- Airway Management and Intubation Techniques
- Anesthesia and Sedative Agents
- Phonocardiography and Auscultation Techniques
- Anesthesia and Pain Management
- Music Therapy and Health
- Tracheal and airway disorders
- Trauma Management and Diagnosis
- Bacteriophages and microbial interactions
- Traumatic Brain Injury and Neurovascular Disturbances
- Thyroid Disorders and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Cardiac Imaging and Diagnostics
- Obstructive Sleep Apnea Research
- Olfactory and Sensory Function Studies
- Respiratory Support and Mechanisms
- DNA and Nucleic Acid Chemistry
- Heart Rate Variability and Autonomic Control
- Cardiac, Anesthesia and Surgical Outcomes
- Pediatric Pain Management Techniques
- Medical Imaging Techniques and Applications
- Glycosylation and Glycoproteins Research
- Gaze Tracking and Assistive Technology
- Anesthesia and Neurotoxicity Research
- Radiomics and Machine Learning in Medical Imaging
- Microscopic Colitis
Hanyang University
2025
Exact Sciences (United States)
2024
Korea Advanced Institute of Science and Technology
2015-2022
Chungbuk National University Hospital
1999-2022
Broad Institute
2021
Chungbuk National University
2001-2016
Jeju National University
2011
Ulsan University Hospital
2009
University of Ulsan
2009
Ulsan College
2009
Because of its rapid onset time, recent years have seen an increase in the use ultrasound (US)-guided popliteal sciatic nerve block (PSNB) via subparaneural injection for induction surgical anesthesia. Moreover, below-knee surgery, combined blocks, as opposed to alone, become more common. These blocks often require a large volume local anesthetic (LA), thus increasing risk local-anesthetic systemic toxicity (LAST). Thus, decrease LAST, it is important know minimum effective (MEV) required...
Cognitive impairment is a major comorbidity of chronic obstructive pulmonary disease (COPD), but the underlying mechanisms are not fully understood. In this study, we used resting-state functional magnetic resonance imaging to investigate brain connectivity (FC) abnormalities in patients with COPD and explored correlation between abnormal FC COPD-related clinical parameters. Forty-one COPD, without definite diagnosis cognitive or depression, 30 age- sex-matched controls were recruited. A...
It has been suggested that a thyroglobulin (Tg)-R19K missense mutation may be newly identified cause of human congenital goiter, which is surprising for this seemingly conservative substitution. Here, we have examined the intracellular fate recombinant mutant Tg expressed in COS-7 cells. Incorporation R19K largely blocked secretion, and was approximately 90% degraded intracellularly over 24-h period after synthesis. Before its degradation, Tg-R19K exhibited abnormally increased association...
As the number of elder patients grows, spinal anesthesia for such are increasing significantly. Any effort is needed to use least anesthetic drug maintaining while avoiding hazards cardio-pulmonary complications.American Society Anesthesiologists physical status classification I and II, Forty five elderly (≥ 60 years) who received transurethral resection prostate or bladder tumor were allocated randomly into three treatment groups. The DMT 0.5 group was designed as with dexmedetomidine µg/kg...
In unconscious patients, pupillary light reflex is an indicator of brain damage. the current study, a smartphone application was developed for purpose measuring with aim to determine agreement between measurements using (APP) and penlight (PEN). The APP acquires five sequential photographs camera flash in order stimulate pupil. initial image captured prior flash, subsequent obtained while on. remaining three images are whilst off. Pupillary right assessed 30 healthy subjects PEN. After 10...
Background The present study tested the effect of midazolam administration after sevoflurane anesthesia against emergence agitation in children recovery phase. Methods A total 60 presenting for ophthalmic surgery under were randomly placed four groups from Group I to IV. Before end surgery, we injected normal saline 2 ml and We administered a 2-ml mixture 0.025 mg/kg 0.050 II III respectively. Among patients with scores 4 or 5 peostanesthesia care unit (PACU), IV intravenously given 1-ml up...
Heart diseases associated with living conditions, such as coronary heart disease and hypertension are becoming more complex. If condition didn't get long-term real-time monitoring diagnosis, it may induce sudden disease. As the auscultation is one of most fundamental ways to evaluate functions, a stethoscope can be used auscultate respiratory sounds sounds, diagnose cardiopulmonary disorders other diseases. Therefore, we tried develop smartphone-based system that record sound calculate rate...
Objective : Esophageal stethoscope has the advantage of being non-invasive, easily placed and capability to monitor heart sound. This study was designed determine whether ratio S1 S2 analyzed by esophageal wireless bluetooth transmission can be accurate indicator that express correlation with blood pressure.Total 33 adult male female without cardiac disorder normal rhythm were selected randomly as subjects this Study. Two microphones used one for acquisition sound connecting it while other...
Background One of the main concerns in orbital blowout fracture repair is a narrow operation field, due mainly to innate complex three dimensions orbit; however, deep location and extensive area soft tissue edema can also cause concern. Swelling contents progresses as continues. Mannitol has been used empirically glaucoma, cerebral hemorrhage, compartment syndrome for decompression. The authors adopted mannitol control intraorbital pressure repair. Methods This prospective study included 108...
Visual loss occurring after pediatric cardiac surgery employing cardiopulmonary bypass (CPB) is relatively rare but the risk substantial. Compromised cerebral perfusion due to a CPB related micro-embolization and inflammatory vascular changes as well reduced oxygen carrying capacity in hemodilution hypothermia during might be major contributing factors development of postoperative visual with CPB. A case immediate transient was encountered 21-month-old male who underwent tricuspid valve...
During nasotracheal intubation it is important to have proper pretreatment for nasal mucosa constriction and cavity expanding. Nasal packing of epinephrine gauze widely used as well xylometazoline. The aim this study was compare evaluate the efficacy prophylactic intranasal spray xylometazoline against in expanding cavity.Volunteers (n = 32) their twenties without disease such septal deviation or rhinitis were enrolled study. more patent nostril each subject measured by acoustic rhinometry...
The assembly of proteins in a programmable manner provides insight into the creation novel functional nanomaterials for practical applications. Despite many advances, however, rational protein with an easy scalability terms size and valency remains challenge. Here, simple bottom-up approach to supramolecular tunable is presented. dendrimer-like assembly, simply called "protein dendrimer," constructed through stepwise alternate addition building block protein. Starting from zeroth-generation...
Every operation could have a fire emergency, especially in the case of tracheostomy. When flammable gas meets source heat, danger is remarkable. A tracheal tube filled with high concentration oxygen also great risk factor for fire. Intra-tracheal rare, yet critical emergency catastrophic consequences. Thus, numerous precautions are taken during tracheostomy like, use special to prevent laser damage, ballooning normal saline instead air, and dilution FiO(2) helium or nitrogen. Since first...
A hyperventilation attack is common in people with overanxiety and nervous prostration.However, persistent can cause many severe complications.Although there have been case reports studies on the attack, has no report that occured during recovery from general anesthesia.We experienced a unique of anesthesia.The patient was previously healthy 18 years old female who did not any other history or psychogenic problems.During anesthesia recovery, she suddenly hyperventilated (respiratory rates >...
Abstract Background: A multi-biomarker blood test has the potential to detect cancers in a broad range of organ types and stages. We previously trained independently assessed performance two biomarker classes (methylation protein; MP) for multi-cancer early detection (MCED) prospectively collected study (Cancer Res,2024;84(7Supp):LB100). Here, we addition somatic mutation reflex approach samples with initially negative MP-results (MP-reflex; MP-r). Methods: This included 3,160 (739 cancer...