A5015596573- Ultrasound and Cavitation Phenomena
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Ultrasound and Hyperthermia Applications
- EEG and Brain-Computer Interfaces
- Neuroscience and Neural Engineering
- Photoacoustic and Ultrasonic Imaging
- Nonlinear Dynamics and Pattern Formation
- Fluid Dynamics and Mixing
- Epilepsy research and treatment
- Advanced Chemical Sensor Technologies
- Neurological disorders and treatments
- Ultrasonics and Acoustic Wave Propagation
- Parkinson's Disease Mechanisms and Treatments
- Innovative Microfluidic and Catalytic Techniques Innovation
- Computer Graphics and Visualization Techniques
- Vestibular and auditory disorders
- Underwater Acoustics Research
- Particle Dynamics in Fluid Flows
- Tactile and Sensory Interactions
- Advanced Image Processing Techniques
- Photoreceptor and optogenetics research
- Sleep and related disorders
- Advanced Neuroimaging Techniques and Applications
- Ocular Surface and Contact Lens
Consejo Nacional de Investigaciones Científicas y Técnicas
2013-2025
Bariloche Atomic Centre
2012-2025
Inserm
2023-2025
Aix-Marseille Université
2023-2024
Institut de Neurosciences des Systèmes
2023-2024
Comisión de Investigaciones Científicas
2024
Balseiro Institute
2011-2023
Universidad Nacional de Cuyo
2019-2023
Comisión Nacional de Energía Atómica
2017-2023
Abstract Temporal Interference (TI) is an emerging method to non-invasively stimulate deep brain structures. This innovative technique increasingly recognized for its potential applications in the treatment of various neurological disorders, including epilepsy, depression, and Alzheimer’s disease. However, several drawbacks TI exist that we aim improve upon. To begin, applied electric field target not much higher than what non-invasive transcranial alternating current stimulation (TACS)...
We studied the rate dynamics of interictal events occurring over fast-ultradian time scales, as commonly examined in clinics to guide surgical planning epilepsy.Stereo-electroencephalography (SEEG) traces 35 patients with good outcome (Engel I) were analyzed. For this we developed a general data mining method aimed at clustering plethora transient waveform shapes including epileptiform discharges (IEDs) and assessed temporal fluctuations capability mapping epileptogenic zone (EZ) each type...
Deep brain stimulation (DBS) has become a widely used technique for treating advanced stages of neurological and psychiatric illness. In the case motor disorders related to basal ganglia (BG) dysfunction, several mechanisms action DBS therapy have been identified which might be involved simultaneously or in sequence. However, identification common key mechanism underlying clinical relevant configurations remained elusive due inherent complexity interaction between electrical neural tissue,...
In this study we report several experimental and numerical results on the influence of static pressure (${P}_{0}$) over main parameters in single bubble sonoluminescence (SBSL), using a sulfuric acid aqueous solution (SA) with low concentrations argon gas dissolved. Bifrequency driving was used experiments to enhance spatial stability bubbles. The were compared simulations provided by code that models radial dynamics showed an increase system shifts Bjerknes instability threshold, allowing...
Single-bubble sonoluminescence (SBSL) was explored under a variety of multifrequency excitations. In particular, biharmonic excitation used to produce SBSL for unprecedented low dissolved noble gas concentrations in sulfuric acid solution. Reducing the amount makes it possible reach higher acoustic pressures on SL bubble, which otherwise are not attainable because Bjerknes instability. By using excitation, we were able experimentally trap and spatially stabilize bubbles xenon pressure...
Particle image velocimetry (PIV) allows measuring distributed flow velocity fields. It is well established as an experimental tool in modern fluid dynamics research, being applied to liquid, gases and multiphase flows. Images of tracer particles are processed by means a statistical strategy, which makes its real-time implementation difficult achieve. In this paper, we describe the design embedded architecture for PIV based on FPGA technology. The proposed scheme has allowed us exploit...
The acoustic field in the liquid within a spherical solid shell is calculated. proposed model takes into account Stoke’s wave equation viscous fluid, membrane theory to describe motion and energy loss through external couplings of system. A point source at resonator center included reproduce emission sonoluminescence bubble. Particular calculations resulting are performed for liquids interest single bubble sonoluminescence. reveals that case radially symmetric modes low frequency, quality...
An experimental study of the extinction threshold single bubble sonoluminescence in an air-water system is presented. Different runs from 5% to 100% air concentrations were performed at room pressure and temperature. The intensity (SL) time collapse (tc) with respect driving measured while acoustic was linearly increased onset SL until extinction. data compared theoretical predictions for shape position instability thresholds. It found that determined by different mechanisms depending on...
Cross-frequency coupling (CFC) refers to the nonlinear interaction between oscillations in different frequency bands, and it is a rather ubiquitous phenomenon that has been observed variety of physical biophysical systems. In particular, phase slow amplitude fast oscillations, referred as phase-amplitude (PAC), intensively explored brain activity recorded from animals humans. However, interpretation these CFC patterns remains challenging since harmonic spectral correlations characterizing...
An integrated multi-harmonic control system based on field programmable gate array (FPGA) technology is developed in this article. The was designed to generate a controlled excitation for non linear phenomenon: single bubble sonoluminescence (SBSL). target our experiment constituted by set of senoidal signals, the fundamental frequency and several harmonic frequencies. FPGA device allowed customized implementation successfully all design requests board. On line over largest number harmonics...
We study, numerically and experimentally, three different methods to suppress the trajectories of strongly collapsing sonoluminescent bubbles in a highly viscous sulfuric acid solution. A new numerical scheme based on window method is proposed account for history force acting spherical bubble with variable radius. could quantify force, which not negligible comparison primary Bjerknes this type problem, results are agreement classical trapping threshold analysis. Moreover, present...
Abstract Objective Brain oscillations, broadband 1 /f activity and neuronal avalanches (NA) are valuable conceptualizations extensively used to interpret brain data, yet, these perspectives have mainly progressed in parallel with no current consensus on a rationale linking them. This study aims reconcile viewpoints using source-reconstructed MEG data obtained healthy humans during eyes-closed resting state. Methods We analyzed NA from 47 subjects. For this, we introduced custom measures...
Background: Temporal Interference (TI) is an emerging method to non-invasively stimulate deep brain structures, where combinations of electric fields at different high frequencies (in kHz) are used as carrier signals, typically sinusoidal, resulting in spatially steerable amplitude modulated (AM) signals. The difference-frequency between the two high-frequency carriers, called envelope frequency (Δf), has been shown modulate neuronal activity.Hypothesis: While this innovative technique holds...
We developed a technique that detects superficial ocular pathologies based on the measurement of electrical impedance spectra. The sensor used is small microelectrode made platinum insulated from cylindrical counterelectrode built surgical stainless steel. has shape truncated cone acrylic with dimensions identical to standard Goldman prism. applied normal and pathological subject eyes constant force provided by commercial tonometer. circuit closed through lacrimal layer epithelial...
The Cross-Frequency Coupling (CFC) characterizes the correlation between phase/amplitude of a low-frequency band with those high-frequency within or across time series. CFC phenomenon has been observed in variety systems: earth seismic waves, stock market fluctuations, pulsatile hormone secretions and scale-free activity human brain. In this work, experiments were conducted using liquid-filled spherical chamber arranged an experimental setup tailored for characterizing acoustic field...
The dynamic-clamp electrophysiological technique allows the mimicking of electrical effects ion channels embedded into membrane an intracellularly recorded cell. Dynamic-clamp relies on establishing a loop between injected current and potential. In this work, real-time system was implemented Field Programmable Gate Array (FPGA). proposed concurrent controlling activation several channels. architecture instrument developed is based two main modules: state machine (as logic arbiter) with ADC...
Abstract Background Cross-frequency coupling (CFC) refers to the non linear interaction between oscillations in different frequency bands, and it is a rather ubiquitous phenomenon that has been observed variety of physical biophysical systems. In particular, phase slow amplitude fast oscillations, referred as phase-amplitude (PAC), intensively explored brain activity recorded from animals humans. However, interpretation these CFC patterns remains challenging since harmonic spectral...
Sleep disorders can be a negative factor both for learning as the mental and physical development of adolescents. It has been shown that, in many populations, adolescents tend to have poor sleep quality, very late chronotype. Furthermore, these features peak at adolescence, sense that adults better an earlier But what happens when we consider population where already quality chronotype? We conducted two non-clinical studies city Bariloche, Argentina aimed measuring chronotype, social jet...
Abstract Objective We studied the rate dynamics of interictal events occurring over fast-ultradian time scales, as commonly examined in clinics to guide surgical planning epilepsy. Methods Stereoelectroencephalography (SEEG) traces 35 patients with good outcome (Engel I) were analyzed. For this, we developed a general data mining method aimed at clustering plethora transient waveform shapes including epileptiform discharges (IEDs), and assessed temporal fluctuations capability map...