A5067051052- Exercise and Physiological Responses
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Air Quality and Health Impacts
- Cardiovascular and exercise physiology
- Glioma Diagnosis and Treatment
- Healthcare Regulation
- Muscle metabolism and nutrition
- Pediatric health and respiratory diseases
- Nutrition and Health in Aging
- Bariatric Surgery and Outcomes
- High Altitude and Hypoxia
- Adipokines, Inflammation, and Metabolic Diseases
- Dermatological and COVID-19 studies
- Physical Education and Training Studies
- COVID-19 Clinical Research Studies
- Rabbits: Nutrition, Reproduction, Health
- Vitamin C and Antioxidants Research
- Salivary Gland Tumors Diagnosis and Treatment
- Helminth infection and control
- Indoor Air Quality and Microbial Exposure
- Cancer, Stress, Anesthesia, and Immune Response
- Photodynamic Therapy Research Studies
Universidade de São Paulo
2021-2025
Brazilian Agricultural Research Corporation
2025
Universidade Federal de São Paulo
2012-2024
University of California, Los Angeles
2024
Universidade Federal do Vale do São Francisco
2024
Union des Industries Ferroviaires Européennes
2012-2020
Instituto Português de Oncologia Francisco Gentil
2016-2018
San Antonio College
2018
University of Coimbra
2018
Universidade Federal Fluminense
2017-2018
Advanced head and neck squamous cell carcinoma, after locoregional treatment multiple lines of systemic therapies, represents a great challenge to overcome acquired resistance. The present clinical case illustrates successful option is the first describe use photodynamic therapy (PDT) with Redaporfin, followed by immune checkpoint inhibition an anti-PD1 antibody. This patient presented extensive tumor in mouth pavement progressing surgery, radiotherapy, treatment. PDT Redaporfin achieved...
It has been hypothesized that persistent ketotic hypoglycemia represents a potential therapeutic strategy against high‑grade gliomas. Perillyl alcohol (POH) is non‑toxic, naturally‑occurring, hydroxylated monoterpene exhibits cytotoxicity temozolomide‑resistant glioma cells, regardless of O6‑methylguanine‑methyltransferase promoter methylation status. The present study aimed to evaluate the toxicity and efficacy intranasal POH when administered in combination with ketogenic diet (KD) program...
Background. Although Lactobacillus casei Shirota (LcS) can benefit the immune status, effects of LcS in immune/inflammatory responses marathon runners has never been evaluated. Therefore, here we evaluated effect daily ingestion fermented milk containing or not systemic and upper airway before after a marathon. Methods. Forty-two male ingested 40 billion LcS/day (LcS group, n = 20) placebo (unfermented milk, 22) during 30 days pre-marathon. Immune/inflammatory parameters nasal mucosa serum,...
We investigated the effects of oral L-glutamine (Gln) supplementation, associated or not with physical exercises, in control glycemia, oxidative stress, and strength/power knee muscles elderly women. Physically active (n = 21) sedentary 23) women aged 60 to 80 years were enrolled study. Plasma levels D-fructosamine, insulin, reduced (GSH) oxidized (GSSG) glutathione, iron, uric acid, thiobarbituric acid-reactive substances (TBARs) (lipoperoxidation product), as well extensor/flexor muscle...
Likely as in other viral respiratory diseases, SARS-CoV-2 elicit a local immune response, which includes production and releasing of both cytokines secretory immunoglobulin (SIgA). Therefore, this study, we investigated the levels specific-SIgA for airways mucosa 37 patients who were suspected COVID-19. According to RT-PCR results, separated into three groups: negative COVID-19 viruses (NEGS, n = 5); but positive presence (OTHERS, (COVID-19, 27). Higher SARS-CoV-2, IFN-β, IFN-γ found group...
OBJETIVO: Identificar e relacionar a composição corporal, baseada na porcentagem de gordura corporal o índice massa corpórea (IMC), idade da menarca, com capacidade aeróbia, utilizando-se os valores VO2 máximo indireto, estudantes do segundo ciclo ensino fundamental. MÉTODOS: Foram avaliadas 197 meninas média 13,0±1,2 anos, duas escolas estaduais Atibaia-SP. Para estimar foi realizada uma avaliação dobras cutâneas protocolo Slaughter para adolescentes. Já medido em quilogramas por metro...
<b><i>Objective:</i></b> To evaluate the relationship between inflammatory profile and mood states in different phases of menstrual cycle soccer players with without premenstrual syndrome (PMS). <b><i>Methods:</i></b> Data on were collected using Daily Symptom Report Brunel Mood Scale. Cytokine stress hormone concentrations measured urine by flow cytometry before after a game luteal phase follicular one cycle....
Although regular combined aerobic-resistance exercises can ameliorate the inflammatory status and redox balance in elderly population, it is unclear whether protein or specific amino acid supplementation could improve such benefits. Therefore, we aimed to evaluate indexes through of saliva 34 subject nonpractitioners (NP group, 73.3 ± 6.6 years) 49 practitioners a combined-exercise training moderate intensity (CET 71.9 5.8 before (pre) after (post) 30 days with L-glutamine (Gln) placebo...
Background Previous studies have shown that increasing physical activity in daily life (PADL) improves asthma clinical control and quality of life. However, the minimal clinically important difference (MCID) to promote those improvements remains poorly known. The aim this study was estimate MCID for PADL people with moderate-to-severe asthma. Methods Data from consecutive who completed an eight-week (1x/week) face-to-face behavioural intervention increase were included compute MCID....
<sec> <title>BACKGROUND</title> (Actigraph) for seven days to assess daily life physical activity (DLPA). Then, the participants will be randomized into ET or sham groups, and both groups complete a PR program (2x/week 8 weeks). The group receive ET, whereas non-elastic tape. Data presented as means standard. Individuals with severe chronic obstructive pulmonary disease (COPD) may exhibit thoracoabdominal asynchrony (TAA), which reduces ventilatory efficiency. A novel intervention using...
The COVID-19 pandemic has altered food safety and hygiene behaviors. This study used a combined qualitative quantitative approach to investigate the adaptations of these practices in Brazil during after pandemic. Five distinct participant profiles were for focus groups: homemakers, undergraduate students from various fields, industry professionals (such as engineers, technologists, nutritionists), healthcare (nurses, doctors, technicians), vaccinated individuals. Focus groups with 41...
Objective: To explore the associations between preestablished daily step count cut-offs and health status, dyspnoea, psychosocial distress in individuals with COPD. Methods: A cross-sectional analysis was performed on 252 PADL objectively assessed using a triaxial accelerometer, participants were categorized as physically active or inactive according to three previously reported for COPD (4,300, 4,580, 5000 steps/day). Health status measured via Assessment Test (CAT) Clinical Questionnaire...
Several locoregional techniques have been described for the management of acute and chronic pain after breast surgery. The optimal technique should be easy to perform, reproducible, with little discomfort patient, complications, allowing good control a decreased incidence pain, namely intercostobrachial neuralgia being most frequent entity. aim this study was evaluate paravertebral block preoperative single needle prick major surgery assess initially postoperative nausea vomiting (PONV) in...
Age-related decreases in muscle function lead to disabilities and are associated with negative health outcomes older people. Although several physical tests can be used assess performance, strength, power, their interpretation hampered by the ceiling effect of some them. The aim this study was whether vertical jump safe terms integrity they useful assessing performance forty-one robust women. investigation entailed an assessment anthropometric characteristics, functioning (Short Physical...
Estão descritas várias técnicas locorregionais para a abordagem da dor aguda e crônica após cirurgia de mama. O ideal seria uma técnica fácil fazer, reprodutível, com pouco desconforto as doentes, poucas complicações que permitirá um bom controle diminuição incidência crônica, notadamente neuropática do intercostobraquial, por ser entidade mais frequente. Estudar aplicação bloqueio paravertebral picada única no pré‐operatório mamária grande porte. Avaliar numa primeira fase o náuseas‐vômitos...
Although regular exercise-training improves immune/inflammatory status, the influence of air pollutants exposure during outdoor endurance training compared to a sedentary lifestyle has not yet been clarified. This study aimed compare responses in airways street runners and people after acute chronic particulate matter (PM) exposure. Forty volunteers (street (RUN, n = 20); (SED, 20)) were evaluated 1 (acute) 10 (chronic) weeks PM Cytokines [interferon (IFN)-γ, tumor necrosis factor (TNF)-α,...
At present, it is unclear which exercise-induced factors, such as myokines, could diminish the negative impact of reduction in pulmonary function imposed by exercise question. In this study, we aim to evaluate prevalence bronchoconstriction (EIB) and also investigate effect myokines performance marathon runners presenting EIB or not. Thirty-eight male recreational (age 38.8 [33–44], height 175.7 [172.0–180.3]; weight 74.7 [69.3–81.6]) participated through spirometry tests, a 23.6% was found,...
Chronic cytomegalovirus (CMV) infection is a trigger factor for the development of immunosenescence and negatively impacts immune response to influenza virus vaccination (IVV) in older adults. However, role physical exercise training this context unknown. Thus, aim study was investigate whether regular practice combined can improve specific antibody IVV CMV-seropositive Eighty adults were distributed into two groups—non-practitioners (NP, n = 31, age 74.06 ± 6.4 years) practitioners (CET,...
Obesity is a troubling public health problem as it increases risks of sleep disorders, respiratory complications, systemic arterial hypertension, cardiovascular diseases, type 2 diabetes mellitus, and metabolic syndrome (MetS). As measure to counteract comorbidities associated with severe obesity, bariatric surgery stands out. This study aimed investigate the adiponectin/leptin ratio in women obesity without MetS who had undergone Roux-en-Y gastric bypass (RYGB) characterize biochemical,...
Background: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the overproduction of white blood cells, leading to symptoms such as fatigue, infections, and other complications. CML patients must take measures prevent infections mitigate exacerbation cancer cell proliferation comorbidities. Methods: This study investigated whether vitamin C can suppress hyperinflammatory activation K-562 cells induced lipopolysaccharide (LPS) purinergic signaling (ATP P2X7...