A5100336558- Anaerobic Digestion and Biogas Production
- Wastewater Treatment and Nitrogen Removal
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Membrane Separation Technologies
- Diet and metabolism studies
- Constructed Wetlands for Wastewater Treatment
- Pulmonary Hypertension Research and Treatments
- Traffic Prediction and Management Techniques
- Signaling Pathways in Disease
- Cardiovascular Health and Risk Factors
- Building Energy and Comfort Optimization
- Mitochondrial Function and Pathology
- Obesity, Physical Activity, Diet
- Hormonal Regulation and Hypertension
- Heme Oxygenase-1 and Carbon Monoxide
- Cardiovascular Function and Risk Factors
- Nutritional Studies and Diet
- Urban Heat Island Mitigation
- Viral Infections and Immunology Research
- Cardiac Health and Mental Health
- Macrophage Migration Inhibitory Factor
- Microbial Metabolic Engineering and Bioproduction
- Smart Grid Energy Management
- Energy Efficiency and Management
- Eicosanoids and Hypertension Pharmacology
Chongqing University
2021-2025
Sun Yat-sen University
2024-2025
Beijing University of Technology
2024
Monash University
2022-2023
Tianjin University
2021
Short sleep duration and poor quality have been epidemiologically associated with cardiometabolic disorders. However, limited research has examined the relationship between prolonged latency, an increasingly prevalent disorder, hypertension. Approximately 25% of residents in 4 provincial-level administrative divisions (PLADs) southern China experienced latency. Both occasional habitual latency were significantly increased odds Given increasing prevalence hypertension, health initiatives...
Abstract Background Prolonged sedentary time is a strong risk factor for insulin resistance. Recent evidence indicates that gut microbiota may influence the regulation of sensitivity and demonstrates distinct profile between physically active individuals. However, whether how microbial metabolism mediates progression resistance induced by prolonged remains unclear. Methods 560 male participants without hypoglycaemic therapy were included, was evaluated using Homeostatic Model Assessment...
Stimuli-responsive hydrogels, including photo-responsive, magnetic-responsive, thermo-responsive, and enzyme-responsive systems, have emerged as promising biomaterials for nerve repair regeneration. This paper encapsulates recent developments in the utilization of intelligent hydrogels healing, emphasizing their regenerative capabilities principal limitations identified current literature data. To highlight potential repair, further analysis is provided on innovative applications advanced...
Background and Purpose Inactivation of Cys 674 (C674) in the sarcoplasmic/endoplasmic reticulum Ca 2+ ATPase 2 (SERCA2) causes intracellular accumulation, which activates calcineurin‐mediated nuclear factor activated T‐lymphocytes (NFAT)/NF‐κB pathways, results phenotypic modulation smooth muscle cells (SMCs) to accelerate angiotensin II‐induced aortic aneurysms. Our goal was investigate mechanism involved. Experimental Approach We used heterozygous SERCA2 C674S knock‐in (SKI) mice, where...
Pulmonary hypertension (PH) is a life-threatening disease characterized by pulmonary vascular remodeling, in which hyperproliferation of artery smooth muscle cells (PASMCs) plays an important role. The cysteine 674 (C674) the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase 2 (SERCA2) critical redox regulatory to regulate SERCA2 activity. Heterozygous C674S knock-in mice (SKI), where one copy C674 was substituted serine represent partial oxidative inactivation, developed significant remodeling...
This study evaluated the performance of limited calcium peroxide (CaO2) addition in maintaining system stability anaerobic digestion using lignocellulose biomass as a substrate at high organic load rates. Results showed that an overloaded digester, which had been on verge collapse, regained its after 20 mg/L CaO2 was periodically added. Especially, significantly reduced volatile fatty acid (VFA) concentration and restored pH levels, thus enhancing methane production from 24.6 ± 0.4 to 80.9...
Substitution of Cys674 (C674) in the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase 2 (SERCA2) causes SERCA2 dysfunction which leads to activated inositol requiring enzyme 1 alpha (IRE1α) and spliced X-box binding protein (XBP1s) pathway accelerating cell proliferation pulmonary artery smooth muscle cells (PASMCs) followed by significant vascular remodeling resembling human hypertension. Based on this knowledge, we intend investigate other potential mechanisms involved dysfunction-induced...
The Cys674 residue (C674) in the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase 2 (SERCA2) is key to maintaining its enzyme activity. irreversible oxidation of C674 occurs broadly aortic aneurysms. Substitution promotes a phenotypic transition smooth muscle cells (SMCs) and exacerbates angiotensin II-induced aneurysm. However, underlying mechanism remains enigmatic.Heterozygous SERCA2 C674S knock-in (SKI) mice, which half was replaced by serine, were used mimic partially thiol. aortas SKI...