- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Multiple Sclerosis Research Studies
- Infectious Aortic and Vascular Conditions
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Elasticity and Material Modeling
- Ocular Diseases and Behçet’s Syndrome
- Anesthesia and Pain Management
- Peripheral Neuropathies and Disorders
- Systemic Lupus Erythematosus Research
- Vascular anomalies and interventions
- Neurogenesis and neuroplasticity mechanisms
- Central Venous Catheters and Hemodialysis
- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Vascular Procedures and Complications
San Francisco VA Medical Center
2020-2021
University of California, San Francisco
2017-2021
Aortic dissection (AD) is a life-threatening event that occurs when the intimal entry tear propagates and separates inner from outer layers of aorta. Diameter, current criterion for aneurysm repair, far ideal additional evidence to optimize clinical decision would be extremely beneficial. Biomechanical investigation regional failure properties aortic tissue essential understand proactively prevent AD. We previously studied biaxial mechanical healthy human In this study, we investigated...
No single neuroimaging technique or sequence is capable of reflecting the functional deficits manifest in MS. Given interest imaging biomarkers for short- to medium-term studies, we aimed assess which metrics might best represent impairment monitoring clinical trials. complexity MS, however, it useful isolate a particular functionally relevant pathway understand relationship between and neurological function. We therefore analyzed existing data, combining multiparametric MRI OCT describe MS...
Objective: Wall stress may better predict aortic aneurysm rupture/dissection risk than diameter. A biomechanics-based assessment of ascending thoracic aneurysms (aTAA) will first require wall data from non-aneurysmal aortas to help determine thresholds for intervention. The objective this study was quantify values in serve as controls computational studies aTAA stresses. Methods: Aortic root and tissue were obtained 11 human donor hearts rejected transplantation with no history cardiac...