Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease. Immune system cells have an important role in RA. Our aim was to investigate the relationship between disease activity, immune-inflammation index (SII), and pan-immune-inflammation value (PIV) levels RA patients. We planned whether these 2 measurements advantage over each other. About 67 patients diagnosed with 49 healthy controls included this study. based on 2010 ACR classification criteria. In cross-sectional study,...

Background: The aim of this study was to analyze thyroid hormones and antibodies, ferritin, vitamins B12 D, adrenal gonadal steroid levels, celiac antibodies in children diagnosed with attention deficit hyperactivity disorder (ADHD) autism spectrum (ASD).

BACKGROUND The purpose of this study was to assess the values mean platelet volume (MPV) in children with attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders (ASDs) determine risk cardiovascular disease these 2 groups. MATERIAL AND METHODS included a total 79 patients ADHD or ASDs controls Van region Turkey. control group subjects matching age sex no ADHD, ASDs, chronic taking vitamins. hematological parameters patients, including MPV, vitamin B12, D, were assessed....

To evaluate the clinical findings, risk factors, therapy and outcome in 946 children with nutritional rickets.This retrospective study included a review of medical records patients rickets between March 2004 2009. Patients who displayed both biochemical inclusion criteria signs/symptoms or radiological signs were study.The present aged 4 months 15 years. Distribution cases showed density December May. The age at diagnosis, two peaks most range 0-23 12.0-15 In infants young children, had been...

Brucellosis produces a variety of nonspecific hematologic abnormalities. Hematologic complications mild anemia and leukopenia have been frequently associated with acute brucellosis, but pancytopenia is less seen. In this study, records children brucellosis aged under or equal to 16 years, admitted Yuzuncu Yil University Hospital between 2004 2010, were analyzed retrospectively. Over time period, 187 patients diagnosed. Twenty-five (13.3%) had during admission hospital. The diagnosis was...

Febrile seizures (FS) are the most common cause of in children. The exact etiopathogenesis is unknown but involves factors like genetic predisposition and alterations levels neurotransmitters some trace elements. study includes 48 consecutive children with FS, 55 healthy age matched control subjects. Calcium, magnesium potassium concentrations febrile group were lower than (p<0.05). Iron Gallium (p<0.01). Serum Selenium (p<0.001), Zinc (p<0.001) Strontium (p0.05). aim present prospective...

The aim of the present study was to hematologic findings 622 cases diagnosed with acute brucellosis. Medical records children brucellosis, admitted Yuzuncu Yil University Hospital over a 6-year period, were analyzed retrospectively. Three hundred ninety-seven (63.8%) patients male and 225 (36.2%) female. mean age 11 years (range, 1 16 y). values as follows: hemoglobin 9.4 (3.4 17) g/dL, hematocrite 28% (12% 50%), leukopenia 2.8 (1.1 33)×10/L, leukocytosis 13.7 platelets 79 (3 972)×10/L. An...

Balneotherapy has been widely used for treatment of chronic low back pain recently. However there are only a few clinical controlled trials on balneotherapy. The aim the present study was to evaluate effects balneotherapy in patients with pain.Sixty lumbar spondylosis were included study. In Group 1, received both and physiotherapy 2, three weeks. intensity evaluated by Visual Analog Scale (VAS) functional disability scored according Revised Oswestry Index (ROI). Spinal mobility assessed...

The aim of this study was to determine the frequency thyroid autoimmunity in second grade primary school students and examine relationship between iodine Hashimoto thyroiditis (HT). This a cohort performed with 1000 students. Urinary levels, antithyroid peroxidase (anti-TPO) antithyroglobulin (anti-Tg) antibodies were determined all children. Children anti-TPO or anti-Tg antibody positivity goiter summoned for detailed examinations. In total, 36 cases (3.6%) diagnosed as HT. found 17.5%...

Objective: The objective of the present study was to determine oxidant and antioxidant status in infants with hyperbilirubinemia and/or kernicterus find whether there is a relationship between bilirubin level oxidant/antioxidant status. Patients: includes 69 full-term newborns (neonates needing phototherapy [Group 1, n = 36] neonates 2, 33]) 25 age-matched healthy newborn. Results: Plasma total capacity (TAC) serum (TOS) were significantly higher Groups 1 2 than control group. There...

Summary Objective The spectrum of genetic alterations in cases hypogonadotropic hypogonadism continue to expand. However, KISS 1R mutations remain rare. aim this study was understand the molecular basis normosmic idiopathic hypogonadism. Methods Clinical characteristics, hormonal studies and analyses seven with ( nIHH ) from three unrelated consanguineous families are presented. Results One male presented absence pubertal onset required surgery for severe penoscrotal hypospadias...

Infant botulism is a rare condition caused by intestinal colonization with Clostridium botulinum.The enteric toxin causes immobility and progressive descending paralysis due to the eff ect on acetylcholine release at neuromuscular junction other cholinergic nerve terminals, particularly in gut.Herein, we report an infant infantile because of clinically entity, early diagnosis appropriate treatment recover no squeal.

To determine the oxidative stress and trace element levels in vivo patients with nutritional rachitism associated vitamin D deficiency.A total of 30 patients, 18 males 12 females, were included study. Age, sex, medical history, vital, physical examination findings each patient documented at presentation recorded. Serum calcium, phosphorus, alkaline phosphatase, parathormone, 25-OH levels, as well oxidant antioxidant system parameters studied. After being diagnosed rachitism, administered a...

Metabolic impairment in type 1 diabetes mellitus (T1DM) with poor glycemic control causes insulin resistance, non-alcoholic fatty liver disease (NAFLD), atherosclerosis, and increased carotid intima-media thickness (CIMT). Fetuin-A has a protective effect cardiovascular disorders is hepatosteatosis. We aimed to investigate the reliability of fetuin-A levels early detection diabetic complications children T1DM identify cut-off value that may show metabolic control.The study included 80...

Primary cardiac tumours are uncommon, with an estimated incidence between 0.0017% and 0.19%. Cardiac myxoma is a rare cause of cerebrovascular disease, especially in children. This case report emphasizes the importance evaluation, echocardiographic examination cases stroke peripheral embolism.

Thrombotic thrombocytopenic purpura (TTP) is characterized by disseminated thrombotic occlusions located in the microcirculation and a syndrome of microangiopathic hemolytic anemia, thrombocytopenia, fever, renal neurologic abnormalities. encountered variety clinical situations such as viral, bacterial, mycobacterial infections, autoimmune disorders, drug reactions, connective tissue disease, solid tumors. In this report, we present TTP case brucellosis because rare presentation. A...

Congenital hypothyroidism (CH) is the most common neonatal endocrine disorder and mutations in TPO gene have been reported to cause CH. Our aim this study was determine genetic basis of CH two affected individuals coming from a consanguineous family.Since usually inherited autosomal recessive manner consanguineous/multi-case families, we adopted two-stage strategy linkage studies targeted sequencing candidate genes. First, investigated potential family any known locus using microsatellite...

Cerebral venous sinus thrombosis (CVST) is an uncommon disease in childhood. In the largest study carried out so far, incidence was 0.67 case per 100 000 children year. A number of etiologies and risk factors have been far identified for CVST childhood, including head trauma, local systemic infectious diseases, malignancies, autoimmune diseases. Celiac (CD) a small intestine caused by immune response to ingested gluten. Epilepsy, bilateral occipital calcification, cerebellar ataxia,...

Although advanced diagnostic and treatment methods are available, congenital heart disease (CHD) holds an important place among the causes of death within first year age. Therefore, several prognostic factors needed for diagnosis monitoring these patients. In this study, which includes 66 CHD patients 38 healthy control children, serum cardiac troponin-I (cTnI), high-sensitivity C-reactive protein (Hs-CRP), N-terminal prohormone brain-type natriuretic peptide (NT-proBNP) levels were analyzed...

To examine the effect of 25-OH vitamin D3 on immune system in patients with nutritional rickets.Fifty-three were included our study between April 2002 and March 2004. Diagnosis rickets was based clinical, biochemical radiological examinations. Cell surface markers (CD), complement factors (C), immunoglobulin (Ig) levels determined to find out any relationship deficiency.Among causes admission hospital, fever (66%) coughing (62.2%) most frequent. Pneumonia accompanied by 47.1% cases. Plasma...

The role of immature granulocyte in the early prediction acute perforated and nonperforated appendicitis children diagnosis.Delay diagnosis surgery for AA may lead to complications associated with perforation, gangrene, intraabdominal abscess formation.Appendiceal perforation is increased morbidity mortality compared non-perforating.It difficult make a correct due nonspecificity symptoms lack specific biomarkers. [3,4]Although studies have been conducted on many markers such as white blood...

Introduction Diabetic nephropathy associated with end-stage renal disease (ESRD) is a significant public health problem due to its high morbidity and mortality. We aimed improve the estimation of proteinuria in diabetic patients potentially enhance risk stratification clinical management strategies assessment correlation neutrophil/lymphocyte ratio (NLR), low-density lipoprotein/albumin (LAR), red cell distribution width/albumin (RAR) uncontrolled diabetes patient population. Methods This...