A5040109158- Employment and Welfare Studies
- Workplace Health and Well-being
- Retirement, Disability, and Employment
- Occupational Health and Safety Research
- Adolescent and Pediatric Healthcare
- Disability Education and Employment
- Pancreatic function and diabetes
- Musculoskeletal pain and rehabilitation
- Cerebral Palsy and Movement Disorders
- Spinal Cord Injury Research
- Autoimmune and Inflammatory Disorders Research
- Global Health Workforce Issues
- Complex Systems and Decision Making
- Healthcare Policy and Management
- Workplace Violence and Bullying
- Digital Economy and Work Transformation
- Regulation of Appetite and Obesity
- Policing Practices and Perceptions
- Mental Health and Patient Involvement
- Geriatric Care and Nursing Homes
- Job Satisfaction and Organizational Behavior
- Health Policy Implementation Science
- Health disparities and outcomes
- COVID-19 Pandemic Impacts
- Fibromyalgia and Chronic Fatigue Syndrome Research
Public Health Ontario
2012-2024
University of Toronto
2015-2024
Institute for Work & Health
2016-2024
Health Canada
2024
Health Solutions (Sweden)
2022
University Health Network
2022
St Michaels Hospital
2022
3M (United States)
2014-2022
Princess Margaret Cancer Centre
2022
McMaster University
2009-2021
Despite legislation on diversity in the workplace, people with disabilities still do not experience same access to work opportunities as their counterparts without disabilities. Many employers have been shown harbor sincere yet ill-founded views about work-related abilities of disabilities; these negative are often a result interrelated concerns that permeate entire employment cycle. In this paper, we provide evidence-based responses 11 specific disabilities, from pre-employment and entry...
The stresses encountered during islet isolation and culture may have deleterious effects on beta-cell physiology. However, the biological response of human cells to remains poorly characterized. A better understanding network signaling pathways induced by culturing lead strategies aimed at improving graft survival function. Laser capture microdissection (LCM) was used extract RNA from 1) intact pancreatic islets, 2) freshly isolated 3) islets cultured for 3 days, changes in gene expression...
The digital transformation of the economy is characterized by rapid advancement and wide-spread workplace application technologies. Our study aimed to unpack how contributes challenges opportunities for sustainable employment health persons living with disabilities. One-on-one semi-structured interviews policy makers, disability service providers future work specialists were conducted. Interviewees asked about implications technology advancements Participants also strategies that could be...
The adipocyte hormone leptin acts centrally and peripherally to regulate body weight glucose homeostasis. pancreatic β-cell has been shown be a key peripheral target of leptin, with suppressing insulin synthesis secretion from β-cells both in vitro vivo. Mice disrupted signaling (leprflox/flox RIPcre tg+ mice) display hyperinsulinemia, resistance, intolerance, obesity, reduced fasting blood glucose. We hypothesized that hyperinsulinemia precedes the development resistance increased adiposity...
Purpose Employers increasingly are asked to accommodate workers living with physical and mental health conditions that cause episodic disability, where periods of wellness punctuated by intermittent often unpredictable activity limitations (e.g., depression, anxiety, arthritis, colitis). Episodic disabilities may be challenging for workplaces which must comply legislation protecting the privacy information while believing they would benefit from personal details meet a worker's accommodation...
Abstract Introduction The future of work is characterized by changes that could disrupt all aspects the nature and availability work. Our study aims to understand how result in conditions, which contribute vulnerability for different groups workers. Methods A horizon scan was conducted systematically identify synthesize diverse sources evidence, including academic gray literature resources shared over social media. Evidence synthesized, trend categories were developed through iterative...
Abstract Deciding whether to disclose a disability others at work is complex. Many chronic mental and physical health conditions are associated with episodic include times of relative wellness punctuated by intermittent periods activity limitations. This research draws on the disclosure processes model examine approach avoidance non-disclosure goals their association perceived positive negative workplace outcomes. Participants were 896 employed individuals (57.7% women) living or...
Individuals with physical or mental health disabilities may be particularly vulnerable to the impact of COVID-19 on their and employment.We examined COVID-19-related concerns for health, finances, organizational support among workers no disability, a physical, both factors associated perceptions.An online, cross-sectional survey was administered sample Canadians in first wave pandemic. Questions asked about perceptions, demographics (gender, age, education), work context (e.g., sector,...
Abstract Purpose Labour market integration is a widely accepted strategy for promoting the social and economic inclusion of persons with disabilities. But what kinds jobs do disabilities obtain following their into labour market? In this study, we use novel survey workers to describe compare employment quality without in Canada. Methods We administered an online, cross-sectional heterogeneous sample Canada (n = 2,794). collected data on sixteen different conditions (e.g., temporary contract,...
Objective To examine work absenteeism, job disruptions, and perceived productivity loss factors associated with each outcome in young adults living systemic lupus erythematosus (SLE) juvenile arthritis (JA). Methods One hundred forty‐three adults, ages 18–30 years SLE (54.5%) JA (45.5%), completed an online survey of experiences. Demographic, health (e.g., fatigue, disease activity), psychosocial independence, social support), context career satisfaction, control, self‐disclosure)...
The labor market is undergoing a rapid artificial intelligence (AI) revolution. There currently limited empirical scholarship that focuses on how AI adoption affects employment opportunities and work environments in ways shape worker health, safety, well-being equity. In this article, we present an agenda to guide research examining the implications of intersection between health. To build agenda, full day meeting was organized attended by 50 participants including researchers from diverse...
Workplace stress is a complex phenomenon that may often be dynamic and evolving over time. Traditional linear modeling does not allow representation of recursive feedback loops among the implicated factors. The objective this study was to develop multidimensional system dynamics model (SDM) workplace nursing aides conduct simulations illustrate how changes in psychosocial perceptions factors might influence Eight key informants with prior experience large US home workers participated...
Monoclonal antibody (mAb) candidates from high-throughput screening or binding affinity optimization often contain mutations leading to liabilities for further development of the antibody, such as aggregation-prone regions and lack solubility. In this work, we optimized a candidate integrin α11-binding mAb developability using molecular modeling, rational design, hydrophobic interaction chromatography (HIC). A homology model parental Fv region was built, revealed patches on surface...
Abstract Many older workers want to work longer. However, we understand little about the different workplace support needs they may have and whether choose share their with others. The objective of this research was qualitatively examine disclosure-support decisions among aged 50 years older. Sixty-eight participants from diverse employment sectors a range personal experiences circumstances (e.g., health conditions, caregiving responsibilities, job experiences) participated in 1 10 focus...
A key limitation to the success of islet transplantation is cell exhaustion and death during isolation following transplantation. Endoplasmic reticulum (ER) stress has been identified as an important mechanism in development β-cell dysfunction, death, diabetes. This study investigated role ER loss human posttransplantation a diabetic athymic mouse model. Islets were isolated from organ donor pancreata using intraductal enzymatic dissociation continuous density gradient purification....
Abstract Background Precarious work is an increasingly common characteristic of industrialized labor markets that can widen health inequities, especially among disadvantaged workforce segments. Study objectives are to compare precarious employment in workers with and without disabilities, examine the modifying effect disability relationships between age, job tenure work. Methods Employed Canadians ( n = 901) disabilities were surveyed on exposure working conditions. Information age collected...
Purpose The world of work is changing and creating challenges opportunities for the employment inclusion young people with disabilities. In this article, perceptions held by adults disabilities regarding participation in future are examined. Design/methodology/approach One-on-one interviews were conducted Canadian (ages 18–36 years) living a disability. Participants asked about their thoughts impact nature on labor market involvement career aspirations. A thematic analysis was performed to...