A5026026149- Extracellular vesicles in disease
- Viral Infections and Vectors
- Marine Biology and Environmental Chemistry
- MicroRNA in disease regulation
- Nanoplatforms for cancer theranostics
- Pulmonary Hypertension Research and Treatments
- Microplastics and Plastic Pollution
- Circular RNAs in diseases
- Travel-related health issues
- Selenium in Biological Systems
- Polymer Surface Interaction Studies
- Crustacean biology and ecology
- Curcumin's Biomedical Applications
- Advanced Nanomaterials in Catalysis
- Nicotinic Acetylcholine Receptors Study
- Solar-Powered Water Purification Methods
- Polyamine Metabolism and Applications
- Macrophage Migration Inhibitory Factor
- Marine Biology and Ecology Research
- Marine Toxins and Detection Methods
- Biochemical Acid Research Studies
- Genomics, phytochemicals, and oxidative stress
Naval University of Engineering
2025
National University of Defense Technology
2017-2020
Abstract Sulfur mustard (SM) is a blister‐producing chemical warfare agent which could lead to cascade of systemic damage, especially severe acute lung injury. Oxidative stress considered be vital processes for the SM toxicity mechanism. We previously proved therapeutic effect exosomes derived from bone marrow mesenchymal stromal cells in promoting repair alveolar epithelial barrier and inhibiting apoptosis. However, key functional components underlying mechanisms have not been fully...
Abstract Acute lung injury (ALI) is a severe respiratory disease with high mortality rate. The integrity of the pulmonary endothelial barrier influences development and prognosis ALI. Therefore, it has become an important target for ALI treatment. Extracellular vesicles (EVs) are promising nanotherapeutic agents against Herein, endothelium‐derived engineered extracellular (eEVs) that deliver microRNA‐125b‐5p (miRNA‐125b) to tissues exerting protective effect on reported. eEVs modified...
Abstract Background Sulfur mustard (SM) is a highly toxic chemical warfare agent that has caused numerous casualties during wars and conflicts in the past century. Specific antidotes or therapeutic strategies are rare due to complicated mechanism of toxicity, which still awaits elucidation. Clinical data show acute lung injury (ALI) responsible for most mortality morbidity after SM exposure. Extracellular vesicles natural materials participate intercellular communication by delivering...
Extracellular vesicles (EVs) are lipid bilayer nanoparticles naturally released from cells, playing a crucial role in intercellular communication. They modulate gene expression and regulate physiological pathological processes, including acute lung injury (ALI) respiratory distress syndrome (ARDS). Research has shown that EVs contain variety of active components, biocompatible small size, do not trigger immune rejection, making the infusion exogenous promising therapeutic tool. With further...
Abstract Background: Sulfur mustard (SM) is a blister-producing chemical warfare agent which could lead to cascade of systemic damage, especially severe acute lung injury. Oxidative stress considered be vital processes for the SM toxicity mechanism. We previously proved therapeutic effect exosomes derived from bone marrow mesenchymal stromal cells in promoting repair alveolar epithelial barrier and inhibiting apoptosis. However, key functional components underlying mechanisms have not been...