- Aquaculture disease management and microbiota
- Invertebrate Immune Response Mechanisms
- Coral and Marine Ecosystems Studies
- Marine Bivalve and Aquaculture Studies
- Hydrocarbon exploration and reservoir analysis
- Aquaculture Nutrition and Growth
- Physiological and biochemical adaptations
- Neuropeptides and Animal Physiology
- Ocean Acidification Effects and Responses
- Antimicrobial Peptides and Activities
- Neuroendocrine regulation and behavior
- Microplastics and Plastic Pollution
- Marine and coastal plant biology
- Marine Biology and Environmental Chemistry
- Environmental Toxicology and Ecotoxicology
- Marine Sponges and Natural Products
- Echinoderm biology and ecology
- Stress Responses and Cortisol
- Marine and coastal ecosystems
- Paleontology and Stratigraphy of Fossils
- Methane Hydrates and Related Phenomena
- Geological Studies and Exploration
- Neurobiology and Insect Physiology Research
- Microbial Community Ecology and Physiology
- Nitric Oxide and Endothelin Effects
Hainan University
2016-2025
GE Vernova (United States)
2024
China Geological Survey
2018-2023
University of Connecticut
2018-2021
Ministry of Natural Resources
2020
Chinese Academy of Sciences
2010-2019
Institute of Oceanology
2010-2019
Dalian Ocean University
2019
University of Chinese Academy of Sciences
2009-2012
Luye Pharma (Switzerland)
2011
Background MicroRNAs (miRNAs) represent a class of small ncRNAs that repress gene expression on the post-transcriptional level by degradation or translation inhibition target mRNA. Methodology Three RNA libraries from oyster haemocytes were sequenced Illumina platform to investigate latent immunomodulation miRNAs after bacteria challenge and heat stress. Totally, 10,498,663, 8,588,606 9,679,663 high-quality reads obtained in control, bacteria+heat library, respectively, which 199 including...
Background The C1q domain containing (C1qDC) proteins refer to a family of all that contain the globular (gC1q) domain, and participate in series immune responses depending on their gC1q domains bind variety self non-self binding ligands. Methodology In present study, mRNA expression patterns, localization, activities C1qDC protein from scallop Chlamys farreri (CfC1qDC) were investigated understand its possible functions innate immunity. relative levels CfC1qDC hemocytes significantly...
Abstract The neuroendocrine-immune (NEI) regulatory network is a complex system, which plays an indispensable role in the immunity of host. In present study, bioinformatical analysis transcriptomic data from oyster Crassostrea gigas and further biological validation revealed that TNF (CgTNF-1 CGI_10018786) could activate transcription factors NF-κB HSF (heat shock factor) through MAPK signaling pathway, then regulate apoptosis, redox reaction, neuro-regulation protein folding haemocytes....
Abstract Marine bivalves secrete calcified shells to protect their soft bodies from predation and damages, which is of great importance for survival, the safety coastal ecosystem. In recent years, larval shell formation marine has been severely affected by ocean acidification (OA), previous study indicated that OA might affect such process disrupting endogenous energy metabolism. Developmental stages trochophore D-shape larvae are extremely important initial in oyster since a was formed...
The neuroendocrine-immune (NEI) regulatory network is a complex system, which plays an indispensable role in the immunity of host. In this study, neuroendocrine immunomodulatory axis (NIA)-like pathway mediated by nervous system and haemocytes was characterized oyster Crassostrea gigas Once invaded pathogen recognized host, would temporally release neurotransmitters to modulate immune response. Instead acting passively, were able mediate neuronal immunomodulation promptly controlling...