Jay Shah

ORCID: 0000-0003-0429-5021
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About
Contact & Profiles
Research Areas
  • Cardiac Valve Diseases and Treatments
  • Acute Ischemic Stroke Management
  • Atrial Fibrillation Management and Outcomes
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Structural Anomalies and Repair
  • Hemoglobin structure and function
  • Photosynthetic Processes and Mechanisms
  • Plant responses to water stress
  • Cerebrovascular and Carotid Artery Diseases
  • Peripheral Artery Disease Management
  • Spinal Fractures and Fixation Techniques
  • Meningioma and schwannoma management
  • Opioid Use Disorder Treatment
  • Health Systems, Economic Evaluations, Quality of Life
  • Venous Thromboembolism Diagnosis and Management
  • Sports injuries and prevention
  • Urological Disorders and Treatments
  • Spine and Intervertebral Disc Pathology
  • Congenital Heart Disease Studies
  • Pituitary Gland Disorders and Treatments
  • Cardiac Arrhythmias and Treatments
  • Total Knee Arthroplasty Outcomes
  • Intracranial Aneurysms: Treatment and Complications
  • Orthopaedic implants and arthroplasty
  • Cardiac pacing and defibrillation studies

Mercy St. Vincent Medical Center
2017-2024

University of California, Irvine
2020-2024

Jersey City Medical Center
2020-2024

Franciscan Health
2024

Solapur University
2024

HCG Cancer Hospital
2024

University of California, San Francisco
2010-2023

The University of Texas Health Science Center at San Antonio
2023

Mercy Health
2022-2023

B.J. Medical College
2023

Nitric oxide (NO) is a free radical molecule involved in signalling and hypoxic metabolism. This work used the nitrate reductase double mutant of Arabidopsis thaliana (nia) studied metabolic profiles, aconitase activity, alternative oxidase (AOX) capacity expression under normoxia hypoxia (1% oxygen) wild-type nia plants. The roots plants accumulated very little NO as compared to which exhibited ∼20-fold increase emission low oxygen conditions. These data suggest that production either...

10.1093/jxb/ers053 article EN Journal of Experimental Botany 2012-02-01

Significance The primary cilium, an antenna-like extension on the surface of many cells, is considered essential for growth factor and morphogen reception transduction. Here we asked, what function cilia that projects from apical neural stem cells (NSCs) into ventricle? Surprisingly, removal fetal early postnatal NSCs had little effect forebrain development. Primary cilia, however, were in a restricted region major germinal niche, ventricular–subventricular zone. Our data are consistent with...

10.1073/pnas.1321425111 article EN Proceedings of the National Academy of Sciences 2014-08-11

Factor VIII (FVIII) and factor V (FV) are homologous coagulation cofactors sharing a similar domain organization (A1-A2-B-A3-C1-C2) both extensively glycosylated within their B-domains. In mammalian cell expression systems, compared with FV, the FVIII primary translation product is inefficiently transported out of endoplasmic reticulum. Here we show that degraded by lactacystin-inhibitable pathway, implicating cytosolic 20 S proteasome machinery. Protein chaperones calnexin (CNX)...

10.1074/jbc.273.14.8537 article EN cc-by Journal of Biological Chemistry 1998-04-01

Highlights•High Gli1 expression appears transiently in the dorsal V-SVZ during early postnatal ages•Gli1-expressing RGCs subcallosal generate many oligodendroglial cells•Oligodendrogenesis is SHH dependent•Ectopic activation of SMO increases oligodendrogenesis neonatal and adult miceSummaryNeural stem cells different locations mouse ventricular-subventricular zone (V-SVZ) subtypes olfactory bulb (OB) interneurons. High Sonic hedgehog (SHH) signaling ventral regulates production specific...

10.1016/j.stemcr.2015.08.013 article EN cc-by-nc-nd Stem Cell Reports 2015-09-24

Transenteric drainage of a pancreatic fluid collection (PFC) with poor adherence to the bowel wall risks leakage and perforation. Elimination tract dilation use fully covered self-expanding metal stent (FCSEMS) may improve safety. We evaluated endoscopic ultrasound (EUS)-guided PFCs using one-step access device followed by placement FCSEMS. Eighteen patients (12 males; median age 50) (median size 135 mm) meeting criteria for indeterminate were enrolled. After 7 - 10 days, FCSEMSs removed...

10.1055/s-0032-1309839 article EN Endoscopy 2012-07-12

Hypersensitivity reactions are common adverse drug (ADRs) associated with antiepileptics. Carbamazepine is one of the routinely prescribed drugs for treatment epilepsy and neuropathic pain. ADRs due to carbamazepine range from mild maculopapular rash severe anticonvulsant hypersensitivity syndrome (AHS). AHS triad fever, rash, internal organ involvement occurring 1-8 weeks after exposure an (1 in 1,000 10,000 exposures). Spontaneously reported three cases AHS-drug induced by discussed here....

10.4103/0976-500x.124428 article EN Journal of Pharmacology and Pharmacotherapeutics 2014-01-04

Multidisciplinary patient-reported outcomes are a critical part of assessing patients to better understand their well-being during treatment. The use multidisciplinary is recommended in many areas medicine. Patient-Reported Outcomes Measurement Information System-29 (PROMIS-29) has been utilized as common measurement language across universally relevant domains, including pain, mood, sleep, social participation, and function. Retrospective analysis prospectively collected data was performed....

10.1007/s40122-021-00238-z article EN cc-by-nc Pain and Therapy 2021-02-23

Background Transcatheter aortic valve replacement (TAVR) is an alternative for surgically inoperable patients with severe stenosis. Advanced kidney disease may significantly affect outcomes in treated TAVR and surgical (SAVR). Hypothesis associated better in‐hospital compared SAVR advanced disease. Methods We identified our sample from the National Inpatient Sample between 2012 2014, using International Classification of Diseases, Ninth Revision, Clinical Modification codes. included chronic...

10.1002/clc.22806 article EN Clinical Cardiology 2017-11-01

Introduction: In stroke clots, neutrophil extracellular traps (NETs) promote thrombosis, enhance clot stability, and decrease amenability to thrombectomy thrombolysis. Objective: We examine the relationship between NET enrichment mechanical characteristics, radiomics, histological microstructure. Methods: White blood cells (WBCs) were concentrated from human donor whole blood. Platelet-rich plasma red (RBCs) isolated by centrifugation mixed with WBCs produce 0%, 20%, 40% RBC analogs....

10.1161/str.56.suppl_1.tp366 article EN Stroke 2025-01-30

This case report describes the successful management of a bilateral mandibular body fracture in dog following traumatic fight, treated resource-limited rural clinic Nepal. With no access to veterinary surgical facilities, multidisciplinary team—including doctor, oral and maxillofacial surgeon, dental surgeons—performed open reduction internal fixation using intraosseous wiring. The intervention restored function controlled bleeding, demonstrating effectiveness cross-disciplinary...

10.20944/preprints202505.1732.v1 preprint EN 2025-05-22
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