A5085453188- Drug Solubulity and Delivery Systems
- Drug Transport and Resistance Mechanisms
- Analytical Chemistry and Chromatography
- Advanced Drug Delivery Systems
- Analytical Methods in Pharmaceuticals
- Crystallization and Solubility Studies
- Gastrointestinal motility and disorders
- Pharmaceutical studies and practices
- HIV/AIDS drug development and treatment
- Amino Acid Enzymes and Metabolism
- Antibiotics Pharmacokinetics and Efficacy
- Pharmacological Effects and Toxicity Studies
- Gastroesophageal reflux and treatments
- Neuropeptides and Animal Physiology
- Pharmacogenetics and Drug Metabolism
- Peptidase Inhibition and Analysis
- Biochemical and Molecular Research
- RNA Interference and Gene Delivery
- Protein purification and stability
- Chemical Synthesis and Analysis
- Chemical and Physical Properties in Aqueous Solutions
- Computational Drug Discovery Methods
- Adenosine and Purinergic Signaling
- Helicobacter pylori-related gastroenterology studies
- HIV Research and Treatment
University of Michigan
2015-2024
Michigan United
2012-2020
Target (United States)
2008-2011
Center for Drug Evaluation and Research
2003-2010
Setsunan University
2006-2010
Ben-Gurion University of the Negev
2010
Yale University
2010
Therapeutics Systems Research Laboratories (United States)
1994-2008
Michigan Center for Translational Pathology
2008
Universitat de València
2003-2006
The purpose of this study is to provisionally classify, based on the Biopharmaceutics Classification System (BCS), drugs in immediate-release dosage forms that appear World Health Organization (WHO) Essential Drug List. classification report aqueous solubility reported commonly available reference literature and a correlation human intestinal membrane permeability for set 29 with their calculated partition coefficients. WHO List consists total 325 medicines 260 drugs, which 123 are oral (IR)...
Orally administered, immediate-release (IR) drug products in the top 200 product lists from United States (US), Great Britain (GB), Spain (ES), and Japan (JP) were provisionally classified based on Biopharmaceutics Classification System (BCS). The provisional classification is aqueous solubility of drugs reported readily available reference literature a correlation human intestinal membrane permeability for set 29 with their calculated partition coefficients. Oral IR constituted more that...
The rate and extent of drug dissolution absorption from solid oral dosage forms is highly dependent upon the volumes distribution gastric small intestinal water. However, little known about time courses water in vivo an undisturbed gut. Previous imaging studies offered a snapshot fasted humans showed that intestine distributed pockets. This study aimed to quantify volume number pockets upper gut healthy following ingestion glass (240 mL, as recommended for bioavailability/bioequivalence...