A5021841981- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Inflammatory Bowel Disease
- Microscopic Colitis
- Eosinophilic Esophagitis
- Liver Disease Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Celiac Disease Research and Management
- Gastric Cancer Management and Outcomes
- Neuroendocrine Tumor Research Advances
- Diverticular Disease and Complications
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Bariatric Surgery and Outcomes
- Gastroesophageal reflux and treatments
- Gastrointestinal Tumor Research and Treatment
- Gallbladder and Bile Duct Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Immunodeficiency and Autoimmune Disorders
- Autoimmune and Inflammatory Disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Intestinal Malrotation and Obstruction Disorders
- Liver Disease and Transplantation
- Liver Diseases and Immunity
Huron Gastro
2023-2024
Trinity Health
2023-2024
Damascus University
2023
Cleveland Clinic
2018-2022
West Virginia University
2020
University Hospitals of Cleveland
2017-2019
Case Western Reserve University
2017-2019
University Hospitals Cleveland Medical Center
2017
Royal Stoke University Hospital
2014
University of Jordan
2014
There are limited data regarding the factors associated with hepatocellular carcinoma (HCC) in non-alcoholic fatty liver disease (NAFLD) patients without cirrhosis. We sought to determine prevalence and HCC NAFLD or cirrhosis.Adults (June 2015 May 2020) were identified using electronic health record database (Explorys Inc, Cleveland, OH) from 26 major integrated US healthcare systems. The of was calculated. Multivariable analyses adjusting for covariates performed evaluate risk presence...
Abstract Background Chronic inflammation is a key factor for the development of colorectal cancer (CRC) among patients with inflammatory bowel disease (IBD). Despite increased use biologic agents in IBD, their impact on carcinogenesis remains unclear. With large database, we sought to describe effect biologics CRC IBD. Methods We evaluated multicenter database (Explorys) consisting electronic medical records from several U.S. hospitals between 1999 and 2020. A cohort diagnosis IBD was...
Liver transplant (LT) patients represent one of the largest immunosuppressed cohorts. However, outcomes coronavirus disease (COVID-19) in this population remain poorly defined although liver injury has been reported with COVID-19.1Zhang C. et al.Lancet Gastroenterol Hepatol. 2020; 5: 428-430Abstract Full Text PDF PubMed Scopus (1335) Google Scholar We sought to examine characteristics LT infected COVID-19 and study rates hospitalization, mortality, thrombosis, or intensive care unit (ICU)...
Alzheimer disease (AD) affects 5 million Americans and early recognition improves cognitive function. Chronic inflammation gut microbiome alteration are linked to decline which common in inflammatory bowel (IBD). We investigated the association of IBD with development AD. A commercial database (Explorys Inc., Cleveland, OH), an aggregate electronic health records from 26 major US care systems, was surveyed. Cohorts patients Systematized Nomenclature Medicine—Clinical Terms (SNOMED-CT)...
Objective: To explore the safety and benefit from intra-articular autologous platelet lysate (PL) injection in early intermediate knee osteoarthritis. Design: Open-label prospective study. Setting: Laboratory. Patients: Adult patients, aged 35 to 70 years, with a history of chronic pain or swelling on one both knees imaging findings (radiograph magnetic resonance imaging) degenerative changes joint grade I II Kellgren scale were included. Interventions: Autologous PL was given by...
Opportunistic infections (OIs) are more common in patients with inflammatory bowel disease (IBD); however, there have been limited large-scale studies of OIs IBD. We investigated the epidemiological characteristics OI Crohn's (CD) and ulcerative colitis (UC) using a large population-based database.Data were collected from commercial database (Explorys Inc., Cleveland, OH, USA) that provided electronic health records 26 major integrated US care systems 1999 to March 2018. In this data set, we...
Abstract Background and Aim Celiac disease (CD) is a chronic disorder resulting from an immune reaction to gluten in genetically predisposed individuals. Although several studies have linked CD psychiatric diseases, there are limited data on this topic. Using large database, we sought describe the epidemiology of disorders CD. Methods We queried multicenter database (Explorys Inc), aggregate electronic health record 26 major integrated healthcare systems 2016 2020 consisting 360 hospitals...
Chronic pancreatitis (CP) is often associated with poor quality of life. Only a few small associative studies have reported the prevalence mood disorders in CP. Using large database, we sought to describe epidemiology and risk association anxiety depression CP evaluate their outcomes.A multicenter database (Explorys), an aggregate electronic health record data from 26 US healthcare systems, was surveyed. A cohort patients diagnosis between 2014 2019 identified. Within this cohort, rates were...
Gallbladder cancer (GBC) is the most common neoplasm of biliary tract with lowest rates survival. Most GBCs are adenocarcinomas that arise from epithelial lining gallbladder. There limited data in literature regarding epidemiology GBC. Using a large database, we aim to describe using US population database.A multi-institutional database (Explorys Inc., Cleveland, OH, USA) was surveyed. A cohort patients primary malignant gallbladder between 1999-2019 identified. The prevalence rate...
Abstract Objectives RA is a systemic autoimmune disease characterized by persistent joint inflammation. Extra-articular manifestations of can involve different organs including the gastrointestinal (GI) system. Using large database, we sought to describe epidemiology pancreas involvement in RA. Methods We queried multicentre database (Explorys Inc, Cleveland, OH, USA), an aggregate electronic health record data from 26 major integrated US healthcare systems 1999 2019. After excluding...
An important part of training the next generation physicians is ensuring that they are exposed to integral role research plays in improving medical treatment. However, students often do not have sufficient time be trained carry out any projects biomedical and clinical research. Many also fail understand grasp translational as an concept today. In addition, since international affair whereby a student/resident/fellow will likely train many different countries during his/her early years, it...
EUS-guided gallbladder drainage (EUS-GBD) can be used to treat acute cholecystitis in patients with medical comorbidities that prevent definitive operative management. Historically, nonsurgical management of was achieved by way percutaneous drainage.We examined the periprocedural bleeding rate EUS-GBD for using lumen-apposing metal stents 5 high-surgical-risk requiring anticoagulation. Data on nonoperative candidates who underwent were studied retrospectively.There no immediate or delayed...
Objectives A few past studies have found increased utilization of 25-hydroxyvitamin D and prevalence osteoporosis in acute pancreatitis (AP). Our aim was to obtain a survey bone diseases after sentinel episode AP. Methods database (Explorys), an aggregate electronic health record from 26 integrated United States healthcare systems, queried. cohort patients with Systematized Nomenclature Medicine—Clinical Terms diagnosis AP between 2014 2019, excluding selected medical conditions medications...
Sickle cell hepatopathy (SCH) is an inclusive term referring to any liver dysfunction among patients with sickle disease. Acute intrahepatic cholestasis one of the rarest and most fatal presentations SCH. We present 23rd reported case transplantation (LT) for SCH; a rare acute managed LT from hepatitis C virus (HCV) nucleic acid amplification test positive donor.A 29-year-old male past medical history disease presented vaso-occlusive pain crisis. On examination, he had jaundice soft,...