A5054797441- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Wound Healing and Treatments
- Advanced Drug Delivery Systems
- Computational Drug Discovery Methods
- Genetics, Bioinformatics, and Biomedical Research
- Drug Solubulity and Delivery Systems
- Analytical Methods in Pharmaceuticals
- Bioinformatics and Genomic Networks
- Cholinesterase and Neurodegenerative Diseases
- Pharmacy and Medical Practices
- Phytochemicals and Medicinal Plants
- Nanoplatforms for cancer theranostics
- Advanced Cellulose Research Studies
- Context-Aware Activity Recognition Systems
- Psoriasis: Treatment and Pathogenesis
- Tea Polyphenols and Effects
- Carbon and Quantum Dots Applications
- Medicinal Plants and Neuroprotection
- Pharmacological Effects of Natural Compounds
- Characterization and Applications of Magnetic Nanoparticles
- Medical and Biological Ozone Research
- 3D Printing in Biomedical Research
- RNA Interference and Gene Delivery
- Artificial Intelligence in Healthcare and Education
Mittal hospital
2015
Abstract: Cancer remains a formidable global health challenge, necessitating innovative therapeutic strategies. Traditional small-molecule inhibitors often face limitations in selectively targeting diseaseassociated proteins, leading to side effects and incomplete responses. Proteolysistargeting chimeras (PROTACs) turned out be promising approach address these challenges. Unlike traditional inhibitors, PROTACs leverage the cellular ubiquitin-proteasome system degrade disease-associated...
Abstract: Self-assembling structures that look similar to viruses in broad terms but do not contain viral genetic material are known as virus-like particles. These particles, made up of structural proteins, can have size, shape, and surface characteristics natural viruses. The breakthrough potential or VLPs, a novel cancer therapy strategy is explored this article. Starting with describing the problems facing today, emphasis moves an in-depth study including their different sizes, shapes,...
Abstract: Superparamagnetic iron oxide nanoparticles have gained considerable attention in drug delivery due to their superparamagnetic characteristics. SPIONs a greater surface-to-volume ratio, size, superficial chemistry, and characteristics, which allow them be covered by external magnetic fields. These properties make promising for systems. A great advantage of the characteristics is properties. are thoroughly demagnetized when field electromagnet pulled out. permit targeted particular...
Aims: To check the release efficacy of active pharmaceutical ingredients from tablet dosage form using synthetic and natural polymers. Background: Diclofenac sodium in sustained manner tablets was created by Xanthan gum, HPMC, mixed with both polymers to change concentration ratio. The examined for early stage formulation studies such as repose angle, apparent density, compressibility index, some corporal properties like weight variant, friability, content drug. For post-formulation studies,...
Abstract: In recent times, Ethosome has become a new promising pharmaceutical nano-carrier for the development of innovative dermal and transdermal therapies that help in treatment various skin diseases like allergies, urticaria, melisma, eczema, melanoma, other disease. is non-invasive, modified phospholipid-based elastic, soft vesicular with high ethanol content. Ethanol this formulation facilitates rapid penetration drug into accelerating cell membrane lipid fluidity. After permeation...
Host anti-viral factors are crucial for controlling HIV infection, but their role remains largely unknown due to bias in previous large-scale studies. HIV-1 infection untreatable unanticipated infected cells. A large amount of OMIC data and functional genomics screening have gathered the prose public records. Recent years seen publication interacting analyzes related OMICs data, which recognized different types molecular networks, including HIV-human protein-protein interaction gene...
A simple, specific, sensitive and rapid Reverse phase high performance liquid chromatographic (RP-HPLC) method has been developed validated for the quantification of Metoprolol Tartrate in small volumes rabbit plasma. The was further extended its pharmacokinetic studies plasma samples after transdermal oral administration. Biological sample preparation involving simple extraction with organic solvent, followed by dilution mobile adopted to eliminate any solvent effects. proven be linear over...
Abstract: Drug delivery through the blood-brain barrier (BBB) is one of key challenges in modern era medicine due to highly semipermeable characteristics BBB that restrict entry various drugs into central nervous system (CNS) for management brain disorders. Drugs can be easily incorporated carbon nanocarriers cross bloodbrain barrier. Numerous have been developed, including polymeric nanoparticles, lipid-based etc. Among these, nanostructures could superior their easier penetration and...
Abstract: In today’s molecular medicine, delivering therapeutics through the blood-brain barrier to manage neurological disorders remains a challenge. This is one of barriers, which could be potentially solved by nanotechnology; specifically, nanosuspensions are cited most versatile and effective ways. Nanosuspensions submicron size new approach for enhancing drug solubility, permeability barrier, aspect that contributes bioavailability. work reveals problems connected with penetration...