Stephen Ayisi Addo

ORCID: 0000-0003-0472-2281
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About
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Research Areas
  • HIV/AIDS Research and Interventions
  • HIV, Drug Use, Sexual Risk
  • Adolescent Sexual and Reproductive Health
  • Global Maternal and Child Health
  • Sex work and related issues
  • HIV-related health complications and treatments
  • HIV/AIDS Impact and Responses
  • HIV Research and Treatment
  • HIV/AIDS drug development and treatment
  • Healthcare Systems and Reforms
  • Syphilis Diagnosis and Treatment
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Poverty, Education, and Child Welfare
  • Advanced Causal Inference Techniques
  • Cervical Cancer and HPV Research
  • COVID-19 Impact on Reproduction
  • Reproductive tract infections research
  • Insect Resistance and Genetics
  • Hepatitis B Virus Studies
  • Global Health and Epidemiology
  • Child Nutrition and Water Access
  • Insurance and Financial Risk Management
  • Malaria Research and Control
  • Genital Health and Disease
  • Diabetes, Cardiovascular Risks, and Lipoproteins

Ghana Health Service
2014-2025

Korle Bu Teaching Hospital
2021-2023

Ministry of Health
2020

Ghana AIDS Commission
2020

Abstract Background For women living with HIV (WLHIV), the burden of persistent HPV infection, cervical pre-cancerous lesions and cancer have been demonstrated to be higher than among HIV-negative women. As Ghana other lower-middle-income countries (LMIC) work toward developing national programmes, it is essential that local scientific evidence provided guide policy decisions, especially for such special populations. The objective this study was determine distribution high-risk genotype...

10.1186/s13027-023-00513-y article EN cc-by Infectious Agents and Cancer 2023-05-26

Ghana has been providing HIV and AIDS services since the identification of first case in 1986 added highly active antiretroviral therapy to its comprehensive care 2003.This study aimed at assessing availability along continuum Ghana.A cross sectional was conducted among 172 (87%) total 197 ART canters Ghana. Data collected by self-administered questionnaire analysed using STATA version 13.Of health facilities surveyed, 165 (96%) were offering testing Services (HTS) during survey period. More...

10.1186/s12913-018-3485-z article EN cc-by BMC Health Services Research 2018-09-26

Ghana has a generalized HIV epidemic and efforts have been made to curb the spread reverse its effects on general population. In wake of COVID-19 pandemic, health system was unsettled antiretroviral therapy (ART) care impacted in diverse ways. The study sought explore ART service provision from perspectives healthcare workers.An exploratory-descriptive qualitative approach employed this study. Using maximum variation sampling method, fifteen workers; nurses, data managers pharmacists were...

10.1186/s12913-021-07330-2 article EN cc-by BMC Health Services Research 2021-12-01

Abstract Background and Aims An important but much less researched burden of human immunodeficiency virus (HIV) in Sub‐Saharan Africa includes the associated mental health outcomes living with virus. This study aimed to estimate prevalence depression, anxiety, stress, describe some socio‐demographic associations among people HIV (PLHIV) Ghana. Methods A cross‐sectional was conducted at Cape Coast Teaching Hospital, Simple random sampling used recruit 395 PLHIV who access HIV‐related services...

10.1002/hsr2.754 article EN Health Science Reports 2022-08-08

Abstract Background Dolutegravir (DTG), a new antiretroviral drug, is being integrated into regimens for people with human immunodeficiency virus (PWH) in Ghana. There little evidence of the effect DTG on blood pressure (BP) levels sub-Saharan Africa, especially West Africa. Our aim was to assess incidence and predictors hypertension (HTN) among PWH initiated DTG-based regimen Methods An observational multicenter longitudinal study conducted Ghana from 2020 2022. BPs nonhypertensive patients...

10.1093/ofid/ofae061 article EN cc-by-nc-nd Open Forum Infectious Diseases 2024-02-05

Abstract Background Under the auspices of Ministry Health (MoH) and National AIDS/STI Control Programme (NACP), Ghana piloted an HIV Self-Testing (HIVST) project in 2023. The implementation took place 50 high burden districts it was spearheaded by AIDS Network (GHANET), a grassroots civil society organization (CSO) with membership across country. This paper examines strategies outcomes which sponsored Global Fund currently being expanded as part Grant Cycle Seven (GC7) from 2024 to 2026....

10.1093/ofid/ofae631.675 article EN cc-by Open Forum Infectious Diseases 2025-01-29

Introduction Ghana is working towards achieving the 95-95-95 targets for its HIV response. One challenge has been low linkage to care rates, possibly due high rates of retesting among people living with who are already aware their status. This leads an overestimation first 95 and a subsequent underestimation second 95. study aimed measure prevalence PLHIV in status explore reasons retesting. Methods was facility-based cross-sectional conducted three ecological zones Ghana. A total 11,145...

10.1371/journal.pone.0316915 article EN cc-by PLoS ONE 2025-02-21

Objectives The use of antiretroviral therapy has been linked to the development some components metabolic syndrome (MetS), specifically glucose intolerance, weight gain and defective lipid metabolism. This study determined relationship between dolutegravir (DTG) MetS in a cohort persons living with HIV (PWH) initiating DTG-based regimen Ghana. Design A 2-year observational prospective was conducted from September 2020 August 2022. Setting Five high-burden facilities providing services at...

10.1136/bmjopen-2024-097340 article EN cc-by-nc-nd BMJ Open 2025-05-01

Introduction People living with HIV/AIDS (PLWHA) have complex physical, psychological, social and spiritual needs following diagnosis poorer health-related quality of life than the general population. Holistic assessment care delivery incorporating person-centred principles is required to address these needs. This protocol describes a cluster randomised controlled trial (cRCT) process evaluation evaluate effectiveness extra community-based enhanced intervention (ExtraCECI) improve outcomes...

10.1136/bmjopen-2025-102692 article EN cc-by-nc-nd BMJ Open 2025-05-01

Despite global scale up of interventions for Preventing Mother to child HIV Transmissions (PMTCT), there still remain high pediatric infections, which result from unequal access in resource-constrained settings. Sub-Saharan Africa alone contributes more than 90 % Mother-to-Child Transmission (MTCT) burden. As part efforts address this, African countries (including Ghana) disproportionately contributing MTCT burden were earmarked 2009 rapid PMTCT scale-up within their primary care system...

10.1186/s12939-016-0300-5 article EN cc-by International Journal for Equity in Health 2016-01-13

Objective To explore how the COVID-19 pandemic affected access to antiretroviral therapy (ART) services from perspective of persons living with HIV (PLWH). Design The study adopted an exploratory-descriptive qualitative design that used in-depth interviews as technique for data collection. Data analysis was done using conceptual content analysis, following traditions Elo and Kyngäs on deductive Hsieh inductive analysis. Setting ART clinic, Cape Coast Teaching Hospital, Ghana. Participants...

10.1136/bmjopen-2021-056386 article EN cc-by-nc BMJ Open 2022-05-01

The need to study the outcome of Antiretroviral Therapy (ART) among Human Immunodeficiency Virus (HIV) infected individuals in Ghana, a sub-Saharan African country crucial era "Treat All" policy. aim this was analyze selected determinants immunological and virological response ART HIV tertiary facility Cape Coast, Ghana. An analytical cross sectional with retrospective component conducted Coast Teaching Hospital (CCTH), Central Region. Clients aged 18 years above attending Clinics for who...

10.1186/s12879-018-3142-5 article EN cc-by BMC Infectious Diseases 2018-05-21

Background: HIV self-testing (HIVST) has the potential to greatly increase testing uptake, particularly among key populations (KPs) at higher risk for HIV. Studies have shown high acceptability and feasibility of HIVST various target globally. However, less is known about perspectives policymakers, who are critical success implementation. Their views on barriers introduction scale-up understand in order become part national guidelines. We sought policymakers' challenges facilitators client...

10.3389/fpubh.2021.694836 article EN cc-by Frontiers in Public Health 2021-09-21

Abstract Background Key populations (KPs) such as female sex workers (FSWs), men who have with (MSM), people inject drugs (PWID), and their partners contribute more than a quarter (27.5%) of new HIV infection in Ghana. Oral pre-exposure prophylaxis (PrEP) can substantially reduce acquisition among this group. While the available research indicates KPs willingness to take PrEP Ghana, little is known about position policymakers healthcare providers on introduction for KPs. Methods Qualitative...

10.1186/s12889-023-15871-w article EN cc-by BMC Public Health 2023-06-05

The Joint United Nations Programme on HIV/AIDS (UNAIDS) goal to end the acquired immunodeficiency syndrome (AIDS) epidemic as a public health threat by 2030 emphasises importance of leaving no one behind. To determine progress towards elimination in Ghana, an in-depth understanding human virus (HIV) care from perspective vulnerable populations such persons living with HIV incarceration is necessary. This study aims explore experiences incarcerated individuals (ILHIV) and antiretroviral...

10.1108/ijoph-06-2023-0031 article EN cc-by International Journal of Prison Health 2024-01-17

Few studies have reported hyperglycemia and diabetic ketoacidosis in patients on dolutegravir (DTG) treatment. This study determined the effect of DTG fasting blood glucose levels a cohort persons living with HIV (PLHIV) Ghana initiating regimens. A two-year observational longitudinal conducted from 12th October 2020 to 31st December 2022. Fasting was measured at baseline, 12, 24, 36 72 weeks for after 12 h overnight fast. The Kaplan-Meier estimator used estimate risk developing type 2...

10.1186/s41043-024-00695-0 article EN cc-by-nc-nd Journal of Health Population and Nutrition 2024-11-29

Previous studies have suggested high Immunodeficiency Virus (HIV) and hepatitis B virus (HBV) prevalence in prisons Ghana. However, this study was part of a nationally representative bio-behavioural survey determined the HIV HBV among prison inmates identified factors associated with these infections. Both biomedical behavioural data were collected from total 2,443 19 stations during 2013 Ghana; 12 male 7 female selected across country. The national screening algorithm used for testing while...

10.1371/journal.pone.0293009 article EN cc-by PLoS ONE 2023-11-03

Several health interventions have been put in place to improve outcomes of people living with HIV/AIDS (PLHIV) Ghana. We evaluated the impact Antiretroviral Therapy (ART) on all-cause mortality Ghana using matching procedures. This was a retrospective cohort study 12,881 patients initiated ART at 40 sentinel sites and 199 treatment centers between 2013 2016 countrywide. Patients were included if they had date initiation outcome recorded. Mahalanobis distant metric within propensity score...

10.1371/journal.pone.0203461 article EN cc-by PLoS ONE 2018-09-07

Background Apart from HIV acquisition, men who have sex with are at a higher risk of sexually transmitted infections, especially syphilis. Although the intersection between syphilis and poses formidable challenge among key populations known to be vulnerable many health threats, there is little about infection MSM living in Ghana. This study seeks investigate burden address existing knowledge gap by exploring behavioral, healthcare access, structural factors influencing within HIV-positive...

10.1371/journal.pone.0310909 article EN cc-by PLoS ONE 2024-09-25

Objective: The study assessed the dominant risk factors associated with risky sexual behavior (RSB) and further quantify its influence on HIV infection among Ghanaians aged 15–49 years using Ghana demographic Health Survey (GDHS). Methods: A cross-sectional two rounds of GDHS (2003 = 7448 2014 10169). RSB were outcomes. employed analysis to rank important RSB. Meta-analysis was conducted obtain heterogeneity in prevalence by Logistic Inverse Probability Weighting (LIPW) model estimate...

10.1177/26318318241276989 article EN cc-by-nc Journal of Psychosexual Health 2024-07-01
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