- Geriatric Care and Nursing Homes
- Diet and metabolism studies
- COVID-19 and healthcare impacts
- Palliative Care and End-of-Life Issues
- Product Development and Customization
- Quality and Supply Management
- Intensive Care Unit Cognitive Disorders
- Manufacturing Process and Optimization
- Regulation of Appetite and Obesity
- Frailty in Older Adults
- Quality and Management Systems
- Fuel Cells and Related Materials
- Design Education and Practice
- Operations Management Techniques
- Tryptophan and brain disorders
- Innovation and Knowledge Management
- Ergonomics and Human Factors
- Dementia and Cognitive Impairment Research
- Long-Term Effects of COVID-19
- Cardiac Ischemia and Reperfusion
- Alzheimer's disease research and treatments
- Lipid Membrane Structure and Behavior
- Flexible and Reconfigurable Manufacturing Systems
- Trauma and Emergency Care Studies
- Ergonomics and Musculoskeletal Disorders
McMaster University
2025
Virginia Commonwealth University
2020-2024
Eastern Virginia Medical School
2016-2018
Walter Reed National Military Medical Center
2017
University of Skövde
2013-2015
National Institutes of Health
2010-2012
National Institute on Alcohol Abuse and Alcoholism
2008-2010
United States Department of Health and Human Services
2010
Akita Industrial Technology Center
2010
Johns Hopkins University
1987
Three groups of male Wistar rats were pair fed NIH-31 diets for 14 days to which added 30% calories as corn starch, palm oil, or R-3-hydroxybutyrate-R-1,3-butanediol monoester (3HB-BD ester). On the 14th day, animal brains removed by freeze-blowing, and brain metabolites measured. Animals ketone ester diet had elevated mean blood bodies 3.5 mm lowered plasma glucose, insulin, leptin. Despite decreased leptin, feeding ad lib voluntary food intake 2-fold 6 while malonyl-CoA was increased about...
The apparent equilibrium constants, K′, of biochemical reactions containing substrates which bind [Mg2+] unequally can be significantly altered by changes in free intracellular [Mg2+]. Intracellular estimated measurements [citrate]/[isocitrate], a ratio known to vary with tissue combined constant for glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase, and triose phosphate isomerase the three (KGG-TPI′) was corrected using new binding constants dihydroxyacetone-phosphate...
Abstract Background Psychiatric comorbidity is the rule rather than exception in adult Attention-deficit Hyperactivity Disorder (ADHD) subjects, with commonest being anxiety disorders [1]. Anxiety has been shown to be associated greater symptom severity, treatment resistance, and functional impairment ADHD [2]. Stimulant medications have proven effective improving symptoms of ADHD, however, data comes from subjects without comorbidity. This trial evaluated benefit stimulant medication Aims...
Objective: To explore the perceptions of nursing home (NH) clinicians regarding factors underpinning known increases in psychotropic prescribing over COVID-19 pandemic. Methods: Three iterative online surveys were fielded to Virginia NH (11/2021–6/2022) assess their perspectives driving pandemic use. Existing literature and emerging survey data informed content. Sampling was for convenience achieved through crowdsourcing, leveraging collaborations with clinician professional organizations....
Cerebral amyloid angiopathy (CAA) can cause intracranial hemorrhage and is strongly associated with cognitive decline. Rarely, an inflammatory subtype distinctive MRI findings may recurrent but reversible microbleeds. We present a case of presumed CAA-related inflammation. An 82-year-old Caucasian female medical history significant for memory problems fourteen years, diabetes mellitus, heart failure atrial fibrillation was evaluated at skilled nursing facility following right frontal lobe...
The function of vitamin E (vitE) is typically ascribed to protection from oxidation, however recent reports describe its non‐antioxidant functions. To investigate the effects vitE in GPCR signaling, we reconstituted bovine rhodopsin into 1‐stearoyl‐2‐docosohexanoyl‐phosphatidyl choline (SDPC) bilayers. 5 and 10mol% on were determined spectroscopically by measuring equilibrium amount signaling‐competent conformation (MetaII) following photoactivation. kinetics MetaII formation was measured...
Workstation design processes are seldom as rigorous product processes. Instead, workstations often “just built”. This commonly results in that suffer from problems related to ergonomics, flexibility, logistics, productivity etc., turn leading reductions human wellbeing and/or economics. The problem is a lack of information, about ergonomics or other relevant areas, itself. rather knowledge how find, interpret and use the information proactively workstations, e.g. definition complete set...