Jonathan L. Jeger

ORCID: 0000-0003-0330-6286
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Spinal Fractures and Fixation Techniques
  • Workplace Health and Well-being
  • Nerve Injury and Rehabilitation
  • Pelvic and Acetabular Injuries
  • Health Systems, Economic Evaluations, Quality of Life
  • Ion Transport and Channel Regulation
  • Agricultural economics and policies
  • Cardiac Structural Anomalies and Repair
  • Management of metastatic bone disease
  • Pancreatic and Hepatic Oncology Research
  • Tracheal and airway disorders
  • Bone fractures and treatments
  • Endoplasmic Reticulum Stress and Disease
  • Surgical Simulation and Training
  • Cellular transport and secretion
  • Additive Manufacturing and 3D Printing Technologies
  • Mental Health Treatment and Access
  • Autophagy in Disease and Therapy
  • Spinal Dysraphism and Malformations
  • Occupational Therapy Practice and Research
  • Aortic Disease and Treatment Approaches
  • Diversity and Career in Medicine
  • Pancreatitis Pathology and Treatment
  • Clinical Reasoning and Diagnostic Skills

WinnMed
2023-2025

Mayo Clinic Hospital
2025

Mayo Clinic in Florida
2023-2025

Trinity College Dublin
2019-2021

Duke University
2016-2020

Children's Hospital of Philadelphia
2019

Artificial intelligence (AI) is a powerful computational tool that being utilized more frequently in healthcare. AI holds promise within surgical practice, including application the care of challenging patient populations. Complex spine reconstruction requires thorough multi-variable preoperative analysis and then precise enactment plan. Spino-plastics employs vascularized bone grafts (VBGs) to augment spinal fusion these high-risk patients. In this article, we discuss great breadth...

10.20517/ais.2024.73 article EN Artificial Intelligence Surgery 2025-01-04

Endoplasmic reticulum protein of 29 kDa (ERp29) is a thioredoxin-homologous endoplasmic (ER) that regulates the biogenesis cystic fibrosis transmembrane conductance regulator (CFTR) and epithelial sodium channel (ENaC). ERp29 may promote ENaC cleavage increased open probability by directing to Golgi via coat complex II (COP II) during biogenesis. We hypothesized ERp29's C-terminal KEEL ER retention motif, KDEL variant associated with less robust retention, strongly influences its regulation...

10.1074/jbc.ra119.008331 article EN cc-by Journal of Biological Chemistry 2019-10-25

QUESTIONS UNDER STUDY: In Switzerland, psychiatric evaluations of work capacity for determining a person’s eligibility disability benefits are being criticised lack transparency and high inter-rater variability. The aims this study were to learn about the current practice psychiatrists, explore possible sources variability, contrast with professional guidance. METHODS: A national online-survey among psychiatrists who performed five or more per year. Based on discussions experts literature...

10.4414/smw.2013.13890 article EN cc-by Schweizerische medizinische Wochenschrift 2013-12-13

Carbon nanomaterials are considered promising for applications in energy storage, catalysis, and electronics. This has motivated study of their potential environmental toxicity. Recently, a novel nanomaterial consisting graphene oxide wrapped around carbon nanotube (CNT) core was synthesized. The resulting soluble graphitic nanofibers were found to have superior catalytic properties, which could result use fuel cells. Before this material undergoes widespread use, its toxicity must be...

10.1002/etc.3478 article EN Environmental Toxicology and Chemistry 2016-05-06

Summary: Pseudoarthrosis is a severe complication of spinal fusion surgery with occurrence rates as high 35%–40%. Current options revision to correct pseudoarthrosis frequently carry failure and risk developing junctional kyphosis. Pedicled vascularized bone grafts (VBGs) are an innovative approach boost via improving structural integrity increasing the delivery blood donor site. This versatile technique can be performed at different levels without additional skin incisions minimal added...

10.1097/gox.0000000000005656 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2024-04-01

The number of spinal reconstruction cases is growing, as are the accompanying complications. Wound complications after can be fatal and affect up to 19% patients undergoing major spine surgery. discipline spinoplastic surgery characterized by use vascularized bone grafts reconstruct defects, which provide better results compared with nonvascularized allogenic equivalents, owing their superior blood supply. We present a 49-year-old man defect in C3-C7 region treated reconstruction. A 5 × 6 cm...

10.1097/gox.0000000000006268 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2024-11-01

Sacral reconstruction post tumor resection has historically been executed with the placement of hardware or free tissue transfer. Reconstruction using a vascularized bone graft is an alternative that avoids complications associated This article describes first documented case spinoplastic iliac crest (IC-VBG) after sacral ependymoma. 17-year-old boy history myxopapillary He presented to local emergency department complaining 6 months urinary incontinence and progressive paresthesias...

10.1097/gox.0000000000006341 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2024-11-01
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