A5060688761- Head and Neck Surgical Oncology
- Healthcare Systems and Public Health
- Bone health and osteoporosis research
- Boron Compounds in Chemistry
- Ultrasound and Hyperthermia Applications
- Glioma Diagnosis and Treatment
- Head and Neck Cancer Studies
- Facial Trauma and Fracture Management
- Bone Tissue Engineering Materials
- Nanoplatforms for cancer theranostics
- Ear and Head Tumors
- Medical History and Innovations
- Biomarkers in Disease Mechanisms
- Facial Nerve Paralysis Treatment and Research
- Medical and Biological Sciences
- Salivary Gland Tumors Diagnosis and Treatment
- Photoacoustic and Ultrasonic Imaging
- Immunodeficiency and Autoimmune Disorders
- Dental Implant Techniques and Outcomes
- Medical Imaging Techniques and Applications
- Cancer Genomics and Diagnostics
- Brain Metastases and Treatment
- Vitamin D Research Studies
- Ferroptosis and cancer prognosis
- Ultrasound in Clinical Applications
Tomsk National Research Medical Center
2017-2025
Russian Academy of Sciences
2017-2025
Siberian State Medical University
2020-2025
Federal Medical-Biological Agency
2023
National Research Tomsk State University
2018-2022
National Research Center for Preventive Medicine
2019-2020
Ministry of Health of the Russian Federation
2015-2020
Tomsk Cancer Research Institute
2016-2019
Saint Petersburg State Pediatric Medical University
2018
City Hospital № 1 named after. ON. Semashko
2017
Several studies have shown that the increased expression of delta–like noncanonical Notch ligand 1 (DLK-1) is associated with more aggressive tumor characteristics in patients glioblastoma. The aim study was to estimate diagnostic and prognostic values DLK-1 serum levels glioblastoma patients. Material Methods . included 39 newly diagnosed level evaluated paired cerebrospinal fluid samples before starting chemoradiotherapy (CRT). All received combined modality treatment. blood additionally...
Repairs of orbital post-traumatic and extensive malignant defects remain a major surgical challenge, in view follow-up outcomes. Incorrect management injured facial structures results cosmetic, ophthalmic, social aftereffects. A custom-made knitted TiNi-based mesh (KTNM) endograft was employed to overcome post-surgical complications post-resected lesions the area. Preoperative high-resolution computed tomography (CT) imaging CAD modelling were used design customized KTNM each case....
In this study, thin calcium phosphate (Ca-P) coatings were deposited on zirconia substrates by radiofrequency (RF) magnetron sputtering using different targets (calcium tribasic (CPT), hydroxyapatite (HA), monobasic, dibasic dehydrate (DCPD) and pyrophosphate (CPP) powders). The of monobasic DCPD powders was carried out without an inert gas in the self-sustaining plasma mode. physico-chemical, mechanical biological properties investigated. Cell adhesion examined mesenchymal stem cells...
The purpose of the study was to evaluate efficacy neutron therapy (NT) for salivary gland cancer and recurrent breast cancer. Material Methods. included 130 patients with 125 Fast using U-120 cyclotron given group. Patients control group received standard radiotherapy (external beam radiotherapy). Results. Among cancer, a recurrence rate significantly lower in who postoperative course NT compared (21.1 vs 45 %, p<0.05). five-year overall survival rates were 73.8 ± 9.5 % 43.2 9.4 group,...
The purpose of this study was to analyze the results combined modality treatment and radiation therapy using 6.3 MeV fast neutrons for salivary gland cancer prognostically unfavorable thyroid cancer. group comprised 127 patients with 46 cancer, who received neutron alone in combination surgery. obtained demonstrated that including led encouraging local control cancers.
Цель исследования. Изучить влияние эндопротезирования с применением имплантатов из никелида титана на течение процессов заживления раневой поверхности после удаления опухолей полости носа и околоносовых пазух возможность управления последними. Материалы методы. В исследование вошли 60 пациентов, получавших комбинированное лечение по поводу злокачественных придаточных Т3-4N0-1M0 в НИИ онкологии г. Томска 2002 2021 гг. включительно. Все пациенты были подразделены 3 группы соответствии видом...
Научно-практическая ревматология.2019;57(6):626-635 О р и г н а л ь ы е с д о в я 1 ФГБОУ ВО «Северо-Западный государственный медицинский университет им.И.И.Мечникова» Минздрава России, Санкт-Петербург, Россия; 2 СПб ГБУЗ «Клиническая ревматологическая больница №25», 3 «Ярославский университет» Ярославль, 4 ФГБУ «Национальный центр профилактической медицины» Москва, 5 ООО «Макс К» Медицинский «Максимум здоровья», Томск, 6 «Сибирский 7 ФГБНУ «Научно-исследовательский институт клинической...
High-grade malignant gliomas (WHO grade G III–IV) account for more than 50% of all primary brain tumors. Despite aggressive treatment, survival rates are still very low with a median reported no 1.5 years.Radiation therapy is an integral part the combined but often does not influence lethally on resistant tumor cells. Thereby, in recent decades there has been active search novel approaches to treatment (chemotherapeutic drugs, biological modifiers, local hyperthermia). Experimental data...
To estimate the informative value of ultrasonography (USG) in diagnosis lung injuries pregnant women with blood system tumors.Lung ultrasound was performed 5 patients cancers. The women's age 29-38 years; gestational 14-33 weeks. Four had different types acute leukemia; one primary mediastinal large B-cell lymphoma. All received chemotherapy for cancer. When there were signs injury, USG conducted, results which necessitated therapy or bronchoalveolar lavage (BAL).Three developed respiratory...
Despite the achievements in current strategies for treatment, prognosis malignant glioma patients remains unsatisfactory. Hyperthermia is currently considered to be most effective and universal modifier of radiotherapy chemotherapy. Preliminary treatment outcomes 28 with newly diagnosed (23) recurrent (5) high-grade gliomas were presented. All received multimodality including surgery, thermoche-moradiotherapy followed by 4 cycles adjuvant endured thermochemoradiotherapy well. A complication,...
Background : The identification of genetic factors that are simultaneously responsible for the predisposition to development cardiovascular diseases (CVD) and osteoporosis (OP) is important prevention both conditions. Aim aim this study evaluate three risk scales (GRS) previously showed an association with bone mineral density (BMD) fracture risk, as well associations these GRS vascular wall pathology. Materials methods 250 female outpatients (aged 45 69) were enrolled into a cross-sectional...
The paper presents the results of a multicenter postmarketing clinical laboratory study Eplan ointment and eplan solution for topical treatment skin soft tissue infections in outpatient, inpatient, field settings. 793 patients with different locations genesis demonstrate high efficacy medicaments along their easy-to-use formulation economic availability.
Purpose: to summarize available data on the diagnostic value of various circulating biomarkers for detection glioblastoma recurrence. Material and Methods. A literature search was conducted using PubMED ExoCarta SILVA databases. Results. Glioblastoma multiforme (GBM) is most common glioma in adults with an unfavorable prognosis. Treatment tumor recurrence can improve survival patients. Neuroimaging standard method diagnosing brain However, a neuroimaging clearly distinguish between pseudo...
Aim . To study associations between arterial stiffness and bone mineral density in postmenopausal women. Material methods The intima-media thickness (IMT), the presence number of atherosclerotic plaques (AP) were studied using duplex scanning. Pulse wave velocity (PWV), augmentation index (AI) measured by applanation. Bone (BMD) spine, hip neck (HN) proximal (PH) was double energy x-ray absorptiometry. Results A significant correlation PWV with age, duration menopause revealed, a more...
The purpose of the study was to evaluate effectiveness treatment patients with recurrent nasal cavity and paranasal sinus cancer using photodynamic diagnosis (PDD) therapy (FDT). Material Methods . included 40 locally advanced cancer, who were admitted clinics Cancer Research Institute Tomsk National Medical Center disease progression or recurrence. All divided into group (n=20) control (n=20). Patients in both groups received chemotherapy combined radiotherapy, surgery a combination...
A new technique of concurrent chemoradiotherapy and local electromagnetic hyperthermia for treatment patients with newly diagnosed glioblastoma was developed at the Cancer Research Institute Tomsk National Medical Center. total 20 received temozolamide hyperthermia. Local performed using Celsius TCS device, 2 times a week (8–10 sessions). All tolerated well. The most common toxicity profile thermochemoradiotherapy hematological neurological. It should be noted that no neurological found in...
The purpose of this study was to analyze the results combined modality treatment and radiation therapy using 6.3 MeV fast neutrons c. included 45 patients with thyroid gland cancers who received alone use generated within U-120 cyclotron. clinical trial neutron-photon used in combination surgery for aggressive forms cancer showed feasibility increasing effectiveness due reduction incidence local recurrences. In addition, satisfactory tolerance absence severe specific complications dictate...
Surgical treatment is leading in the of malignant tumors salivary glands. The complexity anatomical areas, severity tumor process, close location facial nerve branches lead to frequent complications postoperative period. technique elimination paresis mimic muscles with use a complex therapeutic measures, including course physiotherapy appointment magnetolaser and SCENAR therapy developed at Cancer Research Institute, Tomsk National Medical Center RAS prospect its this pathology. clinical...