A5065646561- Electromagnetic Fields and Biological Effects
- Magnetic and Electromagnetic Effects
- Spaceflight effects on biology
- Adipose Tissue and Metabolism
- Muscle Physiology and Disorders
- Pluripotent Stem Cells Research
Wright State University
2018-2020
Alternative bone regeneration strategies that do not rely on harvested tissue or exogenous growth factors are needed. One of the major challenges in reconstruction is recreating microenvironment using appropriate combination cells, scaffold, and stimulation to direct differentiation. This study presents a formulation involves use human adipose-derived mesenchymal stem cells (hASCs) three-dimensional (3D) hydrogel scaffold based self-assembled RADA16 peptides containing superparamagnetic iron...
Much of the current understanding on molecular and cellular events adipose developmental biology comes from monolayer cell culture models using preadipocyte lines, although in vivo tissue consists a much more complex three-dimensional microenvironment diverse types, extracellular network, tissue-specific morphological functional features. Added to this fact, preadipocytes, which adipogenesis mechanisms are mostly explored, possess some serious limitations (e.g., time initial subculture...