A5075397682- Spinal Dysraphism and Malformations
- Assisted Reproductive Technology and Twin Pregnancy
- Congenital Anomalies and Fetal Surgery
- Congenital Diaphragmatic Hernia Studies
- Fetal and Pediatric Neurological Disorders
- Cerebrospinal fluid and hydrocephalus
- Prenatal Screening and Diagnostics
- Neonatal Respiratory Health Research
- Pregnancy and preeclampsia studies
- Tracheal and airway disorders
- Grief, Bereavement, and Mental Health
- Teratomas and Epidermoid Cysts
- Congenital gastrointestinal and neural anomalies
- Cardiovascular Disease and Adiposity
- Sepsis Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Intestinal Malrotation and Obstruction Disorders
- Diabetes Management and Research
- Diabetes Treatment and Management
- Adipose Tissue and Metabolism
- COVID-19 Clinical Research Studies
- Preterm Birth and Chorioamnionitis
- Diabetes Management and Education
- Esophageal and GI Pathology
- Hernia repair and management
Texas Children's Hospital
2019-2025
Baylor College of Medicine
2019-2025
The University of Texas at Dallas
2023
Royal Berkshire NHS Foundation Trust
2023
University of Auckland
2022
The Kids Research Institute Australia
2019
University of Minnesota
2019
University of Toronto
2019
Rochester Institute of Technology
2015
Tulane Medical Center
2014
ABSTRACT Objectives To compare the ambulatory status of a cohort children who had undergone prenatal repair an open neural tube defect (ONTD) using one two different methods (fetoscopic or hysterotomy) with that postnatal repair, and to identify best predictors ambulation at 30 months age. Methods This was retrospective review underwent ONTD either prenatally ( n = 110), by fetoscopic surgery 73) hysterotomy 37), postnatally 51), in single tertiary hospital between November 2011 May 2023....
In Brief OBJECTIVE: To evaluate the screening performance characteristics of existing tools for diagnosis sepsis during delivery admissions. METHODS: This was a case–control study using electronic health record data, including vital signs and laboratory results, all admissions patients with from 59 nationally distributed hospitals. Patients were matched by gestational age at in 1:4 ratio without to create comparison group. chorioamnionitis compared complete cohort sepsis. Multiple criteria...
OBJECTIVE: To evaluate the performance characteristics of existing screening tools for prediction sepsis during antepartum and postpartum readmissions. METHODS: This was a case–control study using electronic health record data obtained between 2016 2021 from 67 hospitals admissions 71 readmissions up to 42 days. Patients in case group were matched 1:4 ratio comparison cohort patients without admitted or postpartum. The following criteria evaluated: CMQCC (California Maternal Quality Care...
Assessment of inpatient mortality risk in COVID-19 patients is important for guiding clinical decision-making. High sensitivity cardiac troponin T (hs-cTnT) a biomarker injury associated with worse prognosis COVID-19. We explored how hs-cTnT could potentially be used practice ruling and out COVID-19.We tested the diagnostic value laboratory-confirmed (≥18 years old) admitted to Royal Berkshire Hospital (UK) between 1st March 10th May 2020. A normal was defined as within 99th percentile...
3D printing technologies can address many sustainability aspects of creating new materials, such as reduced waste and on demand production, which reduces the carbon footprint transport storage.
To identify predictors for intact motor function (MF) at birth and 12 months of life in babies with prenatally versus postnatally repaired open spina bifida (OSB).Retrospective cohort study.Texas Children's Hospital, 2011-2018.Patients who underwent either prenatal or postnatal OSB repair.Prenatal MF the lower extremities was evaluated by ultrasound following a metameric distribution time diagnosis (US1), 6 weeks postoperatively (or after initial evaluation cases) (US2) last before delivery...
Prenatal open neural tube defect (ONTD) repair is performed to decrease the risk of needing treatment for hydrocephalus after birth and preserve motor function. Some centers may not consider patients be candidates surgery if severe ventriculomegaly present there no expected benefit in treatment. This study sought compare postnatal outcome fetuses with ONTD (ventricular width ≥ 15 mm) that underwent prenatal without (< repair.
This study reports the infant to preschool outcomes of a laparotomy-assisted, two-port fetoscopic myelomeningocele (MMC) repair and compares results with those contemporary, same-center cohort that underwent either fetal MMC surgery via hysterotomy or postnatal repair.
(1) To compare brain findings between large and non-large neural tube defect (NTD); (2) to evaluate the impact of lesion on surgical parameters; (3) study any associations size lesions 6 weeks postoperatively neurological short-term outcomes.Retrospective cohort study.Texas Children's Hospital, 2011 2018.Patients who underwent prenatal NTD repair.Large was defined when lesion's surface >75th centile our cohorts' lesions.Time referral: ventriculomegaly anatomical level lesion; surgery:...
Introduction: The ferritin–lymphocyte ratio (FLR) is a novel inflammatory biomarker for the assessment of acute COVID-19 patients. However, prognostic value FLR predicting adverse clinical outcomes in remains unclear, which hinders its translation. Methods: We characterised patients, as compared to established markers. Results: In 217 study patients (69 years [IQR: 55–82]; 60% males), was weakly correlated with CRP (R = 0.108, p 0.115) and white cell count −0.144; 0.034). On ROC analysis, an...
To evaluate the association of laser photocoagulation placental anastomoses (LPA) prior to 18 weeks' gestation (early LPA) with very preterm delivery and neonatal survival in pregnancies twin-twin transfusion syndrome (TTTS).This was a retrospective cohort study monochorionic diamniotic twin TTTS undergoing LPA between 2002 2018 at two institutions. The rates < 28, 30 32 gestation, prelabor rupture membranes (PPROM) 30-day one or both infants were compared early those ≥ gestation. Regression...
To determine the impact of lesion type (cystic [myelomeningocele] or flat [myeloschisis]) on fetal motor function (MF) in cases candidates for prenatal open neural tube defect (ONTD) repair.Retrospective cohort study patients with ONTD who underwent repair at a single institution between 2011 and 2019. The measurements length width lesions to calculate surface ellipsoid were performed using MR scans. Prenatal MF lower extremities was evaluated by ultrasound following metameric distribution...
Introduction: The aim of the study was to characterize changes in fetal lung volume following fetoscopic endoluminal tracheal occlusion (FETO) that are associated with infant survival and need for extracorporeal membrane oxygenation (ECMO) congenital diaphragmatic hernia (CDH). Methods: Fetuses CDH who underwent FETO at a single institution were included. cases reclassified by MRI metrics [observed-to-expected total (O/E TLV) percent liver herniation]. after calculated. ROC-derived cutoffs...
The purpose of the research was to explore challenges, frustrations and experiences faced by young Australian adults with type 1 diabetes. We focused on navigation health behaviours (e.g. eating out, consuming alcohol, physical activity), which impact blood glucose levels, posing particular challenges for people Semi-structured interviews were conducted 25 diabetes, between May August 2016. Interviews transcribed verbatim, coded using thematic analysis. Participants reported that experience...
Abstract To investigate the association of myelomeningocele (MMC) volume with prenatal and postnatal motor function (MF) in cases who underwent a repair. Retrospective cohort study (11/2011 to 03/2019) 63 patients MMC repair (37 fetoscopic, 26 open-hysterotomy). At referral, measurements was performed based on ultrasound scans. A large defined as greater than optimal threshold (ROC analysis) for prediction intact MF at referral (2.7 cc). Prenatal or (S1) observation plantar flexion ankle...