- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Sex work and related issues
- Reproductive tract infections research
- Adolescent Sexual and Reproductive Health
- Syphilis Diagnosis and Treatment
- HIV Research and Treatment
- Blood groups and transfusion
- Cervical Cancer and HPV Research
- HIV/AIDS Impact and Responses
- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- HIV/AIDS oral health manifestations
- COVID-19 epidemiological studies
- Immune Cell Function and Interaction
- HIV/AIDS drug development and treatment
- Reproductive System and Pregnancy
- SARS-CoV-2 and COVID-19 Research
- T-cell and B-cell Immunology
- Pneumocystis jirovecii pneumonia detection and treatment
- COVID-19 Clinical Research Studies
- Bacillus and Francisella bacterial research
- Health Policy Implementation Science
- HIV-related health complications and treatments
- Infection Control and Ventilation
Instituut voor Tropische Geneeskunde
2015-2024
Fundação Oswaldo Cruz
2024
Research Institute for Tropical Medicine
2022-2023
Public Health Institute
2012-2023
University of Antwerp
2022
Sexual Health Clinic
1996-2021
Centers for Disease Control and Prevention
2015
Santé Espoir Vie Côte d'Ivoire
2003-2011
Family Health International 360
2010
Jet Company (Czechia)
2002-2004
The magnitude of the 2022 multi-country monkeypox virus (MPXV) outbreak has surpassed any preceding outbreak. It is unclear whether asymptomatic or otherwise undiagnosed infections are fuelling this epidemic. In study, we aimed to assess occurred among men attending a Belgian sexual health clinic in May 2022. We retrospectively screened 224 samples collected for gonorrhea and chlamydia testing using an MPXV PCR assay identified MPXV-DNA-positive from four men. At time sampling, one man had...
The COVID-19 pandemic most likely had a negative impact on mental health. Sexual minorities are at higher risk for adverse outcomes such as depression, anxiety and suicidal ideation. Such health disparities may have exacerbated during the pandemic, due to restricted real-life social contact. study aim was examine changes in ideation among Belgian sexual minority adults between periods before first lockdown. We conducted an online survey, which disseminated by community organizations...
Abstract NK cells are regulated in part by killer Ig-like receptors (KIR) that interact with HLA molecules on potential target cells. KIR and loci highly polymorphic certain KIR/HLA combinations were found to protect against HIV disease progression. We show this study interactions also influence resistance transmission. HIV-exposed but seronegative female sex workers Abidjan, Côte d’Ivoire, frequently possessed inhibitory genes the absence of their cognate genes: KIR2DL2/KIR2DL3...
Pre-Exposure Prophylaxis (PrEP) is highly effective in reducing the risk for HIV infection among men who have sex with (MSM) and may an important impact slowing down epidemic. Concerns remain however about low adherence, increased behaviour reduced condom use when using PrEP. The aim of this study was to assess these factors prospectively MSM daily event-driven PrEP Belgium.An open-label prospective cohort conducted from October 2017 May 2018 at Institute Tropical Medicine, Antwerp, Belgium....
To examine changes in the occurrence of physical sex with non-steady partners among men who have (MSM) Belgium during first weeks COVID-19 lockdown and associations sociodemographic factors, sexual practices, drug, alcohol pre-exposure prophylaxis (PrEP) use. A secondary objective was to explore PrEP use need for follow-up.
Little is known about the duration and protective capacity of humoral immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In studies from Iceland1Gudbjartsson DF Norddahl GL Melsted P et al.Humoral SARS-CoV-2 in Iceland.N Engl J Med. 2020; 383: 1724-1734Crossref PubMed Scopus (714) Google Scholar USA,2Wajnberg A Amanat F Firpo al.Robust neutralizing antibodies infection persist for months.Science. (published online Oct...
Objectives: To reduce the prevalence of curable sexually transmitted diseases (STDs) in a South African mining community through provision STD treatment services, including periodic presumptive and prevention education to core group high-risk women living areas around mines. Methods: Women at high risk for STDs attended mobile clinic monthly examination counseling, were treated presumptively bacterial with directly observed 1-g dose azithromycin. Gonococcal chlamydial infection rates...
A substantial proportion of women with gonococcal and/or chlamydial infection are asymptomatic. Thus active case detection is problematical, particularly in developing countries, where facilities and materials for laboratory testing limited. We assessed the diagnostic validity hierarchical clinical algorithms recommended by World Health Organization as well that a nonhierarchical scoring system, using data 1,160 pregnant (a low-prevalence group) 1,222 prostitutes high-prevalence Kinshasa,...
Objectives To assess condom use and prevalence of sexually transmitted infections (STI) HIV among male sex workers (MSW) in Abidjan, Côte d'Ivoire. Methods A cross-sectional survey was conducted between October 2007 January 2008 MSW attending a worker clinic Abidjan. short questionnaire administered face-to-face interview, the participants were asked to provide urine sample for STI testing self-collect transudate gingival mucosa anonymous testing, using rapid test. rectal swab taken by...
Daily pre-exposure prophylaxis and event-driven (PrEP) are efficacious in reducing HIV transmission among men who have sex with (MSM). We analyzed baseline data from a PrEP demonstration project "Be-PrEP-ared" Antwerp, Belgium, to understand preferences for daily or MSM at high risk of factors influencing their initial choice.Cross-sectional an open-label prospective cohort study, using mixed methods. Participants preregistered online were screened eligibility tested sexually transmitted...
Men who have sex with men (MSM) are at high risk of HIV. Few data available on MSM and HIV-related behaviors in West Africa. We aimed to describe vulnerability among Abidjan, Cote d'Ivoire. conducted a cross-sectional respondent-driven sampling survey 601 2011-2012. Sociodemographic behavioural as well related emotional state stigma were collected. Population estimates 95% confidence intervals produced. Survey weighted logistic regression was used assess factors associated inconsistent...
Mpox (formerly monkeypox) is a viral disease caused by the mpox virus (MPXV), endemic in Central and West Africa currently causing global outbreak of international concern. Much remains unknown about sample types most suited for laboratory diagnosis. While it established that high loads can be found active skin lesions (currently recommended confirmation specimen type), WHO testing guidelines encourage use oropharyngeal swabs as an additional type diagnosis suggest investigating value other...
Oral pre-exposure prophylaxis (PrEP) with emtricitabine/tenofovir disoproxil fumarate (F/TDF) has high efficacy against HIV-1 acquisition. Seventy-two prospective studies of daily oral F/TDF PrEP were conducted to evaluate incidence, drug resistance, adherence, and bone renal safety in diverse settings. incidence was calculated from incident diagnoses after initiation within 60 days discontinuation. Tenofovir concentrations dried blood spots (DBS), bone/renal indicators evaluated a subset...
Abstract Background Data on human immunodeficiency virus (HIV) seroconversion among men who have sex with (MSM) using pre-exposure prophylaxis (PrEP) in West Africa are needed. This study aimed to document HIV and associated determinants, PrEP adherence, plasma drug concentrations, resistance MSM event-driven or daily Burkina Faso, Côte d’Ivoire, Mali, Togo. Methods A prospective cohort was conducted 2017–2021 HIV-seronegative aged 18 over were at high risk of infection. Participants could...
Objective To assess condom use and prevalence of STIs HIV among female sex workers (FSWs), as part a comprehensive monitoring evaluation plan nationwide worker prevention project in Côte d'Ivoire. Design Methods Cross sectional surveys were conducted FSWs attending five clinics Abidjan San Pedro (2007), Yamoussoukro Gagnoa (2009). A standardized questionnaire was administered face-to-face interview, which included questions on socio-demographic characteristics, sexual behaviour use. After...
To determine HIV prevalence and associated risk factors among men who have sex with (MSM) in Abidjan, Côte d'Ivoire. We conducted a cross-sectional RDS survey of MSM Abidjan from October 2011 to February 2012. Eligibility criteria included age ≥ 18 years having had oral or anal another man the last 12 months. Weighted data analysis was RDSAT SAS. enrolled 603 participants, whom 601 (99.7%) completed questionnaire 581 (96.7%) consented testing. population estimated as 18.0% (95% CI:...