrogels on rat dorsal wounds a diameter 8 mm for 14...
This study aimed to fabricate the potential therapeutic scaffold efficiently and safely fastening skin wound healing. A biocompatible grafting polymer-based thermal sensitive hybrid hydrogel (Chitosan-P123, CP) containing gelatin curcumin was designed be suitable stiffness for tissue regeneration. detailed in rheological found that encapsulated agents induced change of from hard soft. Especial, thermally phase transition CP governed by participant rather than curcumin. For example, at 25 wt%...
Burn wound healing is a complex multifactorial process that relies on coordinated signaling molecules to succeed. Curcumin believed be potent antioxidant and anti-inflammatory agent; therefore, it can prevent the prolonged presence of oxygen free radicals which significant factor causing inhabitation optimum process. This study describes an extension about biofunctional nanocomposite hydrogel platform was prepared by using curcumin amphiphilic chitosan-g-pluronic copolymer specialized in...
Carbon steel coupons are used to characterize inhibition efficiency and surface properties for different Ficus racemosa leaf extract (FRLE) concentrations including 0, 500, 1000, 1500 2000 ppm in an aerated 0.1 M hydrochloric acid solution. The results indicate that carbon is significantly protected by FRLE higher performances reached with increase concentration up (93.11 ± 1.99%). Additionally, the addition of reduced performance (88.86 2.15%) due high could impede formation a solid...
Kinetic modeling plays a key role in development of large-scale extraction processes. In this study, we modeled the process extracting essential oils from pomelo (Citrus maxima) peel materials different kinetics including pseudo first order and second kinetic models both linear nonlinear forms. The coefficient determination, R2, percentage deviation, %q, were used as basis to determine most suitable model kinetics. results show that non-linear (equation 7) was best fitted describe...
Background Chimeric antigen receptor (CAR) T-cell therapy target tyrosine kinase-like orphan 1 (ROR1) is broadly expressed in hematologic and solid tumors, however clinically-characterized ROR1-CAR T cells with single chain variable fragment (scFv)-R12 targeting domain failed to induce durable remissions, part due the immunosuppressive tumor microenvironment (TME). Herein, we describe development of an improved a novel, fully human scFv9 domain, augmented TGFβRIIDN armor protective against...
Fast in situ forming supramolecular hydrogels consisted of the tyramine-conjugated structures and chitosan derivative were prepared via an enzymatic reaction with horseradish peroxidase (HRP) hydrogen peroxide (H2O2). The gel formation was varied within a time period 5 s to 10 min by controlling concentrations HRP, H2O2, polymers. Tyramine conjugation at different sites structure resulted significant changes physical properties degradation that confirmed water uptake, compressive strength...
Herein, a new process to manufacture multicore micelles nanoparticles reinforced with co-assembly via hydrophobic interaction and electrostatic under the help of ultrasonication was developed. The precise between negative/hydrophobic drug positive charged amphiphilic copolymer based pluronic platform allows formation complex structures as motif predefined functions. In this study, curcumin selected model while positively on pluronic-conjugated gelatin different hydrophobicity length Pluronic...
Nanosized multi-drug delivery systems provide synergistic effects between drugs and bioactive compounds, resulting in increased overall efficiency restricted side compared to conventional single-drug chemotherapy. In this study, we develop an amphiphilic heparin-poloxamer P403 (HP403) nanogel that could effectively co-load curcuminoid (Cur) cisplatin hydrate (CisOH) (HP403@CisOH@Cur) via two loading mechanisms. The HP403 nanogels HP403@CisOH@Cur were closely analyzed with 1H-NMR...
Dendrimer, a new class of hyper-branched polymer with predetermined molecular weight, is being received much attention in nano biomedical applications such as anticancer drug delivery, gene therapy, disease diagnosis and etc. In this study, polyamidoamine (PAMAM)-based dendrimer generation 3.0 (G 3.0) was synthesized subsequently pegylated. Obtained results showed that pegylation degree the around 31% for its external amine groups. TEM image pegylated exhibited spherical shape sizes ranging...
The effect of anticancer drugs could be significantly enhanced if it is encapsulated in drug delivery vehicles such as liposomes, polymers, dendrimers and other materials. For some conventional cisplatin encapsulating methods, however, suffers from low loading efficiency. Therefore, order to overcome this limitation, our study, sonication was used preparation the nanocomplex a species aquated carboxylated PAMAM dendrimer G3.5 evaluate capacity well plantinum release behavior using FT-IR,...
In response to a mumps outbreak at the University of Iowa and surrounding community, university, state, local health officials implemented vaccination campaign targeting students <25 years age with an additional dose measles-mumps-rubella (MMR) vaccine. More than 4700 vaccine doses were administered; 97% documented third doses. We describe epidemiology before after campaign, focusing on cases in university students. Mumps identified from reportable disease databases system records. Detailed...
Nanogel-based systems loaded with single anticancer drugs display miscellaneous effectiveness in tumor remission, gradually circumventing mutation and resistance chemotherapy. Hence, the existence of dual-drug delivered nano-sized has been contemporaneous drug development preceded conventional-dose Among outstanding synergistic nanoplatforms, thermosensitive copolymer heparin-Pluronic F127 (Hep-F127) co-delivering cisplatin (CDDP) curcumins (Cur) (Hep-F127/CDDP/Cur) emerged as a notable...
Polyamidoamine (PAMAM) dendrimers are extensively researched as potential drug delivery system thanks to their desirable features such controlled and stable structures, ease of functionalization onto surface active groups. However, there have been concerns about the toxicity full generation risks premature clearance from circulation, along with other physical drawbacks presented in previous formulations, including large particle sizes low loading efficiency. In our study, carboxyl-terminated...
In recent years, injectable chitosan-based hydrogels have been widely studied towards biomedical applications because of their potential performance in drug/cell delivery and tissue regeneration. this study, we introduce a simple organic solvent-free method to prepare tyramine-tetronic-grafted chitosan (TTeC) via activation four terminal hydroxyl groups tetronic, partial tyramine conjugate into the activated product grafting remaining moiety tetronic-tyramine onto chitosan. The grafted...