A5015636100- Cerebrospinal fluid and hydrocephalus
- Functional Brain Connectivity Studies
- Neuroscience of respiration and sleep
- Action Observation and Synchronization
- EEG and Brain-Computer Interfaces
- Traumatic Brain Injury and Neurovascular Disturbances
- Neural dynamics and brain function
- Ion Transport and Channel Regulation
- Opinion Dynamics and Social Influence
- Evolutionary Game Theory and Cooperation
- Fetal and Pediatric Neurological Disorders
- Spinal Dysraphism and Malformations
- Neonatal and fetal brain pathology
- Child and Animal Learning Development
- Neuroscience and Neural Engineering
- Hemispheric Asymmetry in Neuroscience
- Neurogenesis and neuroplasticity mechanisms
- Neurological disorders and treatments
- Embodied and Extended Cognition
Technical University of Denmark
2022-2025
University of Copenhagen
2018-2024
Amsterdam Neuroscience
2022
Vrije Universiteit Amsterdam
2022
Translational Therapeutics (United States)
2018
Cisterna magna cannulation (CMc) is a straightforward procedure that enables direct access to the cerebrospinal fluid (CSF) without operative damage skull or brain parenchyma. In anesthetized rodents, exposure of dura mater by blunt dissection neck muscles allows insertion cannula into cisterna (CM). The cannula, composed either fine beveled needle borosilicate capillary, attached via polyethylene (PE) tube syringe. Using syringe pump, molecules can then be injected at controlled rates...
The neural mechanisms underlying real-time social interaction remain poorly understood. While hyperscanning has emerged as a popular method to better understand inter-brain mechanisms, methods underdeveloped, and primarily focused on synchronization (IBS). We developed novel approach employing two-brain EEG microstates, investigate during symmetric asymmetric interactive tasks. Microstates are quasi-stable configurations of brain activity that have been proposed represent basic building...
Cisterna magna cannulation (CMc) is a straightforward procedure that enables direct access to the cerebrospinal fluid (CSF) without operative damage skull or brain parenchyma. In anesthetized rodents, exposure of dura mater by blunt dissection neck muscles allows insertion cannula into cisterna (CM). The cannula, composed either fine beveled needle borosilicate capillary, attached via polyethylene (PE) tube syringe. Using syringe pump, molecules can then be injected at controlled rates...
The classical view of cerebrospinal fluid (CSF) production posits the choroid plexus as its major source. Although previous studies indicate that part CSF occurs in subarachnoid space (SAS), mechanisms underlying extra-choroidal remain elusive. We here investigated distributions aquaporin 1 (AQP1) and Na+/K+/2Cl- cotransporter (NKCC1), key proteins for choroidal production, adult rodent brain spinal cord.We have accessed AQP1 distribution intact using uDISCO tissue clearing technique by...
Background Impaired glymphatic clearance of cerebral metabolic products and fluids contribute to traumatic ischemic brain edema neurodegeneration in preclinical models. Glymphatic perivascular cerebrospinal fluid flow varies between anesthetics possibly due changes vasomotor tone thereby the dynamics periarterial (CSF)–containing space. To better understand influence carbon dioxide levels on CSF dynamics, this study examined effect size modulation distribution by changing blood anesthetic...
Objective. Post-traumatic stress disorder (PTSD) is highly heterogeneous, and identification of quantifiable biomarkers that could pave the way for targeted treatment remains a challenge. Most previous electroencephalography (EEG) studies on PTSD have been limited to specific handpicked features, their findings variable inconsistent. Therefore, disentangle role promising EEG biomarkers, we developed machine learning framework investigate wide range commonly used in order identify which...
There is broad interest in discovering quantifiable physiological biomarkers for psychiatric disorders to aid diagnostic assessment. However, finding autism spectrum disorder (ASD) has proven particularly difficult, partly due high heterogeneity. Here, we recorded five minutes eyes-closed rest electroencephalography (EEG) from 186 adults (51% with ASD and 49% without ASD) investigated the potential of EEG classify using three conventional machine learning models two-layer cross-validation....
Joint action and interpersonal coordination between individuals are integral parts of daily life, various behavioral tasks have been designed to study their emergence maintenance. One example is the mirror-game paradigm, which examines dynamics two people improvising motion together. However, underlying neural mechanisms remain poorly understood, inter-brain methods underdeveloped. Previously, we reported unique individual signatures performing actions when observed by others using a...
Verga, Kotz, and Ravignani’s paper on “The evolution of social timing” [1] provides an elegant proposal into how sociality timing are interconnected ubiquitous in human nonhuman animal interactions, proposes a framework to investigate the why it is so fundamental animals. The authors outline some key mechanisms that support timing, such as interpersonal synchronization mutual adaptation, but do not go depth with respect fine-grained temporal properties underlying individual signals, which...