A5077880208- Neuroscience and Neuropharmacology Research
- Alzheimer's disease research and treatments
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Colorectal Cancer Screening and Detection
- Cholinesterase and Neurodegenerative Diseases
- Neuroendocrine regulation and behavior
- Nerve injury and regeneration
- Neurogenesis and neuroplasticity mechanisms
- COVID-19 Clinical Research Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Anesthesia and Neurotoxicity Research
- Memory and Neural Mechanisms
- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Medicinal Plants and Neuroprotection
- Biochemical effects in animals
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Sleep and Wakefulness Research
- Dermatological and COVID-19 studies
- SARS-CoV-2 and COVID-19 Research
- Cardiac Arrest and Resuscitation
- Mesenchymal stem cell research
Ardabil University of Medical Sciences
2013-2024
Tehran University of Medical Sciences
2015-2023
University of Sharjah
2022
Shariati Hospital
2015-2021
University of California, Irvine
2019-2021
Columbia University
2019
Tabriz University of Medical Sciences
2010-2017
Digestive Disease Research Institute
2015
Digestive Health Research Institute
2015
Stomach cancer is a major health problem in many countries. Understanding the current burden of stomach and differential trends across various locations essential for formulating effective preventive strategies. We report on incidence, mortality, disability-adjusted life-years (DALYs) due to 195 countries territories from 21 regions between 1990 2017.Estimates GBD 2017 were used analyse DALYs at global, regional, national levels. The rates standardised world population reported per 100 000...
To investigate the impact of gender on multimorbidity in northern Iran.
Ischemia/Reperfusion (IR) injury mainly causes the increase of enzymes involved in myocytes including CK-MB (creatine kinase-MB) isoenzyme and LDH (lactate dehydrogenase). Leakage from myocardial tissues to blood is indicator acute infarction. The aim this study was assess effect HEMADO on IR its relationship with mitochondrial ATP-sensitive K+ channels (mitoKATP) rat heart.Twenty eight male Wistar rats (250-300g) were divided into four groups (seven members each group): control (without...
Alzheimer's disease (AD) is an age-related neurodegenerative linked with increased production and/or deposition of amyloid-beta (Aβ) in the brain. The aim present study was to investigate possible neuroprotective effect troxerutin on animal model disease. Alzheimer induced by a single dose intracerebroventricular (ICV) injection Aβ 1-42 (5 nmol/5 µl). Thereafter, (300 mg/kg) gavaged for 14 days. hippocampal malondialdehyde (MDA) levels and enzymatic activities superoxide dismutase (SOD),...
Acute pancreatitis is a serious complication of endoscopic retrograde cholangiopancreatography (ERCP). The aim this noninferiority study was to evaluate the effectiveness pancreatic duct (PD) stenting plus pharmacological prophylaxis vs. alone in prevention post-ERCP (PEP) high risk patients.In randomized, controlled, double-blind, trial, patients at developing PEP were randomly allocated (rectal indomethacin, sublingual isosorbide dinitrate, and intravenous hydration with Ringer's lactate)...
Why layers II/III of entorhinal cortex (EC) deteriorate in advance other regions during the earliest stages Alzheimer's disease is poorly understood. Failure retrograde trophic support from synapses to cell bodies a common cause neuronal atrophy, and we accordingly tested for early-life deterioration projections rodent layer II EC neurons. Using electrophysiology quantitative imaging, changes terminals young adulthood were evaluated male rats mice. Field excitatory postsynaptic potentials,...
Cardiovascular risk factors, including diabetes mellitus may attenuate the cardioprotection by postconditioning. This study aimed to investigate cardioprotective effect of ischemic-postconditioning (IPostC) against ischemia/reperfusion injury in normal and chronically type-1 diabetic rats mitochondrial permeability transition pore (mPTP) inhibition this field.Diabetes was induced a single intra-peritoneal injection streptozotocin (50 mg/kg) Wistar male (250-300 g). After 8 weeks, hearts...
Abstract Cognitive impairments affect millions of people worldwide with an increasing prevalence. Research on their etiology and treatment is developing, nevertheless significant gaps remain. Trientine (TETA), as a copper chelator, has been shown to have beneficial effects in different human chronic diseases such diabetic cardiomyopathy neuropathy. Here, we examined the impact TETA AlCl3-induced neurocognitive dysfunctions molecular changes hippocampus rats. Thirty-six male Wistar rats...
Gamma-aminobutyric acid (GABA) plays an inhibitory role in the mature brain, and has a complex bidirectional effect different parts of immature brain which affects proliferation, migration differentiation neurons during development. There is also increasing evidence suggesting that activation or blockade GABA-A receptors early life can induce behavioral abnormalities adulthood. We investigated whether neonatal by bicuculline alter anxiety- depression-like behaviors, body weight, food intake,...
Introduction: COVID 19 is a global pandemic declared by the WHO on 30/01/2020. The first case was in Burundi 31 March 2020. objective of our work to study liver function abnormalities during SARS CoV2 and their impact prognosis disease. Methodology: This retrospective, single-center, descriptive analytical that took place over period 2 years (2020-2021). involved 115 patients who were hospitalized at BUMEREC Hospital. Results: 155 had test hospitalization. mean age 60 with an interval...
BACKGROUND Although Heller myotomy is one of the most effective treatments for achalasia, it may be associated with early or late symptom relapse in some patients. Therefore, additional treatment required to achieve better control symptoms.To evaluate safety and efficacy pneumatic balloon dilation (PBD) patients after myotomy. METHODS Thirty six post-myotomy were evaluated from 1993 2013. Six excluded analysis because comorbid diseases epiphrenic diverticula. treated PBD. Primary outcome was...
Objective We aimed to measure cancer knowledge and feasibility of a screening colonoscopy among cohort individuals at higher risk colon cancer. Methods This study was conducted as part an ongoing cohort, in which first degree relatives (FDRs) patients with are invited participate free charge colonoscopy. enrolled 1017 FDRs the between 2013 2014 measuring their data on demographics, uptake. A p value <0.05 considered statistically significant. Results The relative's mean age 48.7 years....