A5072662795- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Advanced X-ray and CT Imaging
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Immune Cell Function and Interaction
- Immunodeficiency and Autoimmune Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Peptidase Inhibition and Analysis
- COVID-19 Clinical Research Studies
- Blood Pressure and Hypertension Studies
- Ocular Diseases and Behçet’s Syndrome
- Tuberculosis Research and Epidemiology
- Liver Disease Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Autoimmune and Inflammatory Disorders
- Healthcare Systems and Reforms
- Global Health Care Issues
- Cardiovascular Health and Disease Prevention
- Renal function and acid-base balance
- Atherosclerosis and Cardiovascular Diseases
- Cytokine Signaling Pathways and Interactions
Vanderbilt University Medical Center
2022-2025
Johns Hopkins University
2020-2024
Universal Scientific Education and Research Network
2016-2024
Johns Hopkins Medicine
2021-2023
Vanderbilt Health
2023
Johns Hopkins Hospital
2021-2022
University of Baltimore
2022
Tehran University of Medical Sciences
2016-2021
Universitätsklinikum des Saarlandes
2021
Children's Medical Center
2017-2020
High prevalence of diabetes has been reported in the Americas, but no comprehensive analysis burden and related factors for region is available. We aimed to describe type 1 2 that hyperglycaemia Americas from 1990 2019.We used estimates GBD 2019 evaluate adults aged 20 years or older high fasting plasma glucose 25 39 countries territories six regions 2019. The main source estimate mortality attributable chronic kidney disease due was vital registration. Mortality overall (ie, disease)...
Both left atrial and ventricular functional parameters influence the prognosis of patients with cardiovascular diseases. This study aimed to investigate prognostic value a novel atrioventricular coupling index (LACI) in population without history diseases at baseline. Participants Multi-Ethnic Study Atherosclerosis who underwent baseline magnetic resonance were analyzed. LACI was defined by ratio end-diastolic volume divided volume. Cox proportional hazard models used evaluate association...
Purpose Conventional CT technology yields only modest accuracy of coronary artery stenosis assessment in severely calcified lesions. Reported herein are this study's initial observations on the potential ultra-high-resolution (UHR-CT) for evaluating arterial Materials and Methods Fifteen patients 45 years age or older, with history disease, referred invasive angiography, were prospectively enrolled. Patients underwent UHR-CT within 30 days prior to cardiac catheterization. Image noise levels...
Background Obesity and sarcopenia are associated with mortality in chronic obstructive pulmonary disease (COPD). Routine chest CT examinations may allow assessment of obesity by soft-tissue markers for predicting risks mortality. Purpose To investigate associations between subcutaneous adipose tissue (SAT), intermuscular (IMAT), pectoralis muscle (PM) index from participants COPD. Materials Methods In this secondary analysis a prospectively enrolled cohort the Multi-Ethnic Study...
Breast cancer is the most common among women, causing considerable burden and mortality. Demographic lifestyle transitions in low low-middle income countries have given rise to its increased incidence. The successful management of relies on evidence-based policies taking into account national epidemiologic settings. We aimed report subnational trends breast incidence, mortality, years life lost (YLL) mortality incidence ratio (MIR) since 1990. As part National Subnational Burden Diseases...
Abstract Aims By 2030, we seek to reduce premature deaths from non-communicable diseases, including ischaemic heart disease (IHD), by one-third reach the sustainable development goal (SDG) target 3.4. We aimed investigate quality of care IHD across countries, genders, age groups, and time using Global Burden Diseases Study (GBD) 2017 estimates. Methods results did a principal component analysis on mortality incidence ratio, disability-adjusted life-years (DALYs) prevalence years life lost...
Background: Childhood cancer is a double-edged sword, considering its high rate of response to treatment despite vulnerability develop future malignancies in survivors. Thus, multidisciplinary preventive, curative, and supportive strategies must be incorporated childhood care that require understanding the distribution trend target population. In this article, we aimed report national subnational trends incidence Iran from 1990 2016, mortality/incidence ratio (MIR), which, our knowledge,...
Sex hormone (SH) imbalances have been linked to a higher risk of heart failure in both sexes. However, mechanisms that underlie this relationship remain unclear. We examined the association baseline SH with interstitial and replacement myocardial fibrosis MESA (Multi-Ethnic Study Atherosclerosis) using cardiac magnetic resonance (CMR) T1 mapping late gadolinium enhancement (LGE). The purpose study was assess link between sex levels cohort CMR. A total 2,324 participants (men postmenopausal...
Background and Aims: Genetic testing is recommended for select patients with atrial fibrillation (AF). The aims of this study were to define the results genetic evaluation its therapeutic impact referred a dedicated AF precision medicine clinic. Methods: Patients diagnosed before age 60 candidates referral. In addition standard history, physical exam, ECG, included 3-generation pedigree, cardiac imaging, ambulatory monitoring, clinical cardiomyopathy/arrhythmia panel. Results: 264...
With an increase in the incidence and prevalence of non-rheumatic valvular heart diseases (NRVHDs), having a proper understanding disease current status terms quality care healthcare access can considerably affect further planning for system.In this study, we aimed to evaluate compare equity concerning NRVHDs gender sociodemographic index (SDI) using newly proposed index.We obtained primary measures (e.g. incidence) from Global Burden Disease (GBD) data about NRVHD 1990 2017 calculate...
Sex hormones associated with both the left atrial (LA) and ventricular (LV) structures in women, but association of menopause status atrioventricular coupling is not established.To assess prognostic value a index (LACI) peri-menopausal women without history cardiovascular disease (CVD).In all participating MESA study baseline MRI, LACI was measured as ratio LA end-diastolic volume to LV volume. Cox models were used between outcomes fibrillation (AF), heart failure (HF), coronary (CHD) death,...
Background Rare pathogenic variants in cardiomyopathy (CM) genes can predispose to cardiac remodeling or fibrosis. We studied the carrier status for such adults without clinical cardiovascular disease (CVD) whom MRI (CMR)-derived measures of myocardial fibrosis were obtained Multi-Ethnic Study Atherosclerosis (MESA). Objectives To identify CM-associated and assess their relative prevalence participants with extensive by CMR. Methods MESA whole-genome sequencing data was evaluated capture ( n...
Common genetic variants are associated with risk for hypertrophic cardiomyopathy and dilated left ventricular (LV) traits. Whether these myocardial fibrosis, an important pathophysiological mediator of cardiomyopathy, is unknown.