A5013545296- Transplantation: Methods and Outcomes
- ZnO doping and properties
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Ga2O3 and related materials
- Gas Sensing Nanomaterials and Sensors
- Pneumocystis jirovecii pneumonia detection and treatment
- Silicon and Solar Cell Technologies
- Pulmonary Hypertension Research and Treatments
- Copper-based nanomaterials and applications
- Calibration and Measurement Techniques
- solar cell performance optimization
- Water Quality Monitoring and Analysis
- Mechanical Circulatory Support Devices
- Renal Transplantation Outcomes and Treatments
- Respiratory Support and Mechanisms
- Acoustic Wave Phenomena Research
- Innovations in Concrete and Construction Materials
- Respiratory viral infections research
- CCD and CMOS Imaging Sensors
- Polyomavirus and related diseases
- Electronic and Structural Properties of Oxides
- Atomic and Subatomic Physics Research
- Asthma and respiratory diseases
- BIM and Construction Integration
- Quantum Dots Synthesis And Properties
Klinikum rechts der Isar
2018-2025
Technical University of Munich
1989-2025
LMU Klinikum
2009-2024
Ludwig-Maximilians-Universität München
2007-2017
German Center for Lung Research
2014-2017
Q-Cells (Germany)
2011-2016
Institute for Magnetospheric Physics
2015
Gesundheitszentrum Bitterfeld
2011-2012
Leipzig University
1994-2010
Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde
2009
Zinc oxide (ZnO), with its excellent luminescent properties and the ease of growth nanostructures, holds promise for development photonic devices. The recent advances in ZnO nanorods are discussed. Results from both low temperature high approaches presented. techniques which presented include metal–organic chemical vapour deposition (MOCVD), phase epitaxy (VPE), pulse laser (PLD), vapour–liquid–solid (VLS), aqueous (ACG) finally electrodeposition technique as an example a selective approach....
Although advanced medical imaging technologies give detailed diagnostic information, a low-dose, fast, and inexpensive option for early detection of respiratory diseases follow-ups is still lacking. The novel method x-ray dark-field chest might fill this gap but has not yet been studied in living humans. Enabling the assessment microstructural changes lung parenchyma, technique presents more sensitive alternative to conventional x-rays, requires only fraction dose applied CT. We application...
Background: Bronchiolitis obliterans is the most important long-term sequelae of lung transplantation limiting survival. Optimized immunosuppression, including inhalation cyclosporine A (CsA), may be a promising approach to overcome this problem. Methods: In study liposomal CsA solution was characterized in vitro, doses 10 and 20 mg were inhaled with PARI eFlow® inhaler by 12 stable transplant recipients, deposition evaluated gamma scintigraphy. Results: Inhalation leads 40 ± 6% (10 mg) 33...
Abstract Background and objective Interstitial lung diseases ( ILD ) are often associated with pulmonary hypertension (PH). This study aimed to evaluate the therapeutic benefit of phosphodiesterase‐5 PDE ‐5) inhibitors in secondary . Methods Patients PH were treated sildenafil or tadalafil. Right heart catheterization was performed before after a minimum 3‐month treatment. In addition, function, 6‐min walk distance 6MWD) plasma brain natriuretic peptide BNP concentration assessed. Results...
The room-temperature optical pseudo-dielectric-functions of single-phase, single-crystalline rocksalt-structure MgxZn1−xO with Mg-content x between 0.68 and 1 were determined in the photon energy range from 0.75to9.10eV using spectroscopic ellipsometry. refractive index spectral region below fundamental absorption edge decreases increasing Mg content. reveal structures caused critical points due to electronic band-to-band transitions free exciton formation at band-gap transition. Standard...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSolution conformation of cyclo-(Gly-Pro-Ser-D-Ala-Pro). Hydrogen-bonded reverse turns in cyclic pentapeptidesL. G. Pease, C. H. Niu, and ZimmermannCite this: J. Am. Chem. Soc. 1979, 101, 1, 184–191Publication Date (Print):January 1979Publication History Published online1 May 2002Published inissue 1 January 1979https://pubs.acs.org/doi/10.1021/ja00495a031https://doi.org/10.1021/ja00495a031research-articleACS PublicationsRequest reuse...
Abstract ZnO‐based nano‐ and micro‐structures with controlled orientation, size, lateral density were grown by specially designed two‐step pulsed laser deposition direct carbothermal growth, respectively. Different substrate orientations nucleation layers allow well‐defined tuning of growth direction arrangement the wires. As a result, axial MgZnOZnO nano quantum dots homogeneous radial core‐shell well structures are demonstrated. Donor acceptor doping microwires influence considerably both...
Abstract Background Dark-field chest radiography is sensitive to the lung alveolar structure. We evaluated change of dark-field signal between inspiration and expiration. Methods From 2018 2020, patients who underwent computed tomography (CT) were prospectively enrolled, excluding those with any condition besides emphysema visible on CT. Participants imaged in both expiration a prototype system. calculated total ∑DF coefficient ϵ , assumed be proportional number alveoli density,...
Abstract Background Accurate lung volume determination is crucial for reliable dark-field imaging. We compared different approaches the of in mean coefficient calculation. Methods In this retrospective analysis data prospectively acquired between October 2018 and 2020, patients at least 18 years age who underwent chest computed tomography (CT) were screened study participation. Inclusion criteria ability to consent stand upright without help. Exclusion pregnancy, cancer, pleural effusion,...
We investigated the surface roughness and luminescence properties of MgxZn1−xO thin films (0⩽x⩽0.19). The were grown on a-plane sapphire substrates by pulsed laser deposition. root-mean-square depends oxygen partial pressure p(O2) applied during deposition takes a minimal value 0.6nm for p(O2)=1×10−3mbar. Deposition ZnO buffer layer further diminishes roughness. photoluminescence maximum peak from is due to free excitons, which are localized in potential minima at low temperatures, shows...
Lymphangioleiomyomatosis (LAM) is a rare lung disease characterised by progressive airflow obstruction. No effective medical treatment available but therapy with sirolimus has shown some promise. The aim of this observational study was to evaluate in LAM.Sirolimus (trough level 5 - 10 ng/ml) administered ten female patients (42.4 ± 11.9 years) documented progression. Serial pulmonary function tests and six-minute-walk-distance (6-MWD) assessments were performed.The mean loss FEV1 -2.30 0.52...
Background: This study compared therapeutic azole plasma trough levels (APL) of the antimycotics itraconazole (ITR), voriconazole (VOR), and posaconazole (POS) in lung transplant recipients analyzed influencing factors. In addition, intrapatient variability for each was determined. Methods: From July 2012 to 2015, 806 APL ITR, VOR, liquid (POS-Liq), tablets (POS-Tab) were measured 173 patients Munich Lung Transplantation Program. Therapeutic defined as follows: ≥700 ng/mL; 1000–5500 POS,...
Abstract Background Human Bronchial epithelial cells (hu-BEC) have been claimed to play a significant role in the pathogenesis of chronic inflammatory airway diseases like COPD. In this context IL-8 and GM-CSF shown be key cytokines. Some antibiotics which are routinely used treat lower respiratory tract infections exert additional immunomodulatory or anti-inflammatory effects. We investigated whether these effects can also detected hu-BEC. Methods Hu-BEC obtained from patients undergoing...
Posaconazole is an extended-spectrum triazole antifungal used in the treatment and prophylaxis of Aspergillus infections. It available as oral suspension (POS-Liq) delayed-release tablets (POS-Tab). The aim this longitudinal, retrospective study was to compare clinical effectiveness, toxicity pharmacokinetics POS-Liq vs POS-Tab lung transplant recipients (LTx-recipients), who were treated with both formulations subsequently. Twenty-four consecutive LTx-recipients 191 documented posaconazole...
Background Since the outbreak of COVID-19 pandemic, a number risk factors for poor outcome have been identified. Thereby, cardiovascular comorbidity has major impact on mortality. We investigated whether coronary calcification as marker artery disease (CAD) is appropriate prediction in COVID-19. Methods Hospitalized patients with (n = 109) were analyzed regarding clinical after native computed tomography (CT) imaging screening. CAC (coronary calcium score) and (need intensive care treatment...