Huizhen Zhang

ORCID: 0000-0003-0520-1955
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About
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Research Areas
  • Antioxidant Activity and Oxidative Stress
  • Bacteriophages and microbial interactions
  • Topological Materials and Phenomena
  • Photonic and Optical Devices
  • Metamaterials and Metasurfaces Applications
  • Plasmonic and Surface Plasmon Research
  • Photonic Crystals and Applications
  • Pneumonia and Respiratory Infections
  • Aquaculture disease management and microbiota
  • CAR-T cell therapy research
  • Bone Tumor Diagnosis and Treatments
  • Iron Metabolism and Disorders
  • Water Quality Monitoring and Analysis
  • Dermatologic Treatments and Research
  • Urological Disorders and Treatments
  • Machine Learning in Bioinformatics
  • Quantum Mechanics and Non-Hermitian Physics
  • Immunotherapy and Immune Responses
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Pleural and Pulmonary Diseases
  • Wound Healing and Treatments
  • Cancer Diagnosis and Treatment
  • Hemoglobinopathies and Related Disorders
  • Environmental Quality and Pollution
  • Traditional Chinese Medicine Studies

Beijing Institute of Technology
2020-2025

Shanghai Sixth People's Hospital
2019-2023

Shanghai Jiao Tong University
2023

Anhui Medical University
2022-2023

Sichuan University
2023

China Agricultural University
2022

Jiangxi Agricultural University
2022

Children's National
2017-2021

Zhengzhou University
2009-2021

Shandong Institute of Food and Drug Inspection
2019

Abstract Topological photonics provides a new degree of freedom to robustly control electromagnetic fields. To date, most established topological states in have been employed Euclidean space. Motivated by unique properties hyperbolic lattices, which are regular tessellations non-Euclidean space with constant negative curvature, the boundary-dominated proposed. However, limited highly crowded boundary resonators and complicated site couplings, insulator has only experimentally constructed...

10.1038/s41467-024-46035-y article EN cc-by Nature Communications 2024-02-22

Allium mongolicum Regel (AM), widely distributed in western China, is a traditional Mongolian medicine herb. Two different solvents as water and methanol were used to extract AM, their antioxidant capacity inhibitory effects against key enzymes related metabolic syndrome assessed. The was evaluated through the assay of radical scavenging ability on DPPH ABTS reducing power assays. In addition, total phenolic content flavonoids quantificated analyzed. Aqueous extract, having higher (10.20 mg...

10.1002/fsn3.926 article EN cc-by Food Science & Nutrition 2019-01-28

Exceptional points (EPs), branch of complex energy surfaces at which eigenvalues and eigenvectors coalesce, are ubiquitous in non-Hermitian systems. Many novel properties applications have been proposed around the EPs. One important is to enhance detection sensitivity. However, due lack single-handed superchiral fields, all EP-based sensing mechanisms only useful for nonchiral discrimination. Here, we propose theoretically demonstrate experimentally a new type EP, called radiation vector...

10.1103/physrevlett.124.083901 article EN Physical Review Letters 2020-02-26

Abstract Bound states in the continuum (BICs) provide an important way for creating photonic devices reliant upon optical modes with high Q‐factors. However, current experimental implementations of BICs crystal (PhC) slabs only possess a certain polarization, which fundamentally restricts their use to surface‐enhanced applications assisted by scalar‐polarized near fields. In this work, vector PhC are theoretically designed and experimentally realized. theory, symmetry‐protected can be...

10.1002/adom.202203118 article EN Advanced Optical Materials 2023-03-24

Trapping electromagnetic waves within the radiation continuum holds significant implications in field of optical science and technology. Photonic bound states (BICs) present a distinctive approach for achieving this functionality, offering potential applications laser systems, sensing technologies, other domains. However, simultaneous achievement high Q-factors, flat-band dispersions, wide-angle responses photonic BICs has not yet been reported, thereby impeding their practical performance...

10.1038/s41467-024-53433-9 article EN cc-by-nc-nd Nature Communications 2024-10-21

Abstract Neoantigen discovery in pediatric brain tumors is hampered by their low mutational burden and scant tissue availability. Here we develop a proteogenomic approach combining tumor DNA/RNA sequencing mass spectrometry proteomics to identify tumor-restricted (neoantigen) peptides arising from multiple genomic aberrations generate highly target-specific, autologous, personalized T cell immunotherapy. Our data indicate that aberrant splice junctions are the primary source of neoantigens...

10.1038/s41467-021-26936-y article EN cc-by Nature Communications 2021-11-18

The hybrid of silicon and erbium-doped crystals provides a promising photonic platform for the advancement quantum technologies, combining scalability, telecom compatibility, complex functionalities. However, inherent high refractive index leads to optical field confinement within silicon, limiting number optically active erbium ions achievable light absorption, which are essential various applications. To fully utilize potential crystals, we implemented bound states in continuum structures,...

10.1364/oe.555348 article EN cc-by Optics Express 2025-02-20

Abstract Robust Integrable Quantum Optical Sources, Constructed by Topological Boundary States, Are Crucial for the on‐chip Information Processing. However, Limited Bulk‐edge Correspondence, Implementation of Channels Necessitates a Substantial Number Bulk Sites, Which Notably Diminishes Ratio Ring Resonators to Generate Sources. How Achieve Topologically‐protected Sources With Extremely Enhanced Utilization Efficiency Remains Challenge. Here, First Realization Hyperbolic is reported,...

10.1002/advs.202417708 article EN cc-by Advanced Science 2025-03-17

Antarctic krill (Euphausia superba) is one of the important bioresources in waters, containing many bioactives (e.g., astaxanthin), which have a highly potential value for commercial exploitation. In this study, effects processing methods on content, structural isomers, and composition astaxanthins (free astaxanthin esters) were studied. Three drying methods, comprising freeze-drying, microwave drying, hot-air used. Free (Ast), monoesters (AM), diesters (AD) boiled (control) dried extracted...

10.1021/acsomega.9b01294 article EN publisher-specific-oa ACS Omega 2019-10-25

Abstract The polarization beam splitter (PBS) is the essential optical component, which widely used in various instruments. Its robustness against perturbation very necessary to all-optical classical and quantum networks. Here, we report design of topologically protected vector edge states (dual-polarization with transverse electric magnetic modes) PBS based on all-dielectric topological valley photonic crystal slabs. have been realized for first time using germanium slab silica substrate....

10.1088/1367-2630/ac20eb article EN cc-by New Journal of Physics 2021-08-25

The topic of bacteriophage as an alternative to antibiotics control pathogenic bacteria has attracted attention. Here, a novel virulent Salmonella JNwz02 capable cross-infecting E. coli O157:H7 was isolated and characterized. complete genome composed 114390 bp double-stranded DNA molecules encoding 164 open reading frames (ORFs) with G + C content 40.22%. belongs the Siphoviridae family high homology T5-type phages. eclipse period latency infection were 10 min 10–15 min, respectively. burst...

10.1016/j.lwt.2022.114251 article EN cc-by-nc-nd LWT 2022-12-06

Resveratrol (Res) is known to have potent anti-inflammatory and antioxidant effects inhibit platelet aggregation the growth of a variety cancer cells. In this study, we investigated Res on expression vascular endothelial factor (VEGF) gene cell proliferation in human renal (786-0) The 786-0 cells were treated with various concentrations (0, 10, 20 40 µmol/l) for different time periods (24, 48 72 h). Cell was examined by MTT analysis VEGF analyzed RT-PCR Western blot analysis. inhibited gene,...

10.3892/mmr.2011.511 article EN Molecular Medicine Reports 2011-06-17

Iron-overload disorders are common and could lead to significant morbidity mortality worldwide. Due limited treatment options, there is a great need develop novel strategies remove the excess body iron. To discover potential epigenetic modulator in hepcidin upregulation subsequently decreasing iron burden, we performed an screen. The vivo effects of identified compounds were further tested iron-overload mouse models, including Hfe-/-, Hjv-/-, hepatocyte-specific Smad4 knockout...

10.1089/ars.2017.7161 article EN Antioxidants and Redox Signaling 2017-11-08

Summary A new gelatin‐protocatechuic acid (PCA) film with Escherichia coli O157:H7 phage JN01 was developed and characterised. After incorporated JN01, swelling value, water vapour permeability, solubility elongation at break of gelatin‐PCA were not significantly different. The addition increased b value transparency film, while it decreased L a tensile strength film. Moreover, the gelatin‐PCA‐JN01 presented antioxidant activity 60.07%. Furthermore, could be steadily released from...

10.1111/ijfs.15673 article EN International Journal of Food Science & Technology 2022-03-04

Community-acquired pneumonia (CAP) patients usually present with parapneumonic pleural effusion (PPE), which complicates the treatment of pneumonia. This study aims to investigate clinical characteristics and risk factors elderly CAP hospitalised PPE.The data 132 were retrospectively analysed. A total 54 PPE (PPE group) 78 without (NPPE included in this study. Clinical data, laboratory examinations, treatments other relevant indicators collected. Univariate analysis multivariate logistic...

10.1186/s12890-023-02649-4 article EN cc-by BMC Pulmonary Medicine 2023-09-20

Chirality is ubiquitous in natural world. Although with similar physical and chemical properties, chiral enantiomerscould play different roles biochemical processes. Discrimination of enantiomers extremely important biochemical, analytical chemistry, pharmaceutical industries. Conventional chiroptical spectroscopic methods are disadvantageous at a limited detection sensitivity because the weak signals molecules. Recently, superchiral fields were proposed to effectively enhance interaction...

10.1088/1674-1056/ac11df article EN Chinese Physics B 2021-07-07
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