A5050348327- Protein Structure and Dynamics
- RNA modifications and cancer
- Immunotherapy and Immune Responses
- Cancer Immunotherapy and Biomarkers
- Ferroptosis and cancer prognosis
- Advanced ceramic materials synthesis
- Polymer composites and self-healing
- Protein purification and stability
- Machine Learning in Bioinformatics
- Concrete and Cement Materials Research
- vaccines and immunoinformatics approaches
- Photopolymerization techniques and applications
- Food Industry and Aquatic Biology
- Smart Materials for Construction
- Plant pathogens and resistance mechanisms
- Epoxy Resin Curing Processes
- Lignin and Wood Chemistry
- Lipid metabolism and biosynthesis
- Pharmacological Effects and Toxicity Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Military Defense Systems Analysis
- Microbial Natural Products and Biosynthesis
- PI3K/AKT/mTOR signaling in cancer
- Ocular Oncology and Treatments
- Histone Deacetylase Inhibitors Research
St. John's University
2022-2025
Beijing University of Chinese Medicine
2025
Jiangxi Science and Technology Normal University
2024
Northeast Electric Power University
2024
Nanjing University of Science and Technology
2023
University of California, Santa Barbara
2022
Chengdu University of Technology
2022
Shandong University
2021
Nanchang University
2018-2021
China Building Materials Academy
2021
Breast cancer, a complex and varied disease, has four distinct subtypes based on estrogen receptor human epidermal growth factor 2 (HER2) levels, among which significant subtype known as HR+/HER2-breast cancer that spurred numerous research. The prevalence of breast cancer-related death are the most serious threats to women’s health worldwide. Current progress in treatment strategies for encompasses targeted therapy, endocrine genomic immunotherapy, supplementing traditional methods like...
Abstract Background and Objectives Actin-related protein 2/3 complex subunit 1B (ARPC1B) is an essential of the actin-related (Arp2/3) complex. While there have been numerous research reports on Arp2/3 in relation to tumors, needs be more ARPC1B its role particularly at pan-cancer level. Methods Utilizing data from cancer genome atlas (TCGA) genotype-tissue expression (GTEx) databases, we analyzed differences normal, tumor, adjacent tissues, investigating correlation with prognosis clinical...
Background/Objectives: Hyperlipidemia (HLP) encompasses a spectrum of poorly understood lipid metabolism disorders that are frequently overlooked or misdiagnosed, potentially leading to multiple complications. While the gut microbiota has been implicated in HLP pathogenesis, causal relationships and molecular mechanisms remain elusive. This study aimed investigate therapeutic Monascus-fermented ginseng (MFG) on through modulation explore treatment potential via fecal transplantation (FMT)....
Abstract Prediction of protein complex structures and interfaces potentially has wide applications can benefit the study biological mechanisms involving protein-protein interactions. However, surface prediction accuracy traditional docking methods AlphaFold-Multimer is limited. Here we present ColabDock, a framework that makes use ColabDesign, but reimplements it for purpose restrained conformation prediction. With generation-prediction architecture trained ranking model, ColabDock...
Abstract The influence of steel fiber on the mechanical properties ultra-high performance concrete (UHPC) were studied through slump, compressive strength, flexural strength test. experimental results showed that incorporation had an working UHPC, and slump expansion degree UHPC inversely proportional to volume content length-diameter ratio fiber. significantly improved UHPC. property was best when 4%, with 28 day up 163.2MPa 45.9MPa. a trend gradual decrease increase aspect condition...
Micromorphology, surface property, chemical structure and size distribution of self-healing microcapsules were characterized by ESEM, plasmon resonance analyzer, FTIR standard sieve shaker. The yield core content determinated. results showed that reaction between resorcinol UF resin shell materials could promote the polymerization particles enhance degree cross-linking materials. Particle microcapsule roughness increase with increasing degrees in resin. initially rose then decreased...
The U.S. Food and Drug Administration (FDA) first approved amivantamab, a monoclonal epidermal growth factor receptor (EGFR)-mesenchymal--epithelial transition (MET) bispecific antibody, in May 2021, to treat adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) an insertion mutation exon 20 of EGFR. approval amivantamab represents targeted therapy for this subtype NSCLC. In contrast other drugs that inhibit the tyrosine kinase activity protein, EGFR, has...