A5057918688- Peripheral Neuropathies and Disorders
- Hereditary Neurological Disorders
- Long-Term Effects of COVID-19
- Amyotrophic Lateral Sclerosis Research
- Migraine and Headache Studies
- Retinal and Optic Conditions
- Neurological diseases and metabolism
- Pharmacological Effects and Toxicity Studies
- Pain Mechanisms and Treatments
- Peripheral Nerve Disorders
- Muscle Physiology and Disorders
- Inflammatory Myopathies and Dermatomyositis
- Bacterial Infections and Vaccines
- Neurogenetic and Muscular Disorders Research
- Glycogen Storage Diseases and Myoclonus
- Nerve Injury and Rehabilitation
- Cancer Treatment and Pharmacology
- Mycobacterium research and diagnosis
- Autoimmune Neurological Disorders and Treatments
- Dermatological and COVID-19 studies
- Spine and Intervertebral Disc Pathology
- COVID-19 Clinical Research Studies
- Lysosomal Storage Disorders Research
- Genetic Neurodegenerative Diseases
- Myasthenia Gravis and Thymoma
Isfahan University of Medical Sciences
2016-2025
Aster
2024
University of Isfahan
2018-2022
Birjand University of Medical Sciences
2020
Alzahra Medical and Education Center
2012-2020
Aix-Marseille Université
2020
Centre National de la Recherche Scientifique
2020
Centre de Résonance Magnétique Biologique et Médicale
2020
Nenagh Hospital
2007
University Hospital Limerick
2007
Abstract The extracellular matrix comprises a network of macromolecules such as collagens, proteoglycans and glycoproteins. VWA1 (von Willebrand factor A domain containing 1) encodes component the that interacts with perlecan/collagen VI, appears to be involved in stabilizing structures, demonstrates high expression levels tibial nerve. Vwa1-deficient mice manifest abnormal peripheral nerve structure/function; however, variants have not previously been associated human disease. By...
Guillain-Barre Syndrome (GBS) is an autoimmune acute inflammatory demyelinating polyneuropathy usually elicited by upper respiratory tract infection. Several studies reported GBS associated with Coronavirus Disease 2019 (COVID-19) In this study, we described nine patients following the COVID-19 vaccine.
Abstract Background Fat infiltration in individual muscles of sporadic inclusion body myositis (sIBM) patients has rarely been assessed. Methods Sixteen sIBM were assessed using MRI the thighs and lower legs (LL). The severity fat infiltration, proximal‐to‐distal side asymmetries, correlations with clinical functional parameters investigated. Results All had fat‐infiltrated muscles, more severely affected than LL. A gradient was mainly observed for adductors, quadriceps, sartorius, medial...
The global COVID-19 pandemic was initiated by the appearance of novel coronavirus SARS-CoV-2 in 2019, presenting a spectrum clinical manifestations from asymptomatic cases to severe pneumonia and multi-organ dysfunction, with some leading death induced hyperinflammatory responses. Neurological have been reported more than one-third patients, particularly instances. While vaccines are pivotal combating infectious diseases enhancing public health, reports linked Guillain–Barré syndrome (GBS)...
Background Guillain-Barré syndrome (GBS) is an inflammatory disorder causing severe disability and death. The sympathetic skin response (SSR) RR interval variability are non-invasive tests that measure autonomic dysfunction. aim of this study was to investigate the relationship SSR variation with prognosis in patients GBS Isfahan, Iran.
Background: Amyotrophic lateral sclerosis (ALS) is a life-threatening progressive motor neuron disease whose diagnosis challenging because of lacking specific diagnostic means. The current study aims to assess the value upper extremity peripheral nerves ultrasonography in ALS detection. Materials and Methods: In this case-control study, 30 subjects were assessed regarding cross-sectional area (CSA) proximal (at distal part arm or elbow) wrist level) median ulnar nerves, via ultrasonography....
A simple method is described for measuring the area of anterior fontanelle at birth. Normal values in preterm and term infants suggest enlargement with gestational age. Small-for-dates have significantly larger fontanelles than either or infants. Knowledge normal variation size may be help early diagnosis congenital hypothyroidism provide a clue to other disorders skeletal development.
The autoimmune disease myasthenia gravis (MG), can mimic a variety of neurological disorders leading to delay in diagnosis and treatment. On occasions, misdiagnosis MG could lead unnecessary therapeutic interventions. We report the case 50 year-old man, whom was mistaken for motor neuron (MND). Subsequently, correct optimal management resulted saving his life significant improvement functional status. discuss importance considering as one potential differential diagnoses among cases new...
Childhood gastroenteritis remains a common reason for admission to British paediatric units, although the severity of disease appears be diminishing in recent years. We studied 215 infants and children with admitted consecutively four units South Wales order determine disease, organisms isolated, frequency complications, adequacy management before admission. Stool pathogens were isolated 125 (58%) patients (viruses 65, bacteria 30, protozoa 19, multiple infection found 11). There was low...
Guillain-Barre syndrome (GBS) is an immune-mediated peripheral neuropathy. We compared clinical, laboratory characteristics, and disease course of GBS subtypes in a large group Iranian patients Isfahan.We collected data from who were admitted to Alzahra referral university Hospital, Isfahan, Iran with diagnosis GBS. In this population-based cross-sectional research, characteristic 388 cases between 2010 2015 studied.The current study recruited including 241 males (62.1%) 147 females (37.9%)...
Abstract Background Motor neuron disorders involving upper and lower neurons are a genetically clinically heterogenous group of rare neuromuscular with overlap among spinal muscular atrophies (SMAs) amyotrophic lateral sclerosis (ALS). Classical SMA caused by recessive mutations in SMN1 is one the most common genetic causes mortality infants. It characterized degeneration anterior horn cells cord, leading to progressive muscle weakness atrophy. Non‐SMN1‐related variants number genes,...
Summary Two cases of refractory acute myeloid leukaemia were treated with methoxy-9-ellipticine lactate alone and in combination other chemotherapeutic agents. In the first patient a successful complete second third remission was achieved lasting 2 3 months respectively. However, partial obtained as treatment only started terminal phase illness. view resistance this form to present drugs both initally at time relapse, response these two is worth reporting.
Rubella neutralization and haemagglutinin-inhibition tests were used to determine the incidence of rubella antibodies in sera 235 children adolescents aged 1 month 20 years. The showed good agreement detection resulting from acute infection. Maternal became undetectable within six months after birth. proportion possessing was found be about 23% by age 5 years, rising sharply 80% 6–12 years group 83% 13–20 group. Results indicate that infection may higher females than males. correlation...
Background: The role of endothelial progenitor cells (EPCs) in the maintenance vascularization following ischemic brain after experimental stroke has been established. Accordingly, this study, we evaluated circulating EPCs transient attack (TIA) patients for future cerebrovascular (CV) events. Materials and Methods: level (staining markers: CD34, CD309) were determined using flow cytometry at 24 h TIA thirty consecutive patients. was also once healthy volunteers. Over a period 12 months, all...
Summary In a retrospective study, comparison was made of clinical and laboratory data in 14 patients with meningococcaemia 40 meningococcal meningitis. Significant differences were found duration symptoms, onset purpura, presence shock, initial WBC, ESR, serum fibrin degradation products. The overall mortality rate this series 7%, 4 dying, but none This study indicates the importance pathological grading meningococcaemia. Death occurred only presenting 3 or more adverse factors detailed.
S ummary . The presenting features and clinical course of 89 adults 15 children with acute myeloblastic leukaemia (AML) to a Regional Leukaemia Centre has been analysed. Remission rate was related age, being 40% for the total adult group 60% all children. Young had particularly high remission rate, whilst elderly patients faired badly. Survival diminished increasing age who entered complete survived significantly longer time ( P <0.001) than those did not. Adult AML differs from childhood...