A5073572754- Plant Pathogens and Fungal Diseases
- Diatoms and Algae Research
- Mycorrhizal Fungi and Plant Interactions
- Lichen and fungal ecology
- Plant-Microbe Interactions and Immunity
- Plant Disease Resistance and Genetics
- Plant Water Relations and Carbon Dynamics
- Plant Molecular Biology Research
- Genomics and Phylogenetic Studies
- Algal biology and biofuel production
- Monoclonal and Polyclonal Antibodies Research
- Oil Palm Production and Sustainability
- Plant Pathogenic Bacteria Studies
- Plant Stress Responses and Tolerance
- Blood properties and coagulation
- Erythrocyte Function and Pathophysiology
- Plant biochemistry and biosynthesis
- Mesenchymal stem cell research
- Intestinal Malrotation and Obstruction Disorders
- Single-cell and spatial transcriptomics
- Epigenetics and DNA Methylation
- Genetic and phenotypic traits in livestock
- Plant Reproductive Biology
- Ion Transport and Channel Regulation
- Tree Root and Stability Studies
Genetic Improvement and Adaptation of Mediterranean and Tropical Plants
2018-2025
Agropolis International
2018-2025
Centre de Coopération Internationale en Recherche Agronomique pour le Développement
2020-2025
Max Planck Institute for Evolutionary Anthropology
2024
Gilead Sciences (United States)
2019-2024
Inter-American Development Bank
2024
Hospital Sant Joan de Déu Barcelona
2023
Université de Montpellier
2020-2023
Institut de Recerca Sant Joan de Déu
2023
Jimma University
2022
DNA methylation is a heritable epigenetic mark that controls gene expression, responsive to environmental stresses, and, in plants, may also play role heterosis. To determine the degree which inherited rice, and how it both influences affected by transcription, we performed genome-wide measurements of these patterns through an integrative analysis bisulfite-sequencing, RNA-sequencing, siRNA-sequencing data two inbred parents Nipponbare (NPB) indica (93–11) varieties rice their hybrid...
Significance The growing human population generates increasing demand for food and energy. Microalgae are a promising source of sustainable bioproducts whose production may not exacerbate worsening environmental problems. green alga Chromochloris zofingiensis has potential as biofuel feedstock high-value nutraceutical molecules, including the carotenoid astaxanthin. We present high-quality, chromosome-level assembly genome by using hybrid sequencing approach with independent validation...
Lichens, encompassing 20,000 known species, are symbioses between specialized fungi (mycobionts), mostly ascomycetes, and unicellular green algae or cyanobacteria (photobionts). Here we describe the first parallel genomic analysis of mycobiont Cladonia grayi its algal photobiont Asterochloris glomerata. We focus on genes/predicted proteins potential symbiotic significance, sought by surveying differentially activated during early stages interaction in coculture, expanded contracted protein...
A novel category of major intrinsic proteins which share weak similarities with previously identified aquaporin subfamilies was recently in land plants, and named X (for unrecognized) (XIPs). Because XIPs are still ranked as uncharacterized proteins, their further molecular characterization is required. Herein, a systematic fine-scale analysis XIP sequences found flowering plant databases revealed that at least five groups. The phylogenetic relationship these groups the organization...
Corynespora cassiicola is an Ascomycetes fungus with a broad host range and diverse life styles. Mostly known as necrotrophic plant pathogen, it has also been associated rare cases of human infection. In the rubber tree, this causes leaf fall (CLF) disease, which increasingly affects natural production in Asia Africa. It found endophyte South American plantations where no CLF outbreak yet occurred. The C. species genetically highly diverse, but clear relationship evidenced between...
Abstract Inflammatory signals arising from the microenvironment have emerged as critical regulators of hematopoietic stem cell (HSC) function during diverse processes including embryonic development, infectious diseases, and myelosuppressive injuries caused by irradiation chemotherapy. However, contributions cellular subsets within that elicit niche-driven inflammation remain poorly understood. Here, we identify endothelial cells a crucial component in driving bone marrow (BM) HSC...
The cell type composition of heterogeneous tissue samples can be a critical variable in both clinical and laboratory settings. However, current experimental methods quantification (e.g., flow cytometry) are costly, time consuming have potential to introduce bias. Computational approaches that use expression data infer abundance offer an alternative solution. While these gained popularity, most fail produce accurate predictions for the full range platforms currently used by researchers or...
We investigated how an extremely transposon element (TE)-rich organism such as the plant-symbiotic ascomycete truffle Tuber melanosporum exploits DNA methylation to cope with more than 45,000 repeated elements that populate its genome.
Microalgae hold promise for yielding a biofuel feedstock that is sustainable, carbon-neutral, distributed, and only minimally disruptive the production of food feed by traditional agriculture. Amongst oleaginous eukaryotic algae, B race Botryococcus braunii unique in it produces large amounts liquid hydrocarbons terpenoid origin. These are comparable to fossil crude oil, sequestered outside cells communal extracellular polymeric matrix material. Biosynthetic engineering bio-crude requires...
Molecular signatures are collections of genes characteristic a particular cell type, tissue, disease, or perturbation. Signatures can also be used to interpret expression profiles generated from heterogeneous samples. Large gene have been previously developed and catalogued in the MSigDB database. In addition, several consortia large-scale projects systematically profiled broad purified primary cells, molecular perturbations types, tissues specific diseases, specificity breadth these...
Abstract Understanding the response of leaf hydraulic conductance (Kleaf) to light is a challenge in elucidating plant–water relationships. Recent data have shown that effect on Kleaf not systematically related aquaporin regulation, leading conflicting conclusions. Here we investigated relationship between light, Kleaf, and transcript levels five tree species (Juglans regia L., Fagus sylvatica Quercus robur Salix alba L. Populus tremula L.) grown same environmental conditions, but differing...
To help understand leaf hydraulic conductance (Kleaf) modulation under high irradiance, well-watered poplars (Populus trichocarpa Torr. & Gray ex Hook and Populus nigra L.) were studied diurnally at molecular ecophysiological scales. Transcriptional translational modulations of plasma membrane intrinsic protein (PIP) aquaporins evaluated in samples during diurnal time courses. Among the 15 poplar PIP genes, a subset two PIP1s seven PIP2s are precociously induced within first hour photoperiod...
Abstract Background Quality traits are essential determinants of consumer preferences. Dioscorea alata (Greater Yam), is a starchy tuber crop in tropical regions. However, comprehensive understanding the genetic basis underlying yam quality remains elusive. To address this knowledge gap, we employed population genomics and candidate gene association approaches to unravel factors influencing attributes boiled yam. Methods Results Comparative analysis 45 plant species revealed numerous novel...
Background and Aims: Apoptosis Signal–regulating Kinase 1 (ASK1) is activated by various pathological stimuli induces cell apoptosis through downstream p38 activation. We studied the effect of pharmacological ASK1 inhibition on cirrhosis its sequelae using comprehensive preclinical in vivo vitro systems. Approach Results: Short-term (4–6 wk) long-term (24–44 small molecule GS-444217 was tested thioacetamide-induced BALB/c. Mdr2−/− murine models HCC, primary hepatocyte death assays. therapy...
Hevea brasiliensis, a natural rubber producing species, is widely cultivated due to its high yield potential. Natural synthesised in the particles of laticifers. Latex diagnosis (LD) was established characterise physiological state laticiferous system by measuring parameters, i.e., sucrose, inorganic phosphorous (Pi), thiols and total solid content (TSC). Rubber clones are often classified three groups quick starters, medium starters slow starters. To better understand genetic bases latex...