A5058722523- Stress Responses and Cortisol
- Heart Rate Variability and Autonomic Control
- Mental Health Research Topics
- Cardiac Health and Mental Health
- Neurotransmitter Receptor Influence on Behavior
- Primate Behavior and Ecology
- Blood Pressure and Hypertension Studies
- Neuroendocrine regulation and behavior
- Behavioral Health and Interventions
- Functional Brain Connectivity Studies
- Psychological Well-being and Life Satisfaction
- Tryptophan and brain disorders
- Health disparities and outcomes
- Child and Adolescent Psychosocial and Emotional Development
- Cognitive Abilities and Testing
- Neural and Behavioral Psychology Studies
- Personality Traits and Psychology
- Lipoproteins and Cardiovascular Health
- Fatty Acid Research and Health
- Cardiovascular Health and Disease Prevention
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Sleep and related disorders
- Birth, Development, and Health
- Personality Disorders and Psychopathology
- Receptor Mechanisms and Signaling
University of Pittsburgh
2016-2025
Corning (United States)
2023
ORCID
2023
Weatherford College
2023
Utrecht University
2022
Carnegie Mellon University
1991-2020
Center for the Neural Basis of Cognition
2010-2020
RAND Corporation
2014
Icahn School of Medicine at Mount Sinai
2007-2014
Duke Medical Center
2012
Although controversy continues, the preponderance of evidence indicates that estrogen replacement therapy favorably influences risk coronary heart disease in postmenopausal women. It remains uncertain how this effect is mediated and whether cyclic addition a progestin may influence adversely an estrogen-related cardioprotective effect. We investigated sex hormone on diet-induced artery atherosclerosis estrogen-deficient (ovariectomized) adult female cynomolgus monkeys. Monkeys were assigned...
Discounting future outcomes as a function of their deferred availability underlies much human decision making. Discounting, or preference for immediate over delayed rewards larger value, is often associated with impulsivity and risk factor addictive disorders such pathological gambling, cigarette smoking, drug alcohol abuse. The ventral striatum (VS) involved in mediating behavioral responses physiological states reward, dysregulation the VS contributes to addiction, perhaps by affecting...
Study objective:Short and long sleep duration have been linked to various risk factors for cardiovascular disease. In the present study, we evaluated relationship between presence of metabolic syndrome, which is a cluster physiologically interrelated cardiometabolic
Background We examined the relation between cardiovascular reactivity (the response of system to psychological stress) and severity progression carotid atherosclerosis. Methods Using duplex ultrasonography, we measured change in area all detectable plaques extracranial arteries during 2 years. Cardiovascular was assessed by measuring changes hemodynamics a frustrating cognitive task Stroop Color Word Interference Task). Established risk factors for atherosclerosis were interviewing patients,...
In this study we investigated the effects of nonevaluative social interaction on cardiovascular response to psychological challenge. Thirty-nine college-age females appeared accompanied ("Friend" condition) or unaccompanied ("Alone" an experimental laboratory. Friend condition, partners were present while subject participated in two laboratory tasks, and partners' evaluation potential was minimized by design. Subjects condition showed reduced heart rate reactivity both relative Alone group,...
Shift work, which imposes a habitual disruption in the circadian system, has been linked to increased incidence of cardiometabolic diseases, and acute misalignment alters various metabolic processes. However, it remains unclear whether day-to-day dysregulation contributes these risks beyond poor sleep other behavioral characteristics.
Neuroimaging has identified many correlates of emotion but not yet yielded brain representations predictive the intensity emotional experiences in individuals. We used machine learning to identify a sensitive and specific signature responses aversive images. This predicted negative individual participants cross validation (n =121) test = 61) samples (high-low 93.5% accuracy). It was unresponsive physical pain (emotion-pain 92% discriminative accuracy), demonstrating that it is representation...
To determine whether a simple, structured self-report of overall sleep quality is associated with the presence metabolic syndrome and its component risk factors. An observational, cross-sectional study comparing global scores on Pittsburgh Sleep Quality Index concurrently collected measures components or absence syndrome. The criterion American Heart Association/National Heart, Blood, Lung Institute was adopted. University laboratory. Two hundred ten volunteers mean age 46 years (57% men)...
The purpose of this experiment was to examine the effects social environment and status on coronary artery aortic atherosclerosis in adult male cynomolgus monkeys (Macaca fascicularis). Thirty experimental animals were assigned six groups five members each, all fed a moderately atherogenic diet (43% calories as fat, 0.34 mg cholesterol/Cal) for 22 months. Group memberships changed periodically among 15 (unstable condition) remained fixed throughout remaining (stable condition). Within each...