About
Contact & Profiles
A5041006952
Research Areas
- Circadian rhythm and melatonin
- Neuroendocrine regulation and behavior
- Nitric Oxide and Endothelin Effects
University of Birmingham
2007
Nitric oxide (NO) enhances human sperm motility and capacitation associated with increased protein phosphorylation. NO activates soluble guanylyl cyclase, but can also modify function covalently via S-nitrosylation of cysteine. Remarkably, this mechanism remains unexplored in although they depend on post-translational modification to achieve changes required for fertilisation. Our objective was identify targets sperm. Spermatozoa were incubated donors S-nitrosylated proteins identified using...
10.1002/pmic.200700254
article
EN
PROTEOMICS
2007-08-07
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