- Advanced Glycation End Products research
- Cancer Research and Treatments
- S100 Proteins and Annexins
- Neuroinflammation and Neurodegeneration Mechanisms
- MRI in cancer diagnosis
- Geomagnetism and Paleomagnetism Studies
- Cardiac Arrest and Resuscitation
- Acute Ischemic Stroke Management
- Radiation Therapy and Dosimetry
- Ultrasound and Hyperthermia Applications
- Spaceflight effects on biology
- Traumatic Brain Injury and Neurovascular Disturbances
Alpha MOS (France)
2025
Laboratoire de Physique des 2 Infinis Irène Joliot-Curie
2025
Université Paris Cité
2025
Université Paris-Saclay
2025
Centre National de la Recherche Scientifique
2025
Inserm
2018-2023
Institut Mondor de Recherche Biomédicale
2020-2023
Université Paris-Est Créteil
2023
École Nationale Vétérinaire d'Alfort
2023
Université Paris-Sud
2020
Abstract Iron oxide nanoparticles have been proposed for magnetic hyperthermia treatment of tumors. However, efficacy depends on the injection large amounts such and equipment is costly. Here, a new thermal cancer described, in which tumor containing low concentration nonpyrogenic pure iron nanominerals coated with carboxy‐methyl‐dextran (M‐CMD), corresponding to modified magnetosomes, are exposed ultrasound. Heating PC3 prostate carcinoma cells between 43 46°C using ultrasound presence...
Background High-mobility group box 1 (HMGB1) is a major promotor of ischemic injuries and aseptic inflammatory responses. We tested its inhibition on neurological outcome systemic immune response after cardiac arrest (CA) in rabbits. Methods Results After 10 minutes ventricular fibrillation, rabbits were resuscitated received saline (control) or the HMGB1 inhibitor glycyrrhizin. A sham underwent similar procedure without CA. resuscitation, glycyrrhizin blunted successive rises HMGB1,...
Introduction: After cardiac arrest, a sepsis-like syndrome is observed and contributes to poor prognosis. Hypothesis: This could be provoked by the massive release of Damage Associated Molecular Patterns (DAMP). Our aim was investigate role High mobility group box 1 (HMGB1), well-characterized nuclear DAMP, in an experimental model arrest. Methods: Rabbits were anesthetized submitted 10 min ventricular fibrillation. resuscitation, they either received administration inhibitor HMGB1...
Introduction: Profound immune disorders are triggered by cell death and subsequent release of danger signals after cardiac arrest (CA). Hypothesis: High mobility group box-1 (HMGB1) is one the main endogenous mediators released ischemic death. Our goal was to determine whether its inhibition could provide neuroprotection improve outcome experimental CA. Methods: After 10 min ventricular fibrillation resuscitation, rabbits either received an administration saline (CT group, n=10) or...
You have accessJournal of UrologyProstate Cancer: Basic Research & Pathophysiology I (MP33)1 Sep 2021MP33-19 TREATMENT OF PROSTATE CANCER USING LASER-IRRADIATED MAGNETOSOMES: A PRE-CLINICAL STUDY Cynthia El Hedjaj, Eric Barret, Imene Chebbi, and Edouard Alphandery HedjajCynthia Hedjaj More articles by this author , BarretEric Barret ChebbiImene Chebbi AlphanderyEdouard View All Author Informationhttps://doi.org/10.1097/JU.0000000000002042.19AboutPDF ToolsAdd to favoritesDownload...
You have accessJournal of UrologyProstate Cancer: Basic Research & Pathophysiology I (MP33)1 Sep 2021MP33-14 EFFICACY OF LOW INTENSITY ULTRASOUND-EXPOSED MAGNETOSOMES IN THE TREATMENT PROSTATE CANCER A XENOGRAFT MURINE MODEL Cynthia El Hedjaj, Eric Barret, Imene Chebbi, and Edouard Alphandery HedjajCynthia Hedjaj More articles by this author , BarretEric Barret ChebbiImene Chebbi AlphanderyEdouard View All Author Informationhttps://doi.org/10.1097/JU.0000000000002042.14AboutPDF ToolsAdd to...