A5100400246- Electrochemical sensors and biosensors
- Extracellular vesicles in disease
- Advancements in Battery Materials
- Bioinformatics and Genomic Networks
- Advanced Battery Technologies Research
- Advanced Sensor and Energy Harvesting Materials
- Advanced Nanomaterials in Catalysis
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Advanced biosensing and bioanalysis techniques
- MicroRNA in disease regulation
- Advanced Battery Materials and Technologies
- Catalytic Processes in Materials Science
- Neural Networks and Applications
- RNA regulation and disease
- Gas Sensing Nanomaterials and Sensors
- Advanced Chemical Sensor Technologies
- Advanced MRI Techniques and Applications
- CRISPR and Genetic Engineering
- Gut microbiota and health
- Perovskite Materials and Applications
- Functional Brain Connectivity Studies
- Nanoplatforms for cancer theranostics
- Electrochemical Analysis and Applications
- Nanopore and Nanochannel Transport Studies
Chongqing University
2018-2025
Shenzhen University
2013-2025
Shenzhen Children's Hospital
2025
Nanchang University
2025
Massachusetts Institute of Technology
2024-2025
Wuhan University of Science and Technology
2023-2024
Guizhou University
2024
Northwest A&F University
2017-2024
Nanjing Forestry University
2023-2024
BGI Group (China)
2024
The development of enzyme-like electrochemical sensors with atomic-level catalytic activity sites is essential for the accurate and sensitive detection active molecules in biological fluids. In this study, a signal amplification platform simultaneous analysis dopamine (DA) uric acid (UA) was prepared on screen-printed carbon electrode (SPCE). sensing combines polypyrrole (Ppy) high electrical conductivity cobalt single-atom nanozymes tubular bis-paraben nitrogen-carbon (Co-NNC) excellent...
The developmental competence of in vitro cultured (IVC) embryos is markedly lower than that their vivo counterparts, suggesting the need for optimization IVC protocols. Embryo culture medium routinely replaced three days after initial bovine, however, whether this protocol superior to continuous nonrenewal method under current conditions remains unclear. Using bovine somatic cell nuclear transfer (SCNT) as model, our results showed compared with routine renewal treatment, system...
The exponential growth of high-throughput DNA sequence data has posed great challenges to genomic storage, retrieval and transmission. Compression is a critical tool address these challenges, where many methods have been developed reduce the storage size genomes sequencing (reads, quality scores metadata). However, are being generated faster than they could be meaningfully analyzed, leaving large scope for developing novel compression algorithms that directly facilitate analysis beyond...
Resting sweat analysis could provide unique insight into the metabolic levels of physiological and pathological states. However, low secretion rate resting concentration molecules pose challenges for development noninvasive wearable sensors. Here, we demonstrated a patch precise uric acid at rest. Fe single-atom nanozymes (FeSAs) with excellent electrocatalytic activity were used to develop sensor selective catalysis (UA, 1-425 μM), catalytic mechanism UA was later explored by density...
Exosomes are important participants in numerous pathophysiological processes and hold promising application value cancer diagnosis, monitoring, prognosis. However, the small size (40–160 nm) high heterogeneity of exosomes make it still challenging to enrich efficiently from complex biological fluid microenvironment, which has largely restricted their downstream analysis clinical application. In this work, we introduced a novel method for rapid isolation mild release cell culture supernatant....
Abstract Domestic pigs (Sus scrofa) are the leading terrestrial animals used for meat production. The gut microbiota significantly affect host nutrition, metabolism, and immunity. Hence, characterization of microbial structure function will improve our understanding resources mechanisms underlying host–microbe interactions. Here, we investigated microbiomes seven pig breeds using metagenomics 16S rRNA gene amplicon sequencing. We established an expanded reference catalog comprising 17 020...
Vehicle-mounted ground-penetrating radar (GPR) has been used to non-destructively inspect and evaluate railway subgrade conditions. However, existing GPR data processing interpretation methods mostly rely on time-consuming manual interpretation, limited studies have applied machine learning methods. are complex, high-dimensional, redundant, in particular with non-negligible noises, for which traditional not effective when interpretation. To solve this problem, deep is more suitable process...
Extracellular vesicles (EVs) are available in various biological fluids and have highly heterogeneous sizes, origins, contents, functions. Rapid enrichment of high-purity EVs remains crucial for enhancing research on tumors. In this work, we present a magnetic nanoparticle-based microfluidic platform (ExoCPR) on-chip isolation, purification, mild recovery from cell culture supernatant plasma within 29 min. The ExoCPR chip integrates bubble-driven micromixers immiscible filtration assisted by...
Safety issues are one of the main limitations for further application lithium-ion batteries, and battery degradation is an important causative factor. However, current state-of-health (SOH) estimation methods mostly developed a single feature operating condition as well material system, which consequently makes it difficult to guarantee robustness generalization. This paper proposes data-driven multi-feature collaborative SOH method based on equal voltage interval discharge time, incremental...
This study develops an end-cloud collaboration method for estimating the State-of-Health (SOH) of batteries. It fuses a cloud-based deep learning model detailed analysis and end-side swift evaluation, employing Bidirectional Long Short Term Memory networks attention mechanism precise feature identification. A comprehensive extraction methodology, incorporating incremental capacity differential thermal analyses, ensures robust correlation with battery degradation. The Extended Kalman Filter...
Developing an accurate, reliable, and stable glucose detection sensor poses a formidable challenge for the food industry. In this study, hydrothermal wet chemical methods were employed to fabricate Pt single-atom catalyst on Co3O4 (Co3O4/Pt SAs), where dispersed atoms collaboratively catalyze electrochemical reaction electrode surface. Subsequently, integration of microelectrode with polyethylene glycol diacrylate (PEG-DA) hydrogel dual-channel microfluidic chip facilitated continuous rapid...
High intensity focused ultrasound (HIFU) is a noninvasive thermal ablation technique for the treatment of benign and malignant solid masses. To improve efficacy HIFU ablation, we developed poly (lactide-co-glycolide) (PLGA) nanoparticles encapsulating perfluoropentane (PFP) hematoporphyrin monomethyl ether (HMME) as synergistic agents (HMME+PFP/PLGA). Two-step biotin-avidin pre-targeting was applied ablation. We further modified with streptavidin (HMME+PFP/PLGA-SA). HMME+PFP/PLGA-SA were...
Excessive accumulation of hydrogen peroxide (H2O2) in the physiological pool can cause oxidative stress cells and eventually lead to occurrence diseases. Therefore, accurate real-time detection H2O2 is great significance for disease prevention. In this study, an Fe single-atom nanozyme (Fe-SNC) with Fe-N4 active center was synthesized, which showed excellent peroxidase-like activity acidic environment amazing electrocatalytic reduction reaction. Based on this, we proposed a colorimetric...