Xiqin Liu

ORCID: 0000-0003-0332-9023
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About
Contact & Profiles
Research Areas
  • Mental Health Research Topics
  • COVID-19 and Mental Health
  • Resilience and Mental Health
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Functional Brain Connectivity Studies
  • Psychosocial Factors Impacting Youth
  • Aging and Gerontology Research
  • Traumatic Brain Injury Research
  • Grit, Self-Efficacy, and Motivation
  • Psychological Well-being and Life Satisfaction
  • Neural and Behavioral Psychology Studies
  • Family Support in Illness
  • Axon Guidance and Neuronal Signaling
  • Posttraumatic Stress Disorder Research
  • Neural dynamics and brain function
  • Psychology of Moral and Emotional Judgment
  • Neurological Disorders and Treatments
  • Mind wandering and attention
  • Digital Mental Health Interventions
  • Face Recognition and Perception
  • Stress Responses and Cortisol
  • Alzheimer's disease research and treatments
  • Deception detection and forensic psychology

Sichuan University
2024-2025

West China Hospital of Sichuan University
2024-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2024-2025

University of Electronic Science and Technology of China
2022-2024

Zhongshan Hospital of Xiamen University
2024

Abstract Uncertainty about potential future threats and the associated anxious anticipation represents a key feature of anxiety. However, neural systems that underlie subjective experience threat under uncertainty remain unclear. Combining an uncertainty-variation paradigm allows precise modulation level momentary arousal during functional magnetic resonance imaging (fMRI) with multivariate predictive modeling, we train brain model accurately predicts intensity test it across 9 samples...

10.1038/s41467-024-45433-6 article EN cc-by Nature Communications 2024-02-20

Background. Nurses play a critical role in the medical workforce during COVID-19 pandemic while facing various difficulties and challenges. Grit, social support, self-esteem are important psychosocial factors influencing job performance. However, few studies have explored relationships among these nurses. Aim. This study aimed to examine association between grit nurses’ performance explore potential chain mediation through perceived support self-esteem. Methods. A cross-sectional survey...

10.1155/2024/6388800 article EN Journal of Nursing Management 2024-02-27

The COVID-19 pandemic has caused some individuals to experience vicarious traumatization (VT), an adverse psychological reaction those who are primarily traumatized, which may negatively impact one's mental health and well-being been demonstrated vary with personal trauma history. neural mechanism of VT how past history affects current remain largely unknown. This study aimed identify neurobiological markers that track individual differences in reveal the link between childhood cumulative (CCT) VT.

10.1111/jcpp.13989 article EN Journal of Child Psychology and Psychiatry 2024-04-17

Background: Studies have shown that media exposure to critical public events can lead secondary traumatic stress (STS). Personal trauma history, self-compassion and resilience are important factors influencing STS in healthy professionals. However, whether these variables associated with social media-induced college students the underlying mechanisms remain unclear. The purpose of this study was explore complex relationship linking childhood a large sample students.

10.1080/20008066.2025.2456322 article EN cc-by-nc European journal of psychotraumatology 2025-02-03

Abstract Arousal is fundamental for affective experience and, together with valence, defines the core space. However, a precise brain model of arousal lacking, leading to continuing debates whether neural systems generalize across valence domains and are separable from those underlying autonomic arousal. Here, we combined naturalistic fMRI predictive modeling develop signature (BAAS, discovery-validation design, n = 96) demonstrate its (1) sensitivity generalizability mental processes...

10.1101/2024.07.17.604003 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-07-22

Abstract The blood-brain barrier (BBB) is a highly selective permeability that safeguards the central nervous system (CNS) from potentially harmful substances while regulating transport of essential molecules. Its dysfunction increasingly recognized as pivotal factor in pathogenesis Alzheimer’s disease (AD), contributing to accumulation amyloid-β (Aβ) plaques. We propose an AD therapeutic strategy targeting BBB low-density lipoprotein receptor-related protein 1 (LRP1). show multivalent...

10.1101/2024.05.06.592767 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2024-05-08

Loneliness has been associated with detrimental effects on mental and physical health is increasingly recognized as a critical public issue which may be further exacerbated by societal challenges such increasing urbanization, an aging society well the COVID-19 pandemic. We here review recent findings neurocognitive mechanisms brain alterations that underpin social disconnectedness, therapeutic approaches for chronic loneliness how these lines of research can integrated to improve efficacy...

10.31234/osf.io/r4f9e preprint EN 2022-01-15
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