A5081664669- Immune Response and Inflammation
- Adipokines, Inflammation, and Metabolic Diseases
- Exercise and Physiological Responses
- Stress Responses and Cortisol
- Muscle metabolism and nutrition
- Bioactive Compounds and Antitumor Agents
- Veterinary Equine Medical Research
- Animal health and immunology
- Antimicrobial Peptides and Activities
- Veterinary medicine and infectious diseases
- Vitamin C and Antioxidants Research
- Essential Oils and Antimicrobial Activity
- Veterinary Pharmacology and Anesthesia
- Thermoregulation and physiological responses
- Animal Nutrition and Physiology
- Anesthesia and Pain Management
- Adrenal Hormones and Disorders
- Orthopedic Infections and Treatments
- Free Radicals and Antioxidants
- Dermatology and Skin Diseases
- Trace Elements in Health
- Plant Virus Research Studies
- Biochemical and Structural Characterization
- Adipose Tissue and Metabolism
- Sesquiterpenes and Asteraceae Studies
Trakia University
2001-2023
Science is still searching for readily available, cost-effective biomarkers to assess metabolic disorders occurring before the onset and during development of type-2 diabetes (T2DM). The aim present study was induce T2DM in rats through a high-fat diet, followed by single administration low dose streptozotocin (STZ), make an assessment disease. were divided into two groups—experimental control—and monitored period 10 days. Changes anthropometric parameters, glucose, insulin, lipids, uric...
The influence of stress upon the endocrine system and its relationship to immune have been studied. simulation chronic cold in rats caused an increase ACTH, corticosterone, T3 T4 levels. different hormonal background stressed animals affected characteristics intensity response, which was traced dynamics through action 10(9) ovine erythrocytes. A strong suppression B-lymphocytes PFC count observed. Increased Fc gamma-RFC-suppressing activity also determined. changed simultaneously with rate...
The optimisation of strategies for control Pseudomonas aeruginosa skin infections in dogs includes minimization induced hyper-inflammation.We aimed at monitoring changes serum nuclear factor kappa B (NF-кB) and nitric oxide (NO) concentrations, blood neutrophil/ lymphocyte ratio (N/L ratio), to evaluate their potential as inflammatory markers throughout the course therapy canine infection experimentally by P. aeruginosa.A complementary including antibiotic against pathogen NF-кB targeted...
Acute-phase response is most critical for the attenuation of strong inflammatory induced by bacterial opportunist Pseudomonas aeruginosa.The aim present study was to evaluate acute-phase in experimental aeruginosa skin infection, measuring changes fibrinogen concentration (a positive protein, APP) and activity arylesterase (AREa negative APP).We also aimed effect therapy with phytopreparation Feverfew, containing active component parthenolide, which has anti-inflammatory properties.Fifteen...
The aim of the experiment was to study effect exhaustive exercise on some cytokines and iron status parameters. We used 12 male, mongrel dogs divided into two groups – animals from experimental group were submitted at moderate intensity with exhaustion as end-point; control did no exercise. Serum levels tumour necrosis factor-α (TNF-α), interleukin-6 (IL-6), hepcidin prohormone, serum (SI), total binding capacity (TIBC) transferrin saturation (TS) measured before (BE), right after (0 hour)...
The aim of our study was to evaluate nonspecific defense mechanisms (phagocytosis and acute phase response) in dogs during an experimental infection caused by subcutaneous application Staphylococcus aureus (1x108 CFU/mL). neutrophils phagocytosis (evaluated fluorescein isothiocyanate labeled aureus) is activated at 48 h the phagocytic number remained high 72-nd infection. During early stage process (between 2-nd 24-th h) absolute segmented neutrophil count, band band-neutrophyl ratio, tend...
The aim of the present study was to investigate influence exhaustive exercise on some innate immunity parameters and cortisol levels. Twelve male, mongrel dogs were divided into an experimental group, submitted prolonged, strenuous with exhaustion as end-point, a control group without any exposure exercise. Serum levels measured before (BE), right after (0 h) 2nd hour 4th neutrophil function (phagocytosis, phagocytic index, hydrogen peroxide production-H2O2) classical pathway complement...
The еffect of Tanacetum parthenium (feverfew) on serum amyloid A (SAA) and free sialic acid (SA) were investigated in dogs.The animals divided into three groups: healthy dogs (Group I; n=5), infected subcutaneously with 1×10 8 CFU/mL field P. aeruginosa culture II; n=5) treated feverfew (90 mg standardised extract, 0.7% parthenolide) III; n=5).Oral phytopreparation (2 capsules daily) intake began from post infection hour 4 lasted 6 days.SAA concentrations increased insignificantly (16 mg/L)...