Mohamed M. Gad
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Multiple and Secondary Primary Cancers
- Atrial Fibrillation Management and Outcomes
- Coronary Interventions and Diagnostics
- Cardiac pacing and defibrillation studies
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Pericarditis and Cardiac Tamponade
- Pancreatic and Hepatic Oncology Research
- Acute Myocardial Infarction Research
- Colorectal Cancer Screening and Detection
- Cardiac Arrhythmias and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Ischemic Stroke Management
- Bladder and Urothelial Cancer Treatments
- Lipoproteins and Cardiovascular Health
- Cardiovascular Issues in Pregnancy
- Mechanical Circulatory Support Devices
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Global Cancer Incidence and Screening
Cleveland Clinic
2018-2024
University of North Carolina at Chapel Hill
2019-2024
Baylor College of Medicine
2022-2024
Zagazig University
2024
University Hospitals of Cleveland
2022-2023
Case Western Reserve University
2022-2023
University School
2022-2023
University of Washington
2020-2022
Institute for Health Metrics and Evaluation
2020-2022
Avalon University School of Medicine
2022
<h2>Summary</h2><h3>Background</h3> Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality this are scarce or non-existent in many countries. We estimated the global, regional, national burden CKD, as well cardiovascular gout attributable to impaired function, Global Burden Diseases, Injuries, Risk Factors Study 2017. use term CKD refer that can be directly attributed all stages we function additional risk from...
Oesophageal cancer is a common and often fatal that has two main histological subtypes: oesophageal squamous cell carcinoma adenocarcinoma. Updated statistics on the incidence mortality of cancer, disability-adjusted life-years (DALYs) caused by disease, can assist policy makers in allocating resources for prevention, treatment, care cancer. We report latest estimates these 195 countries territories between 1990 2017, age, sex, Socio-demographic Index (SDI), using data from Global Burden...
Worldwide, both the incidence and death rates of pancreatic cancer are increasing. Evaluation burden its global, regional, national patterns is crucial to policy making better resource allocation for controlling risk factors, developing early detection methods, providing faster more effective treatments.Vital registration, vital registration sample, registry data were used generate mortality, incidence, disability-adjusted life-years (DALYs) estimates. We comparative assessment framework...
Stomach cancer is a major health problem in many countries. Understanding the current burden of stomach and differential trends across various locations essential for formulating effective preventive strategies. We report on incidence, mortality, disability-adjusted life-years (DALYs) due to 195 countries territories from 21 regions between 1990 2017.Estimates GBD 2017 were used analyse DALYs at global, regional, national levels. The rates standardised world population reported per 100 000...
Colorectal cancer (CRC) is the third most common and second leading cause of related deaths in world with an estimated number 1.8 million new cases about 881,000 worldwide 2018. The epidemiology CRC varies significantly between different regions as well age, gender racial groups. Multiple factors are involved this variation, including risk factor exposure, demographic variations addition to genetic susceptibility mutations their effect on prognosis treatment response. In mini-review, we...
Background: Nonrheumatic valvular diseases are common; however, no studies have estimated their global or national burden. As part of the Global Burden Disease Study 2017, mortality, prevalence, and disability-adjusted life-years (DALYs) for calcific aortic valve disease (CAVD), degenerative mitral disease, other nonrheumatic were 195 countries territories from 1990 to 2017. Methods: Vital registration data, epidemiologic survey administrative hospital data used estimate burden using...
High prevalence of diabetes has been reported in the Americas, but no comprehensive analysis burden and related factors for region is available. We aimed to describe type 1 2 that hyperglycaemia Americas from 1990 2019.We used estimates GBD 2019 evaluate adults aged 20 years or older high fasting plasma glucose 25 39 countries territories six regions 2019. The main source estimate mortality attributable chronic kidney disease due was vital registration. Mortality overall (ie, disease)...
Importance Stroke is a leading cause of death and disability in the US. Accurate updated measures stroke burden are needed to guide public health policies. Objective To present estimates ischemic hemorrhagic US 2019 describe trends from 1990 by age, sex, geographic location. Design, Setting, Participants An in-depth cross-sectional analysis Global Burden Disease study was conducted. The setting included time period encompassed for various types strokes, including all intracerebral...
The suicide risk after a new cancer diagnosis remains controversial issue. This study examines the within year diagnosis. is largest to assess recent trends in diagnosis.Data were obtained from Surveillance, Epidemiology, and End Results Program. All patients diagnosed with between 2000 2014 selected. event was defined as death due first diagnosis, who experienced their observed. observed/expected (O/E) ratio assessed well excess per 10,000 person-years determine change comparison general...
The landmark study of durvalumab as consolidation therapy in NSCLC patients (PACIFIC trial) demonstrated significantly longer progression-free survival (PFS) with locally advanced, unresectable non-small cell lung cancer (NSCLC) treated (immunotherapy, IO) after chemoradiotherapy (CRT). In clinical practice the USA, continues to be used across all levels programmed death ligand-1 (PD-L1) expression. While immune therapies have shown promise several cancers, some either do not respond or...
Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden mortality in sub-Saharan Africa (SSA), world not on track to meet targets set for ending epidemic by Joint United Nations Programme HIV/AIDS (UNAIDS) Sustainable Development Goals (SDGs). Precise HIV information critical effective geographic epidemiological targeting prevention treatment interventions. Age- sex-specific prevalence estimates are widely available...
The association between elevated values of reactive oxygen species and a decreased antioxidant capacity defines oxidative stress. Oxidative stress involvement is blamed in many diseases, including obesity. We evaluated levels by FORT (Free Oxygen Radical Testing � levels) FORD Defence value) assays obese subjects vs. controls. were high low patients controls, notably with comorbidities (diabetes, hypertension, dyslipidaemia, coronary heart disease, anaemia, hepatic steatosis). found positive...