Xuewen Fang

ORCID: 0000-0003-0404-752X
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Advanced X-ray and CT Imaging
  • Thyroid Cancer Diagnosis and Treatment
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Asthma and respiratory diseases
  • Smoking Behavior and Cessation
  • S100 Proteins and Annexins
  • Radiation Dose and Imaging
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Welding Techniques and Residual Stresses
  • Brain Metastases and Treatment
  • Nematode management and characterization studies
  • Alzheimer's disease research and treatments
  • Plant-Microbe Interactions and Immunity
  • Lung Cancer Diagnosis and Treatment
  • Glioma Diagnosis and Treatment
  • Dendrimers and Hyperbranched Polymers
  • Older Adults Driving Studies
  • Nanoparticle-Based Drug Delivery
  • Cardiac Health and Mental Health
  • Intracranial Aneurysms: Treatment and Complications
  • Legume Nitrogen Fixing Symbiosis
  • Stroke Rehabilitation and Recovery
  • Neurological Disease Mechanisms and Treatments

Dongguan People’s Hospital
2014-2024

Southern Medical University
2020-2024

First People's Hospital of Yunnan Province
2023

China Agricultural University
2019

Bacillus subtilis GLB191 (hereafter GLB191) is an efficient biological control agent against the biotrophic oomycete Plasmopara viticola, causal of grapevine downy mildew. In this study, we show that supernatant also highly active mildew and activity results from both direct effect pathogen stimulation plant defences (induction defence gene expression callose production). High-performance thin-layer chromatography analysis revealed presence cyclic lipopeptides fengycin surfactin in...

10.1111/mpp.12809 article EN cc-by Molecular Plant Pathology 2019-05-18

Background: Anxiety is prevalent after a stroke. The pathophysiological mechanisms underlying the development of poststroke anxiety (PSA) remain unclear. aim this study was to investigate clinical and neuroimaging risk factors for PSA examine effects on activities daily living (ADL) quality life (QOL) in Chinese patients with ischemic Methods: Two hundred nineteen acute stroke were recruited study. A series comprehensive assessments, including Hamilton Rating Scale (HARS), Depression (HDRS),...

10.3389/fpsyt.2019.00257 article EN cc-by Frontiers in Psychiatry 2019-04-17

Abstract Introduction Very few studies have investigated the specific relationship between neutrophil‐to‐lymphocyte ratio (NLR) and short‐term outcomes of patients suffering from mild acute ischemic stroke (AIS) receiving intravenous thrombolysis (IVT). This study aimed to investigate whether a high NLR is associated with poor outcome in AIS after IVT. Methods We retrospectively analyzed data that were prospectively acquired treated Mild was defined as National Institutes Health Stroke Scale...

10.1002/brb3.1857 article EN cc-by Brain and Behavior 2020-09-27

Susceptibility weighted imaging (SWI) provides an approximate assessment of tissue perfusion and shows prominent hypointense cortical veins in the ischemic territory because increased concentration deoxyhemoglobin. We aimed to evaluate whether asymmetrical vein sign (APCVS) on SWI can predict early neurological deterioration (END) acute stroke patients with severe intracranial arterial stenosis or occlusion (SIASO).One hundred nine SIASO who underwent were retrospectively recruited. END was...

10.1186/s12883-020-01907-w article EN cc-by BMC Neurology 2020-09-02

Abstract Introduction To assess whether the asymmetrical cortical vessel sign (ACVS) on susceptibility‐weighted imaging (SWI) could predict 90‐day poor outcomes in anterior circulation acute ischemic stroke (AIS) patients treated with recombinant tissue plasminogen activator (r‐tPA). Methods Clinical data of consecutive AIS r‐tPA were retrospectively analyzed. variables included age, sex, vascular risk factors, NIHSS score, onset to treatment time, and initial hematologic neuroimaging...

10.1002/brb3.1657 article EN cc-by Brain and Behavior 2020-05-20

Intracranial atherosclerotic stenosis (ICAS) is the leading cause of ischemic stroke worldwide. Hyperlipidemia a major contributor to atherosclerosis. However, effect hyperlipidemia on evolution intracranial plaques and downstream episodes remains unclear. In this study, we aimed assess radiological features ICAS explore relationship between plaque progression.We included people with (≥50% stenosis) undergoing high-resolution magnetic resonance imaging. The culprit was defined as sole, or in...

10.5551/jat.63971 article EN Journal of Atherosclerosis and Thrombosis 2023-01-27

Nasopharyngeal carcinoma (NPC) is prevalent in Southern China. Unfortunately, current treatments encounter multidrug resistance (MDR). Overexpression of P-glycoprotein (P-gp), resulting the efflux chemotherapy drugs, one significant mechanisms causing MDR. d-α-Tocopheryl poly(ethylene glycol) 1000 succinate (TPGS) has been demonstrated to effectively inhibit P-gp expression. The objectives this study are improve tumor MRI imaging, optimize docetaxel (DOC) administration, and target overcome...

10.1021/acsomega.4c07132 article EN ACS Omega 2024-12-09

Objectives The aim of the present study was to explore magnetic resonance imaging correlates performance instrumental activities daily living ( IADL ) in patients with A lzheimer's disease combined cerebrovascular disease. Methods total 66 formed sample. Two regression models were constructed find . Model 1 only included clinical variables and model 2 both variables. Results In 1, as dependent variable, M ini‐Mental S tate E xamination MMSE score, P hysical elf‐ aintenance cale score at...

10.1111/ggi.12323 article EN Geriatrics and gerontology international/Geriatrics & gerontology international 2014-08-11

Motivation: To determine an effective individualized treatment decision for lung cancer patients with brain metastasis (BrM) to receive targeted therapy. Goal(s): we developed MRI-based nomogram that can predict the response of BrM therapy using multi-center data. Approach: Clinical predictors, radiomics and deep learning features extracted from baseline MR images were incorporated establish LASSO logistics coefficients. Results: The accurately 6-month 12-month responses across training...

10.58530/2024/0864 article EN Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition 2024-11-26

Motivation: There is currently no reliable tool to predict postoperative recurrence for patients who undergo surgery brain metastases (BrMs). Goal(s): This study aimed develop and externally validate a prognostic model intracranial recurrence-free survival (RFS) lung cancer receiving BrM surgery. Approach: A combined model-based nomogram was developed by incorporating clinical structural MRI predictors, radiomics deep signatures extracted from MR images. Results: The predicted accurately RFS...

10.58530/2024/3769 article EN Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition 2024-11-26

Thyroid cancer (TC) is an extremely prevailing malignant endocrine tumor. Therefore, effective diagnostic tools are necessary. This study explored the application value of dual-source computed tomography (DSCT) in TC diagnosis and biological behavior assessment.This retrospectively selected 68 patients another 74 benign with thyroid adenoma, nodular goiter, or adenomatous hyperplasia. All were confirmed by pathological examination underwent DSCT examination. The iodine concentration (IC)...

10.1002/jcu.23413 article EN Journal of Clinical Ultrasound 2022-12-20

<title>Abstract</title> Background Smoking cessation can effectively reduce the risk of death, alleviate respiratory symptoms, and decrease frequency acute exacerbations in patients with chronic obstructive pulmonary disease (COPD). Effective smoking strategies are crucial for prevention treatment COPD. Currently, clinical interventions based on theoretical frameworks being increasingly used to help quit have shown promising results. However, theory-guided not been systematically evaluated...

10.21203/rs.3.rs-3118146/v1 preprint EN cc-by Research Square (Research Square) 2023-07-24

Abstract Background: Susceptibility weighted imaging (SWI) provides a rough assessment of tissue perfusion with the prominent hypointense cortical veins in ischemic territory due to increased concentration deoxyhemoglobin. We aimed evaluate whether asymmetrical vein sign (APCVS) on SWI can predict early neurological deterioration (END) acute stroke patients severe intracranial arterial stenosis or occlusion (SIASO). Results: One hundred and nine SIASO who underwent were retrospectively...

10.21203/rs.3.rs-25393/v1 preprint EN cc-by Research Square (Research Square) 2020-05-11

Abstract Objective: This study was to investigate the diagnostic value of quantitative parameters dual-energy computed tomography (CT) for diagnosing lymph nodes (LNs) metastasis in papillary thyroid cancer (PTC). Methods: PubMed, Cochrane, Embase, Web Science, China Biology Medicine disc, WangFang, VIP, and National Knowledge Infrastructure databases were searched up April 20, 2022. Studies that evaluated CT detectingLNs PTC patients included. The standardized mean difference (SMD) 95%...

10.21203/rs.3.rs-2100565/v1 preprint EN cc-by Research Square (Research Square) 2022-10-19
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