A5054969766- Hepatitis B Virus Studies
- Circular RNAs in diseases
- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Hepatitis C virus research
- Immunotherapy and Immune Responses
Third Affiliated Hospital of Sun Yat-sen University
2021-2022
Sun Yat-sen University
2021-2022
Acute-on-chronic liver failure (ACLF) is a severe syndrome associated with high mortality. Alterations in the microenvironment are one of vital causes immune damage and dysfunction. Human bone marrow mesenchymal stem cells (hBMSCs) have been reported to alleviate injury via exosome-mediated signaling; note, miRNAs most important cargoes exosomes. Importantly, within exosomes hepatic may mediate cell (MSC)-derived regulation function. This study investigated hepatocyte exosomal which...
It is unclear whether hepatitis B surface antibody (HBsAb) confers clinical benefits after HBsAg seroclearance, especially in antigen (HBsAg) seroreversion and maintenance of HBsAb. We evaluated this patients (n = 222) with loss following treatment pegylated interferon (PEG-IFN)-based therapy who completed a 48-week follow-up period. Serum virus (HBV) markers biochemical indicators were every 3 months. The primary endpoint was seroreversion. Factors associated also investigated. HBsAb ≥100...